業績集 Works of Our Lab.



著書  Books (in Japanese)


  1. 獣医組織学 第4版 (編集:日本獣医解剖学会,学窓社,2008) 分担執筆:渡邊康一・山口高弘,「第6章 筋組織」,p.69-79.
     
  2. カラーアトラス獣医解剖学(上・下巻) (著:H.E. Konig & H.-G. Liebich,監訳:カラーアトラス獣医解剖学編集委員会,チクサン出版,2008,分担訳:山口高弘・渡邊康一,第2章 p.151-160.
     
  3. "ファイバー" スーパーバイオミメティックス 近未来の新技術創成 (監:本宮達也,編:赤池敏宏ほか,エヌ・ティー・エス,2006,分担執筆:山口高弘・渡邊康一,「生体における運動例:動物の動き概論」p.84-90.
     
  4. まなびの杜 東北大学 知的探検のススメ Vol. II (編:東北大学「まなびの杜」編集委員会,共著:渡邊康一,山口高弘,東北大学,2006

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  6. 図説 動物形態学 (編著:福田勝洋,共著:山口高弘ほか,朝倉書店,2006

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  8. 牛の解剖アトラス (監訳:日本獣医解剖学会,チクサン出版社,2005) 分担訳:山口高弘(第3章 頭,p.30-31)

  9.  
  10. 獣医組織学 第3版 (編集:日本獣医解剖学会,学窓社,2005) 分担執筆:山口高弘・渡邊康一(第6章 筋組織,p.65-75)

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  12. サイエンスビュー生物総合資料(生物I・II/理科総合B対応) (監修:長野 敬,牛木辰男,実教出版,2004) 写真提供:山口高弘(下垂体,膵臓)
     
  13. 応用生命科学のための生物学入門 改訂版 (監修:羽柴輝良,山口高弘,培風館,2003) 分担執筆:山口高弘(p.1-10, 13-15)

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  15. 牛の脳アトラス Brain Atlas of Cattle (編集:岡村裕昭,著者:市丸 徹,大蔵 聡,岡村裕昭,小堤恭平,斎藤敏之,根本 鉄,山岸規昭,山口高弘,農林水産省畜産試験場,2001) 「家畜の脳・神経機能の解明と評価に関する基礎的研究」

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  17. 食肉科学の道 ―その過去から未来へ  (編集:伊藤肇躬・鈴木敦士,ミドリ印刷,2000) 分担執筆:山口高弘,今中崇博,奈良英利(ウシ骨格筋形成におけるサイトカインの役割, p.69-78)

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  19. 食と生体防御 BioDefenceシリーズ4 (編集:日本生体防御学会,森 勝義  菜根出版,紀伊國屋書店,1999)  分担執筆:山口高弘,小峯健一,浅井健一,貝 健三,森 優美子,黒石智成,熊谷勝男(第1章−5.乳牛乳腺の泌乳サイクルと免疫応答 p.111-139)

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  21. 反芻動物の栄養生理学 (監修:佐々木康之,編集:小原嘉昭,農山漁村文化協会,1998) 分担執筆:山口高弘(第8章 筋芽細胞からの情報 p.430-443)

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  23. 応用生命科学のための生物学入門 (監修:谷口 旭,羽柴輝良 編集:遠藤宜成,駒井三千夫,鳥山欽哉,中井 裕,牧野 周,松谷武成,山口高弘,培風館,1998) 分担執筆:山口高弘(第2章 細胞の機能 p.49-92,第5章−2 動物の生理 p.201-211)

  24.  

著書(英文)  Books (in English)


  1. Reproductive Biology Update (Eds.: Miyamoto H. and Manabe N., Shokadoh Booksellers Company, Kyoto, 1998) Section 4. Neuronal and hormonal regulation mechanisms in reproductive systems:  Heterogeneity and development of Somatotrophs and mammotrophs in domestic animals.  Yamaguchi T., Ide Y., Sato T., Nara H., Matsuzaki M.  p.305-313.

  2.  
  3. Probiotics 2 - Application and practical aspects - (Ed.: Fuller R., Chapman & Hall, London, 1997) Antimutagenic and antitumour activities of lactic acid bacteris. Hosono A., Kitazawa H., and Yamaguchi T. p.89-132.



