Chemistry and Life Science

Analytical Bioorganic Chemistry

Introduction

We have been interested in chemistry and biology of natural products.
Currently, the glycopeptide antibiotics vancomycin is our major research target. Vancomycin is a clinically important medicine, which is considered the drug of last resort in the treatment of multi-resistant Gram-positive bacteria. We have already developed compounds that are quite effective against vancomycin-resistant bacteria. We are also studying, cellular functions of endogenous 8-nitro-cGMP, and chemical synthesis of biologically active natural products.

8-Nitro-cGMP: the first endogenous cGMP derivative

URL

https://www.agri.tohoku.ac.jp/bunseki/index-j.html

Keywords

Staff