【Development of immunobiotic selection and evaluation system of livestock and human model and elucidation of certain immunoregulatory mechanisms】

    As the global spread of infectious diseases in livestock as well as in humans accelerates, there is a great need for a dramatic improvement in livestock healthy rearing technology through a third type of infectious disease control that does not rely on antimicrobials in addition to vaccines and hygiene management. In our study, we aim to contribute to the reduction of infectious disease outbreaks by constructing an effective immunobiotic selection and evaluation system in vitro, and it aims at contributing to the reduction of the infectious disease incidence from the construction of the anti-disease reinforcement base. Specifically, we are selecting and evaluating immunobiotics that are effective in reducing rotavirus infection. And, the verification in vivo is also promoted on the usefulness of the polysaccharide producing immunobiotics in the livestock healthy strategy. We are also analyzing candidate active factors (immunogenics (postbiotics) ) concerning the antiviral immunity in the immunobiotics based on the comparative genome analysis, and are promoting verification using molecular biological methods. In addition, we are developing overseas collaborative research on immunobiotics useful for reducing coronavirus infection.

Immunobiotics selection and evaluation system

Antiviral Immunobiotics