東北大学 大学院農学研究科

 酵 素 化 学 分 野 Laboratory of ENZAYMOLOGY
発表論文

Publications 2023

Suzuki, R.; Takahashi, H.; Yoshida, C.; Hidaka, M.; Ogawa, T*.; Futai, E*.  Specific Mutations near the Amyloid Precursor Protein Cleavage Site Increase γ-Secretase Sensitivity and Modulate Amyloid-β Production. Int. J. Mol. Sci. 2023, 24, 3970. https://doi.org/10.3390/ijms24043970

 

Publications 2022

Watari H., Kageyama H., Masubuchi N., Nakajima H., Onodera K., Focia P. J., Oshiro T., Matsui T., Kodera Y., Ogawa T., Yokoyama T., Hirayama M., Hori K., Freymann D. M., Komatsu N., Araki M., Tanaka Y, Sakai R.  A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation. Nature Commun. 13, 7262 (2022). https://doi.org/10.1038/s41467-022-34921-2

 

Isomoto A*, Shoguchi E, Hisata K, Inoue J, Inaba K, Satoh N, Ogawa T* and Shibata H*.  Active expression of genes for protein modification enzymes in the venom gland of habu snakes revealed by comprehensive transcriptomic analyses.  Toxins 2022; 14(5), 300. https://www.mdpi.com/2072-6651/14/5/300/htm

 

Hidaka M, Miyashita S, Yagi N, Hoshino M, Kogasaka Y, Fujii T, Kanayama Y. High-Resolution X-ray Phase-Contrast Imaging and Sensory and Rheometer Tests in Cooked Edamame. Foods. 2022; 11(5):730. https://doi.org/10.3390/foods11050730

 

Ghanem N, Kanagami N, Matsui T, Takeda K, Kaneko J, Shiraishi Y, Choe C A, Uchikubo-Kamo T,  Shirouzu M, Hashimoto T, Ogawa T, Matsuura T, Po-Ssu H, Yokoyama T, and Tanaka Y.  Chimeric mutants of staphylococcal hemolysin, which act as both one‐component and two‐component hemolysin, created by grafting the stem domain. FEBS J. (2022). https://doi.org/10.1111/febs.16354

 

Watanabe H, Yoshida C, Hidaka M, Ogawa T, Tomita T, Futai E*. Specific Mutations in Aph1 Cause γ-Secretase Activation. Int. J. Mol. Sci., 23(1):507 (2022). https://doi.org/10.3390/ijms23010507

 

Publications 2021

Watari H., Kageyama H., Masubuchi N., Nakajima H., Onodera K., Focia P. J., Oshiro T., Matsui T., Kodera Y., Ogawa T., Yokoyama T., Hirayama M., Hori K., Freymann D. M., Komatsu N., Araki M., Tanaka Y, Sakai R.

Hidden pathway for cytokine receptor activation: Structural insights into a marine sponge-derived lectin that activates the thrombopoietin receptor via recognition of the fucose moiety.

bioRxiv 2021.10.29.466502; doi: https://doi.org/10.1101/2021.10.29.466502  Preprint

 

Ogawa T*, Tobishima Y, Kamata S, Matsuda Y, Muramoto K, Hidaka M, Futai E, Kuraishi T, Yokota S, Ohno M, Hattori S

Focused proteomics analysis of habu snake (Protobothrops flavoviridis) venom using antivenom-based affinity chromatography reveals novel myonecrosis-enhancing activity of thrombin-like serine proteases.

Frontiers in Pharmacology 12, 3054 (2021). doi: 10.3389/fphar.2021.766406.

 

Ogawa T*, Sato R, Naganuma T, Liu K, Sato S, Sakaue S, Osada M, Yoshimi K, Muramoto K

Diversified biomineralization roles of Pteria penguin pearl shell lectins as matrix proteins.