学術論文  Original Papers


骨格筋線維および筋細胞に関する研究 Studies on Muscle Biology

英文  in English

  1. Miyake M., Hayashi Shinichiro, Iwasaki S., Uchida T., Watanabe K, Ohwada S., Aso H., Yamaguchi T. (2010) TIEG1 negatively controls the myoblast pool indispensable for fusion during myogenic differentiation of C2C12 cells. Journal of Cellular Physiology in press. Abstract
     
  2. Miyake M., Hayashi S., Iwasaki S., Chao G., Takahashi H., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2010) Possible role of TIEG1 as a feedbaclk regulator of myostatin and TGF-β in myoblasts. Biochemical and Biophysical Research Communications 393(4): 762-766. Abstract
     
  3. Miyake M., Hayashi Shinichiro, Taketa Y., Iwasaki S., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2010) Myostatin down-regulates the IGF-2 expression via ALK-Smad signaling during myogenesis in cattle. Animal Science Journal. 81(2): 223-229. Abstract
     
  4. Muroya S., Watanabe K., Hayashi Shinichiro, Miyake M., Konashi S., Sato Y., Takahashi M., Kawahata S., Yoshikawa Y., Aso H., Chikuni K., Yamaguchi T. (2009) Muscle type-specific effect of myostatin deficiency on myogenic regulatory factor expression in adult double-muscled Japanese Shorthorn cattle. Animal Science Journal 80(6): 678-685. Abstract
     
  5. Hayashi Shinichiro, Miyake M., Watanabe K., Aso H., Hayashi Seigo, Ohwada S., Yamaguchi T. (2008) Myostatin preferentially down-regulates the expression of fast 2x myosin heavy chain in cattle. Proceedings of the Japan Academy, Series B 84(8): 354-362. Abstract
     
  6. Miyake M., Hayashi Shinichiro, Sato T., Taketa Y., Watanabe K., Hayashi S, Tanaka S., Ohwada S., Aso H., Yamaguchi T. (2007) Myostatin and MyoD family expression in skeletal muscle of IGF-1 knockout mice. Cell Biology International 31(10): 1274-1279 Abstract
     
  7. Nakamura Y.-N., Iwamoto H., Etoh T., Shiotsuka Y., Yamaguchi T., Ono Y., Tabata S., Nishimura S., Gotoh T. (2007) Three-dimensional observation of connective tissue of bovine masseter muscle under concentrate- and roughage-fed conditions by using immunohistochemical/confocal laser-scanning microscopic methods. Journal of Food Science 72(6): E375-E381. Abstract
     
  8. Nakamura Y., Iwamoto H., Yamaguchi T., Ono Y., Nakanishi Y., Tabata S., Nishimura S., Gotoh T. (2007) Three-dimensional reconstruction of intramuscular collagen networks of bovine muscle: A demonstration by an immunohistochemical/confocal laser-scanning microscopic method. Animal Science Journal 78(4): 445-447. Abstract
     
  9. Watanabe K., Hayashi Shinichiro, Nara H., Ohwada S., Aso H., and Yamaguchi T. (2004) Bovine Myoblast Differentiation. Tohoku Journal of Agricultural Research 55(1-2): 67-73.
     
  10. Hayashi Shinichiro, Aso H., Watanabe K., Nara H., Rose M.T., Ohwada S., and Yamaguchi T. (2004) Sequence of IGF-I, IGF-II, and HGF expression in regenerating skeletal muscle. Histochemistry and Cell Biology 122(5): 427-434. Abstract
     
  11. Nara H., Yoshizawa D., Aso H., and Yamaguchi T. (2001) Bovine myoblast differentiation during the myogenesis. Asian-Australasian Journal of Animal Science 14 (Special Issue): 100-105. Abstract
     
  12. Nara H., Imanaka T., and Yamaguchi T. (2000) Enhanced expression of acetylcholinesterase activity in bovine satellite cells treated with insulin-like growth factor I. Animal Science Journal 71(1): 63-70. Japanese Abstract, English Abstract
     
  13. Nishida H., Yamaguchi T., Sato K., Ohtsu H., and Akiba Y. (1997) Influence of prostaglandin E2 on chick myoblast differentiation during the myogenesis. Animal Science and Technology 68: 381-384.

和文  in Japanese

  1. 小梨 茂,佐藤洋一,鈴木暁之,渡邊康一,林 晋一郎,長谷川喜久,大池裕治,谷藤隆志,吉川恵郷,西田 朗,山口高弘 (2006) 日本短角種DM牛の初期発育様相.東北畜産学会報 56(1): 39-45.
     

総説・解説  Reviews (in Japanese)

  1. 内田 宏・渡邊康一・萬田富治・趙 国g・孫 龍生・全 炳台・山口高弘 (2008) 中国の黄牛と肉用牛生産,畜産の研究,4月号, 62(4): 449-460
     
  2. 内田 宏・渡邊康一・萬田富治・趙 国g・孫 龍生・全 炳台・山口高弘 (2008) 中国の黄牛とわが国の日本短角種の特性比較,畜産技術,1月号,631:
     
  3. 山口高弘,渡邊康一 (2007) 健康ビーフ生産に適した肉用牛造成の取り組み −次世代型のダブルマッスル形質をもつ日本短角種−,畜産コンサルタント8月号 512: 19-21.
     

