Fermentation Microbiology


The koji molds including Aspergillus oryzae have been long used in traditional Japanese fermentation industries and thus are recognized as one of the most important industrial microorganisms in Japan. In this laboratory, we aim to promote the research on molecular biotechnology in the koji molds through studies on regulatory mechanisms for industrially important gene expression and on development of novel cellular functions by genetic engineering techniques.
1. Regulatory mechanisms for hydrolytic gene expression in the koji molds and their related species.
2. Development of high yield production systems for industrially valuable proteins and metabolites using Aspergillus oryzae as a host.
3. Construction of gene knockout library of Aspergillus oryzae and its application to molecular studies.