Int. J. Mol. Sci., 22(3), 1081 (2021) https://doi.org/10.3390/ijms22031081

 

Ishida K, Tsukamoto Y, Horitani T, Ogawa T, Tanaka Y

Biochemical properties of CumA multicopper oxidase from plant pathogen, Pseudomonas syringae. Bioscience, Biotechnology, and Biochemistry, 85(9):1995-2002 (2021) https://doi.org/10.1093/bbb/zbab123

 

Maeno Y, Kotaki Y, Terada R, Hidaka M, Cho Y., Konoki K., Yotsu-Yamashita M., Preparation of domoic acid anologues using a bioconversion system, and their toxicity in mice., Org. Biomol. Chem., 19:7894-7902 (2021) https://doi.org/10.1039/D1OB01378E

 

Publications 2020

Urano Y, Takahachi M, Higashiura R, Fujiwara H, Funamoto S, Imai S, Futai E, Okuda M, Sugimoto H, Noguchi N

Curcumin Derivative GT863 Inhibits Amyloid-Beta Production via Inhibition of Protein N-Glycosylation

Cells 2020, 9(2), 349; https://doi.org/10.3390/cells9020349

 

Oizumi Y., Hirakakiuchi I., Muramoto K., Tanaka Y., and Ogawa T.*

Identification of Soy Protein Candidates Involved in the Derivation of Anti-cancer Peptide, Lunasin, from 2S albumin.

Soy Protein Res,22, 112-117(2020).

 

Ogawa T*,  Shibata H.

Venomics Study of Protobothrops flavoviridis Snake: How Venom Proteins Have Evolved and Diversified?

Med. Toxicol. ISBN 978-1-83880-278-3 (2020): https://www.intechopen.com/online-first/venomics-study-of-em-protobothrops-flavoviridis-em-snake-how-venom-proteins-have-evolved-and-diversi

 

Isomoto A, Hisata K, Inoue J, Shoguchi E, Satoh N, Ogawa T,  Shibata H

Identification of non-venom protein genes highly expressed in the venom gland of Habu (P. flavoviridis) and their potential contribution to the quality control of venom proteins.

Toxicon 177, S53 (2020).

 

Adachi K, Yamada T, Ishizuka H, Oki M, Tsunogae S, Shimada N, Chiba O, Orihara T, Hidaka M, Hirokawa T, Odagi M, Konoki K, Yotsu-Yamashita M, Nagasawa K.

Synthesis of C12-Keto Saxitoxin Derivatives with Unusual Inhibitory Activity Against Voltage-Gated Sodium Channels.

Chemistry (Weinheim an der Bergstrasse, Germany) 26(9) 2025-2033 (2020).

 

Publications 2019

Ogawa T., Oda-Ueda N., Hisata K., Nakamura N., Chijiwa T., Hattori S., Isomoto A., Yugeta H., Yamasaki S., Fukumaki Y., Ohno M, Satoh N., Shibata H.

Alternative mRNA Splicing in Three Venom Families Underlying a Possible Production of Divergent Venom Proteins of the Habu Snake, Protobothrops flavoviridis

Toxins, 11, 581 (2019); https://doi.org/10.3390/toxins11100581

 

Ogawa T., Sato R., Naganuma T., Liu K., Lakudzala AE, Muramoto K., Osada M., Yoshimi K., Hiemori K., Hirabayashi J., Tateno H.

Glycan Binding Profiling of Jacalin-Related Lectins from the Pteria Penguin Pearl Shell.

Int. J. Mol. Sci., 20, 4629 (2019); https://doi.org/10.3390/ijms20184629

 

Futai E

Advanced yeast models of familial Alzheimer disease expressing FAD-linked presenilin to screen mutations and γ-secretase modulators

Yeast Systems Biology, Methods in Molecular Biology, vol 2049: 403-417 (2019)

 

Imai S, Cai T, Yoshida C, Tomita T, Futai E

Specific mutations in presenilin 1 cause conformational changes in γ-secretase to modulate amyloid β trimming

Journal of Biochemistry 165 (1), 37-46 (2019)

 

Hashimoto T., Ye Y., Matsuno A., Ui M., Ogawa T., Matsui T., Tanaka Y. *

Protein encapsulation in the hollow space of hemocyanin crystals containing a covalently conjugated ligand.