国際学会報告  Reports in International Congress

  1. Watanabe K. and Yamaguchi T. (2009) Perspective of beef production in Japan and studies on muscle biology.“Sustainable Production of New Value Beef in Recent Future.” China-Japan joint Seminar: Improvement of beef production and beef quality. [Beijing, China] Invited Speaker
     
  2. Miyake M., Iwasaki S., Guozheng C., Takahashi H., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2009) Silencing TIEG1 expression promotes myotube formation through regulation of apoptosis. 49th Annual Meeting, The American Society for Cell Biology. [San Diego, U.S.A.] Poster
     
  3. Miyake M., Iwasaki S., Imai Y., Abe H., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2008) Effect of myostatin on IL-6 expression in skeletal muscle. The 13th AAAP Animal Science Congress 2008 [Hanoi, Vietnam] Poster
     
  4. Iwasaki S., Miyake M., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2008) Infuluence of myostatin on chemokine expressions in bovine skeletal muscle. The 13th AAAP Animal Science Congress 2008 [Hanoi, Vietnam] Poster
     
  5. Miyake M., Hayashi Shinichiro, Imai Y., Watanabe K., Ohwada S., Aso H., and Yamaguchi T. (2007) MSTN regulates IGF-2 but not IGF-1 expression during myogenesis of cattle. 2007 ADSA-PSA-AMPA-ASAS Joint Annual Meeting [San Antonio, TX, USA] Oral presentation
     
  6. Miyake M., Hayashi Shinichiro, Watanebe K., Ohwada S., Aso H., Yamaguchi T. (2006) No relation between myostain and igf-1 on skeletal muscle development. 12th AAAP Animal Science Congress 2006 [Busan, Korea] Poster
     
  7. Kido K., Watanabe K., Ohwada S., Yamaguchi M., Hayashi Y., Yamaguchi T. (2006) Myofiber types and capillary density in skeletal muscles of fattened japanese black steers after grazing. 12th AAAP Animal Science Congress 2006 [Busan, Korea] Oral Presentation
     
  8. Watanabe K., Konashi S., Satoh Y., Takahashi M., Kawahata S., Yoshikawa Y., Aso H., Yamaguchi T. (2006) Beef productivity of double-muscled japanese shorthorn cattle. 12th AAAP Animal Science Congress 2006 [Busan, Korea] Oral presentation
     
  9. Hayashi Shinichiro, Aso H., Ogasawara H., Miyake M., Watanabe K., Ohwada S. Yamaguchi T. (2006) Hyperplasia in DM cattle is due to failure of MSTN induction by HGF. 7th Joint Meeting of the Japan Society of Histochemistry and Cytochemistry and the US Histochemical Society [Hawaii, USA] Poster
     
  10. Hayashi Shinichiro, Watanabe K., Miura Y., Hayashi Seigo, Miyake M., Aso H., Ohwada S., Yamaguchi T. (2005) Myostatin regulates MyHC isoform expression during myoblast differentiation in cattle. ADSA-ASAS-CSAS 2005 Joint Annual Meeting (American Society of Animal Science, American Dairy Science Association, and Canadian Society of Animal Science) [Cincinnati, USA] Oral presentation Abstract 388
    J. Anim. Sci. Vol. 83, Suppl. 1/J. Dairy Sci. Vol. 88, Suppl. 1, 239.
     
  11. Watanabe K. and Yamaguchi T. (2005) Double muscling in Japanese shorthorn cattle. "Recent Advances in Animal Science in the AAAP region" Editorial Meeting for the BOOK of the History of AAAP [Sendai, Japan]
     
  12. Hayashi Shinichiro, Aso H., Watanabe K., Miura Y., Hayashi Seigo, Chikuni K., Suzuki T., Yamaguchi T. (2003) Myostatin regulates MyHC isoform expression during myogenic differentiation of myostatin deficient myoblasts. 43rd Annual Meeting, American Society for Cell Biology. Abstract [San Francisco, USA]
    Molecular Biology of the Cell, 14 (Suppl.): 311a
     
  13. Nakano T., Sato H., Yamaguchi T., Nara H., Watanabe K., Yamaguchi T., Sato M. (2002) Characteristics and in vitro proliferation of muscle-derived cells from rainbow trout. The 5th JSPS International Seminar Marine Products Processing Technology. "Empowerment of Marine Health Foods and Nutraceuticals Strengthening the Asian region" Abstract [Bogor, Indonesia]
     
  14. Nara H., Yoshizawa D., Aso H., and Yamaguchi T. (2001) Bovine myoblast differentiation during the myogenesis. International Symposium on New Challenges for Animal Science in a New Century , Session 1. Animal physiology and morphology [Sendai, Japan]
    アジア太洋州における動物生産科学の挑戦に関する国際シンポジウム
     
