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Last Update 12/11/2009
Original Papers

Total synthesis and biological evaluation of (+)-neopeltolide and its analogues
H. Fuwa, A. Saito, S. Naito, K. Konoki, M. Yotsu-Yamashita, and M. Sasaki.
Chem. Eur. J., 15, 12807-12818 (2009).

Toward the total synthesis of goniodomin A, an actin-targeting marine polyether macrolide: Convergent synthesis of the C15-C36 segment.
T. Saito, H. Fuwa, and M. Sasaki.
Org. Lett., 11, 5274-5277 (2009).

Regioselective domino metathesis of unsymmetrical 7-oxanorbornenes with electron-rich vinyl acetate toward biologically active glutamate analogues
M. Oikawa, M. Ikoma, M. Sasaki, M. B. Gill, G. T. Swanson, K. Shimamoto, and R. Sakai.
Eur. J. Org. Chem., 5531-5548 (2009).

Stereocontrolled synthesis of the DEFG-ring skeleton of gambieric acids
H. Fuwa, S. Noji, and M. Sasaki.
Chem. Lett., 38, 866-867 (2009).

Full domain closure of the ligand-binding core of the ionotropic glutamate receptor iGluR5 induced by the high affinity agonist dysiherbaine and the functional antagonist 8,9-dideoxyneodysiherbaine
K. Frydenvang, L. L. Lash, P. Naur, P. A. Postila, D. S. Pickering, C. M. Smith, M. Gajhede, M. Sasaki, R. Sakai, O. T. Pentikainen, G. T. Swanson, and J. S. Kastrup.
J. Biol. Chem., 284, 14219-14229 (2009).

Synthetic studies on gambieric acids, potent antifungal polycyclic ether natural products: Reassignment of the absolute configuration of the nonacyclic polyether core by NMR analysis of model compounds
H. Fuwa, K. Ishigai, T. Goto, A. Suzuki, and M. Sasaki.
J. Org. Chem., 74, 4024-4040 (2009).

This paper was selected as a Featured Article of The Journal of Organic Chemistry.

Proteomic analysis reveals multiple patterns of response in cells exposed to a toxin mixture
G. L. Sala, G. Ronzitti, M. Sasaki, H. Fuwa, T. Yasumoto, A. Bigiani, and G. P. Rossini.
Chem. Res. Toxicol., 22, 1077-1085 (2009).

This paper was highlighted in In this issue of Chemical Research in Toxicology.

Synthesis of open-chain C21-C40 fragment of azaspiracid-1
M. Oikawa, T. Iwayama, and M. Sasaki.
Heterocycles, 78, 609-615 (2009).

Chemospecific allylation and domino metathesis of 7-oxanorbornenes for skeletal and appendage diversity
M. Ikoma, M. Oikawa and M. Sasaki.
Eur. J. Org. Chem., 72-84 (2009).

Synthesis of 2-substituted indoles and indolines via Suzuki-Miyaura coupling/5-endo-trig cyclization strategies.
H. Fuwa and M. Sasaki.
J. Org. Chem., 74, 212-221 (2009).

Reviews and Accounts

抗腫瘍性海産マクロリド (+)-ネオペルトリドの全合成
佐々木 誠、不破春彦
, 45, 439-444 (2009).


T. N. Sorrell著/村田道雄 ・石橋正己・木越英夫・佐々木誠 監訳

佐々木 誠、塚野千尋
天然物全合成の最新動向(北泰行監修、シーエムシー出版)、pp 228-243 (2009).

天然物の全合成 2000〜2008(日本)(有機合成化学協会編)
佐々木 誠

佐々木 誠 編集
平成21年度 生体物質 物182−物193、生理活性物質195−199.

Copyright(C) Sasaki Group 2009