  15. Yamaguchi T., Kitazawa H., Nishida H., Ohtu H., Nara H., Ozutsumi K., Aso H., Watanabe K., and Suzuki A. (1997) Effects of growth factors on bovine myogenesis in vitro.  43rd International Congress of Meat Science and Technology, Congress Proceedings: 354-355. [New Zealand]
     
  16. Yamaguchi T., Ozutsumi K., Nishida H., Aso H., Watanabe K., Ohwada S., and Suzuki A. (1996) Enviromental influences upon bovine muscle differentiation in vitro. 8th AAAP Animal Science Congress, Proceedings Vol. 2: 566-567. [Chiba Makuhari Messe, Japan]

報告書

  1. 特許公開山口高弘,渡邊康一,佐藤 幹,三浦邦明,(東北大学・助川電気工業株式会社),特定の飼料を給与することを特徴とする家畜の飼育方法,特開2008-212149
     
  2. 山口高弘・麻生 久・渡邊康一・内田 宏・萬田富治・佐藤衆介 (2006-2007) 東北アジア地域の肉用牛遺伝資源の開拓とその活用技術の基盤形成に関する調査研究,文部科学省科学研究費補助金:基盤研究(B)海外学術:18405033
     
  3. 山口高弘・麻生 久・渡邊康一 (2005) 潜在的産肉能力の開拓による高品質赤肉産生・肉用牛資源の造成,文部科学省科学研究費補助金:基盤研究(C)企画調査:17628008
     
  4. 山口高弘・麻生 久・渡邊康一・長谷川喜久 (2005-2007) 骨格筋形成抑制因子、ミオスタチンの産肉調節作用の全容解明とその産肉性向上への活用,文部科学省科学研究費補助金:基盤研究(A):17208024
     
  5. 山口高弘,林 晋一郎,今中崇博,奈良英利,渡邊康一 (2002) 筋形成過程の骨格筋細胞でのミオシンアイソフォーム発現の制御.平成13年度・食肉に関する助成研究調査成果報告書,伊藤記念財団,要約
     
  6. 山口高弘,吉澤大輔,今中崇博,奈良英利,渡邊康一 (2001) 筋形成過程の骨格筋細胞でのミオシンアイソフォーム発現の制御.平成12年度・食肉に関する助成研究調査成果報告書,伊藤記念財団,要約
     
  7. 山口高弘,今中崇博 (2000) 筋形成過程の骨格筋細胞でのミオシンアイソフォーム発現の制御.平成11年度・食肉に関する助成研究調査成果報告書,伊藤記念財団,要約
     
  8. 鈴木敦士、鈴木 惇、服部昭仁、山口高弘、池内義英、西村敏英、伊藤肇躬 (1999) 筋肉の新規増殖因子ならびに新規活性物質と食肉の物性、官能特性および機能性との連関. 平成10年度食肉に関する助成研究調査
     
  9. 山口高弘,中村文彦,渡邊康一(1999)家畜骨格筋の筋管形促進因子の同定・分離と作用機序の解明,文部科学省科学研究費補助金研究成果報告書:基盤研究(B),1996〜1998年度:08456135
     
  10. 山口高弘(1992)食糧としての家畜(牛・豚)骨格筋細胞の応用に関する基礎研究,文部科学省科学研究費補助金研究成果報告書:一般研究(C),1990〜1991年度:02806049



乳腺および粘膜免疫に関する研究 Studies on Immunocytic Responses in Mammary Gland and Mucoepithelia

英文  in English

免疫系細胞 Immunocytes

  1. Tanaka S., Nagai Y., Noguchi Y., Miyake M., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2008) Differential cytokine expression in T cell subsets from bovine peripheral blood. Animal Science Journal 79(5): 597-604. Abstract
     
  2. Tanaka S., Miyazawa K., Kuwano A., Watanabe K., Ohwada S., Aso H., Nishida S., Yamaguchi T. (2008) Age-related changes inleukocytes and T cell subsets in peripheral blood of Japanese Black cattle. Animal Science Journal 79(3): 368-374 Abstract
     
  3. Tanaka S., Aso H., Miyazawa K., Nagai Y., Watanabe K., Ohwada S., Kobayashi J., Yamaguchi T. (2007) Differential cytokine gene expression in CD4+ and CD8+ T cell subsets of calves. Veterinary Immunology and Immunopathology 118(1-2): 84-91. Abstract
     
  4. Miyazawa K., Aso H., Honda M., Watanabe K., Ohwada S., Rose M.T., Yamaguchi T. (2006) Identification of dendritic cells from bovine peropheral blood. Research in Veterinary Science 81(1) 40-45. Abstract
     
  5. Tanaka S., Miyazawa K., Watanabe K., Ohwada S., Aso H., Yonai M., Saito N., Yamaguchi T. (2006) Comparison of T cell subsets between somatic cloned and normal cow. American Journal of Reproductive Immunology. 55(1): 28-35. Abstract

乳腺 Mammary Gland

  1. Komine K., Kuroishi T., Komine Y, Watanabe K., Kobayashi J., Yamaguchi T., Kamata S., and Kumagai K. (2004) Induction of nitric oxide production mediated by tumor necrosis factor alpha on staphylococcal enterotoxin C-stimulated bovine mammary gland cells. Clinical and Diagnostic Laboratory Immunology 11(1): 203-210. Abstract
     
  2. Asai K, Yamaguchi T., Kuroishi T., Komine Y., Kai K., Komine K., and Kumagai K. (2003) Differential gene expression of cytokine and cell surface molecules in T cell subpopulation derived from mammary gland secretion of cows. American Journal of Reproductive Immunology 50(6): 453-462. Abstract
     
  3. Kuroishi T., Komine K., Asai K., Kobayashi J., Watanabe K., Yamaguchi T., Kamata S., and Kumagai K. (2003) Inflammatory Responses of Bovine Polymorphonuclear Neutrophils Induced by Staphylococcal Enterotoxin C via Stimulation of Mononuclear Cells. Clinical and Diagnostic Laboratory Immunology, 10(6): 1011-1018. Abstract
     
  4. Yamaguchi T., Hiratsuka M., Asai K., and Kumagai K. (2000) A phenotype of mammary intra-epithelium lymphocytes (mIEL) in cows. Acta Histochemica et Cytochemica 33(1): 11-15. Abstract
     
  5. Asai K., Komine Y., Kozutsumi T., Yamaguchi T., Komine K., and Kumagai K. (2000) Predominant subpopulations of T lymphocytes in the mammary gland secretions during lactation and intraepithelial T lymphocytes in the intestine of dairy cows. Veterinary Immunology & Immunopathology. 73: 233-240. Abstract
     
  6. Yamaguchi T., Hiratsuka M., Asai K., Kai K., and Kumagai K. (1999) Differential distribution of T lymphocyte subpopulations in the bovine mammary gland during lactation. Journal of Dairy Science 82(7): 1459-1464. Abstract
     
  7. Asai K., Kai K., Rikiishi H., Sugawara S., Maruyama Y., Yamaguchi T., Ohta M., and Kumagai K. (1998) Variation in CD4+ T and CD8+ T lymphocyte subpopulations in bovine mammary gland secretions during lactating and non-lactating periods. Veterinary Immunology & Immunopathology 65(1): 51-61. Abstract
     
  8. Hiratsuka M., Yamaguchi T., Aoyagi T., and Suzuki A. (1996) Distribution of IgA-containing cells in the mucous layers of bovine teat with mastitis. Journal of Japanese Veterinary Medicine Association 49: 729-731.

粘膜上皮等 Mucoepithelia, etc.

  1. *Miyazawa K., *Hondo T., Kanaya T., Tanaka S., Takakura I., Itani W., Rose M.T., Kitazawa H., Yamaguchi T., Aso H. (2010) Characterization of newly established bovine intestinal epithelial cell line. Histochemistry and Cell Biology 133: 125-134. Abstract
    *:Contributed equally
     
  2. Kanaya T., Aso H., Miyazawa K., Kido T., Minashima T., Watanabe K., Ohwada S., Kitazawa H., Rose M.T., Yamaguchi T. (2007) Staining patterns for actin and villin distinguish M cells in bovine follicle-associated epithelium. Research in Veterinary Science 82(2): 141-149. Abstract
     
  3. Yasuda M., Ogawa T., Nasu T., Yamaguchi T., and Murakami T. (2005) Kinetics and distribution of bovine γδ T-lymphocyte in the intestine: γδ T cells accumulate in the dome region of Peyer's patch during prenatal development. Developmental & Comparative Immunology 29: 555-564. Abstract

和文 in Japanese

  1. 田中沙智・宮澤光太郎・永井康裕・桑野敦子・渡邊康一・大和田修一・麻生 久・西田 茂・児玉英樹・吉川恵郷・笠井幸治・山口高弘 (2007) 黒毛和種体細胞クローン牛の末梢血におけるT細胞サブセットの解析.東北畜産学会報 57(1): 13-18.
     
  2. 小峯優美子・小峯健一・貝 健三・板橋昌志・植松正巳・木舩厚恭・小林 仁・山口高弘・熊谷勝男 (2004) 初乳形成に向けた乾乳期乳腺免疫機構の変動とラクトフェリンの関与.日本畜産学会報 75(2): 205-212. Abstract

総説・解説  Reviews (in Japanese)

  1. 山口高弘(2005)乳腺免疫はどこまで分かっているか.臨床獣医 23(1): 21-26. (写真:6-7)
     
  2. 山口高弘(2000)乳牛の泌乳サイクルに伴う乳腺組織構築と乳腺免疫.家畜診療 47: 323-336.
     
  3. 熊谷勝男,浅井健一,山口高弘(1997)乳牛の乳腺免疫の研究−乳房炎防除の新方策を見出すために−.臨床獣医 15: 30-35.

国際学会報告  Reports in International Congress

  1. Tanaka S., Noguchi Y., Guo Y., Abe H., Suzuki R., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2008) Bovine γδ T cells display cytotoxic activity following IL-2 stimulation. The 4th Congress of the Federation of Immunology Societies of Asia-Oceania (FIMSA 2008) [Taipei, Taiwan] Poster
     
  2. Tanaka S., Hayashi Shinichiro, Taketa Y., Miyake M., Watanabe K., Ohwada S., Aso H., and Yamaguchi T. (2007) Comparative expression of activin receptor type IIB in bovine peripheral blood mononuclear cells. 2007 ADSA-PSA-AMPA-ASAS Joint Annual Meeting [San Antonio, TX, USA] Oral presentation
     
  3. Tanaka S., Miyazawa K., Watanabe K., Ohwada S., Aso H., Nishida S., Yamaguchi T. (2006) Age-related changes of leukocytes and T cell subsets in peripheral blood of Japanese Black cattle. 12th AAAP Animal Science Congress 2006 [Busan, Korea] Oral presentation
     
  4. Tanaka S., Miyazawa K., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2005) Cytokine expression of T cell subsets in bovine peripheral blood. ADSA-ASAS-CSAS 2005 Joint Annual Meeting (American Society of Animal Science, American Dairy Science Association, and Canadian Society of Animal Science) [Cincinnati, USA] Oral presentation Abstract 545
    J. Anim. Sci. Vol. 83, Suppl. 1/J. Dairy Sci. Vol. 88, Suppl. 1, 350.
     
  5. Miyazawa K., Honda M., Kobayashi J., Watanabe K., Ohwada S., Aso H., Davis W.C., Yamaguchi T. (2003) Phenotypes of dendritic cell in bovine peripheral blood and lymphoid organs. 43rd Annual Meeting, American Society for Cell Biology. [San Francisco, USA] Abstract
    Molecular Biology of the Cell, 14 (Suppl.): 381a.
     
  6. Nochi T., Yamaguchi T. (2000) Functional heterogeneity of mammary epithelial cells in cows. Pacific Congress on Milk Quality and Mastitis Control. Abstract [Nagano, Japan]
     
  7. Yamaguchi T., Nochi T. (2000) Kinetics of cytokine production in mammary gland of dairy cows during lactation cycle. Pacific Congress on Milk Quality and Mastitis Control. Abstract [Nagano, Japan]
     
  8. Yamaguchi T., Hiratuka M., Kai K., Asai K., Ohta M., and Kumagai K. (1998) Distribution of T cell subsets and B cells in bovine mammary gland. 8th World Conference on Animal Production, Proceedings Vol. I: 94-95. [Seoul, Korea]

報告書等

  1. 山口高弘 (2007) 体細胞クローン牛における免疫能の解析,「体細胞クローン動物安定生産技術の確立研究(農林水産省農林水産技術会議事務局)」,研究成果第444集 145-151, (2001-2005)
     
  2. 山口高弘 (2001-2005) 乳腺上皮の機能的多様性と感染抵抗性の解析,農業技術研究機構交付金プロジェクト乳房炎の発生機構の解明と防除技術の開発 成果概要集
    1. 山口高弘、佐々木幸乃、渡邊康一、麻生 久 (2005) 乳腺上皮の機能的多様性と感染抵抗性の解析,平成16年度主要成果
       
    2. 山口高弘、本多正史,宮澤光太郎、渡邊康一、麻生 久 (2004) 乳腺上皮の機能的多様性と感染抵抗性の解析,平成15年度主要成果
       
    3. 山口高弘、野地智法、渡邊康一、麻生 久 (2002) 乳腺上皮の機能的多様性と感染抵抗性の解析,平成13年度主要成果
  3. 山口高弘(2000)ウシ乳腺のTリンパ球サブセットの機能解析による乳腺免疫機構の解明,文部科学省科学研究費補助金研究成果報告書:萌芽研究,1998〜1999年度:10876061



内分泌器官に関する研究 Studies on Endcrine Organs


英文  in English

  1. Nagai Y., Aso H., Ogasawara H., Tanaka S., Taketa Y., Watanabe K., Ohwada S., Rose M.T., Kitazawa H., Yamaguchi T. (2008) Anterior pituitary progenitor cells express costimulatory molecule 4Ig-B7-H3 Journal of Immunology 181(10): 6073-6081. Abstract
     
  2. Nagai Y., Ogasawara H., Taketa Y., Aso H., Tanaka S., Kanaya T., Watanabe K., Ohwada S., Muneta Y., Yamaguchi T. (2008) Bovine anterior pituitary progenitor cell line expresses IL-18 and IL-18Rs. Journal of Neuroendocrinology 20(11): 1233-1241. Abstract
     
  3. Ogasawara H., Aso H., Nagai Y., Matumoto K., Okumura H., Tanaka S., Watanabe K., Ohwada S., Yamaguchi T. (2008) Presence of neuropeptide Y in somatotrophs of cattle. Domestic Animal Endocrinology 35(3): 274-280. Abstract
     
  4. Nagai Y., Ogasawara H., Taketa Y., Aso H., Watanabe K., Ohwada S., Muneta Y., Yamaguchi T. (2008) Expression of inflammatory related factors in porcine anterior pituitary derived cell line. Veterinary Immunology and Immunopathology 124(3-4): 201-208. Abstract
     
  5. Ogasawara H., Ohwada S., Nagai Y., Taketa Y., Matsuzaki M., Tanaka S., Watanabe K., Aso H., Yamaguchi T. (2008) Localization of leptin and leptin receptor in the bovine adenohypophysis. Domestic Animal Endocrinology 35(1): 8-15. Abstract
     
  6. Taketa Y., Nagai Y., Ogasawara H., Hayashi S., Miyake M., Tanaka S., Watanabe K., Ohwada S., Aso H., Yamaguchi T. (2008) Differential expression of myostatin and its receptor in the porcine anterior pituitary gland. Animal Science Journal 79(3): 382-390. Abstract
     
  7. Nagai Y., Watanabe K., Aso H., Ohwada S., Muneta Y., Yamaguchi T. (2006) Cellular localization of IL-18 and IL-18 receptor in pig anterior pituitary gland. Domestic Animal Endocrinology 30(2): 144-154. Abstract
     
  8. Nagai Y., Nochi T., Watanabe K., Watanabe Keisuke, Aso H., Kitazawa H., Matsuzaki M., Ohwada S., Yamaguchi T. (2005) Localization of Interleukin-18 and its receptor in somatotrophs of the bovine anterior pituitary gland. Cell and Tissue Research 322(3): 455-462. Abstract.
     
  9. Matsuzaki M., Sato T., Watanabe K., Shiba N., Tsuneishi E., and Yamaguchi T. (2003) Immunohistochemical detection of pituitary transcription factor-1 in paraffin sections of bovine adenohypophysis after wet heat-induced antigen retrieval. Animal Science Journal 74(2): 137-143. Abstract
     
  10. Matsuzaki M., Sato T., Morita S., Shiba N., Tsuneishi E., Hara S., Ozutsumi K. and Yamaguchi T. (2001) Pulsatile growth hormone secretion, circulating insulin-like growth factor-1 concentration and cellular density of somatotrophs differ between Wagyu and Holstein steers. Animal Science 73: 425-432. Abstract
     
  11. Matsuzaki M., Sato T., Shiba N., Hara S., Tsuneishi E., Yamaguchi T. (2001) Effects of restricted concentrate feeding during the early growing phase on growth performance, carcass characteristics and the somatotropic axis in Holstein steers. Animal Science Journal. 72(6): 483-493. Abstract
     
  12. Sato T., Yamaguchi T., Matsuzaki M., Satoh T., and Suzuki A. (1999) Mammosomatotrophs develop within mammotroph clusters in bovine adenohypophysis. Tissue & Cell 31: 499-504. Abstract
     
  13. Sato T., Yamaguchi T., Matsuzaki M., and Suzuki A. (1999) Somatotrophs and mammotrophs in adenohypophysis of Japanese black steers: an immunohistochemical and morphological study. Animal Science Journal 70: 329-335.
     
  14. Yamaguchi T., Ide Y., Sato T., Satoh T., and Matsuzaki M. (1999) Differentiation of mammosomatotrophs in swine adenohypophysis. Acta Histochemica et Cytochemica 32: 315-320. Abstract

  15.  
  16. Yamaguchi T. (1994) Ultracytochemical localization of alkaline phosphatase in swine gonadotropic cells. Journal of Veterinary Medical Science. 56(3): 529-533.
     
  17. Yamaguchi T. (1993) Alkaline phosphatase activity in the gonadotropic cells of swine adenohypophysis. Acta Histochemica et Cytochemica. 26(5): 365-371.

国際学会報告  Reports in International Congress

  1. Ogasawara H., Aso H., Nagai Y., Akasaka D., Sato H., Watanabe K., Ohwada S., Yamaguchi T. (2007) Cellular localization of neuropeptide Y in adenohypophysis. The 6th Congress of the Asia and Oceania Society for Comparative Endocrinology [NBU, Siliguri, India]
     
  2. Nagai Y., Aso H., Ogasawara H., Tanaka S., Watanabe K., Ohwada S., and Yamaguchi T. (2007) Characters and functions of anterior pituitary progenitor cells that are identifi ed by a novel monoclonal antibody. 2007 ADSA-PSA-AMPA-ASAS Joint Annual Meeting [San Antonio, TX, USA] Oral presentation
     
  3. Nagai Y., Ogasawara H., Aso H., Taketa Y., Yamaguchi T. (2006) An Established Anterior Pituitary Progenitor Cells (BPC-1) Could Produce Several Inflammatory Cytokines by the Stimulation through Its Il-18 Receptors. 46th Annual Meeting, The American Society for Cell Biology. [San Diego, U.S.A.] Poster Abstract
     
  4. Ogasawara H., Ohwada S., Nagai Y., Taketa Y.,Watanabe K., Aso H., Yamaguchi T. (2006) Expression of leptin and leptin receptor in bovine adenohypophyseal cells. 7th Joint Meeting of the Japan Society of Histochemistry and Cytochemistry and the US Histochemical Society [Hawaii, USA] Poster
     
  5. Taketa Y., Aso H., Nagai Y., Ogasawara, H., Hayashi Shinichiro, Miyake M., Watanabe K., Ohwada S. Yamaguchi T. (2006) Differential Expression of Myostatin and activin receptor type IIB in the bovine anterior pituitary gland. 7th Joint Meeting of the Japan Society of Histochemistry and Cytochemistry and the US Histochemical Society. [Hawaii, USA] Poster
     
  6. Nagai Y., Ogasawara H., Taketa Y., Aso H., Watanabe K., Ohwada S., Yamaguchi T. (2006) A stem/progenitor cell line derived from bovine anterior pituitary exhibits an immunomodulator function. 1st Conference of Asian Association of Veterinary Anatomists (Joint Meeting with JAVA) [Tsukuba, Japan] Poster
     
  7. Nagai Y., Watanabe K., Aso H., Ohwada S., Yamaguchi T. (2005) Localization of Interleukin-18 and its receptor in somatotrophs of bovine anterior pituitary gland. ADSA-ASAS-CSAS 2005 Joint Annual Meeting (American Society of Animal Science, American Dairy Science Association, and Canadian Society of Animal Science) [Cincinnati, USA]
     
  8. Watanabe Keisuke, Yamaguchi T., Sato T., Watanabe K., Ohwada S., Aso H. (2003) Cellular localization of orexin and orexin receptors (OXRs) in bovine adenohypophysis. 43rd Annual Meeting, The American Society for Cell Biology. [San Francisco, U.S.A.] Abstract
    Molecular Biology of the Cell, 14 (Suppl.): 125a
     
  9. Yamaguchi T., Sato T., Matsuzaki M, Watanabe K., Ohwada S., and ASO H. (2002) Galanin Expression in ACTH Cells of Bovine Adenohypophysis. 42nd Annual Meeting, The American Society for Cell Biology. [San Francisco, U.S.A.] Abstract.
    Molecular Biology of the Cell, 13 (Suppl.): 490a
     
  10. Sato T., Horiguchi E., Satoh T., and Yamaguchi T. (2000) Ultracytochemical localization of galanin in corticotrophs. 11th International Congress of Histochemistry and Cytochemistry. Abstract booklet 124-125. [York, U.K.]
    Best Young Researcher Award: Takahiro SATO
     
  11. Matsuzaki M., Sato T., Morita S., Shiba E., Tsuneishi E., Hara S., Ozutsumi K., and Yamaguchi T. (1998) Characteristics of somatotropic axis in Wagyu. 3rd International Conference on Farm Animal Endocrinology. Biotechnology, Agronomy Society and Environment. Vol. 2. Special Issue: 26. [Brussels, Belgium]
     
  12. Matsuzaki M., Tsuneishi E., Takada R., Kaji Y., Shiba N., Hara S., Ozutsumi K., and Yamaguchi T. (1997) Age-related changes of growth hormone secretion and somatotroph function in Japanese Black Steers. British Society of Animal Science, the Society's Annual Meeting. Proceedings of the British Society of Animal Science. 52.


報告書

  1. 山口高弘・渡邊康一 (2004-2005) ミオスタチンの新規GH分泌調節作用の解明,文部科学省科学研究費補助金:萌芽研究:16658106
     
  2. 山口高弘,西森克彦,麻生 久,渡邊康一(2004)ウシの摂食調節神経ペプチドのソマトトロフ軸に対する作用機序の解明,文部科学省科学研究費補助金研究成果報告書:基盤研究(B),H13〜H15年度:13460122

     
  3. 山口高弘,井出陽一 (1997) 豚の成長,肥育と下垂体前葉細胞機能との関連に関する研究.平成8年度・食肉に関する助成研究調査成果報告書,伊藤記念財団
     
  4. 山口高弘,井出陽一 (1996) 豚の成長,肥育と下垂体前葉細胞機能との関連に関する研究.平成7年度・食肉に関する助成研究調査成果報告書,伊藤記念財団