Biochem. Biophys. Res. Commun., 514 (1), 31-36 (2019).

 

Matsui T., Kamata S., Ishii K., Maruno T., Ghanem N., Uchiyama S., Kato K., Suzuki A., Oda-Ueda N., Ogawa T., Tanaka Y. *

SDS-induced oligomerization of Lys49-phospholipase A2 from snake venom.

Sci. Rep.9, Article number 2330 (2019). DOI: https://doi.org/10.1038/s41598-019-38861-8

 

Hashimoto T., Ye Y., Matsuno A., Ohnishi Y., Kitamura A., Kinjo M., Abe S., Ueno T., Yao M., Ogawa T., Matsui T., Tanaka Y. *

Encapsulation of biomacromolecules by soaking and co-crystallization into porous protein crystals of hemocyanin. Biochem. Biophys. Res. Commun., 509, 577-584(2019).

 

Nakae S., Shionyu M., Ogawa T. *, Shirai T. *

Crystallization of Pearl Biomineralization Protein in Microgravity Environments.

Int. J. Microgravity Sci. Appl., 36 (1) 360105 (2019).  DOI: 10.15011//jasma.36.360105

 

柴田弘紀, 小川智久*「ベノミクス研究」の最前線:動物毒は,どのように進化してきたのか?

化学と生物,  57 (5), 289-295 (2019)

 

日高將文、七谷圭 放射光利用の手引き. アグネ技術センター(2019)

 

Publications 2018

Shibata H.*, Chijiwa T., Oda-Ueda N., Nakamura H., Yamaguchi K., Hattori S., Matsubara K., Matsuda Y., Yamashita A., Isomoto A., Mori K., Tashiro K., Kuhara S., Yamasaki S., Fujie M., Goto H., Koyanagi R., Takeuchi T., Fukumaki Y., Ohno M., Shoguchi E., Hisata K., Satoh N.*, and Ogawa T.*

The habu genome reveals accelerated evolution of venom protein genes.

Sci. Rep. 8, 10.1038/s41598-018-28749-4(2018).

https://www.nature.com/articles/s41598-018-28749-4 (press release1, press release2 有)

 

Nakae S., Shiny M., Ogawa T. *, Shirai T. *

Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization.

PROTEINS: Structure, Function, and Bioinformatics 86 (6), 644-653(2018). https://doi.org/10.1002/prot.25491. (掲載号の表紙デザインに採用)

 

Hidaka M, Okabe E, Hatakeyama K, Zook H, Uchida C, Uchida T*

Fluorescent resonance energy transfer -based biosensor for detecting conformational changes of Pin1.

Biochem. Biophys. Res. Commun., 505(2), 399-404 (2018).

 

Hidaka M, Kosaka K, Tsushima S, Uchida C, Takahashi K, Takahashi N, Tsubuki M, Hara Y, Uchida T*

Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin1.

Biochem. Biophys. Res. Commun., 499(3), 681-687 (2018).

 

Publications 2017

Ogawa T.*, Hirakakiuchi I., Tsubono M., Sato R., Yukawa M., Muramoto K.

Molecular mechanism of derivation of anti-cancer peptide, lunasin, from 2S albumin, and its application to the processed foods of soybean.

Soy Protein Res,20, 47-51 (2017).

 

Guan, J. Takai R., Toraya K., Ogawa T., Muramoto K.*, Mori S., Ishikawa D., Fujii, T, Hyun Chi F., and Cho S-J. (2017) Effects of Alkaline Deamidation on the Chemical Properties of Rice Bran Protein.

Food Sci. Technol Res.,23 (5), 697-704(2017).

 

Nakata H., Lin, C-Y., Abolhassani M., Ogawa T., Tateno H., Hirabayashi J., Muramoto K.*

Isolation of Rice Bran Lectins and Characterization of Their Unique Behavior in Caco-2 Cells.

Int. J. Mol. Sci., 18(5), 1052 (2017).

 

Kuroishi T.*, Bando K., Tanaka Y., Shishido K., Kinbara M., Ogawa T., Muramoto K., Endo Y., Sugawara S.

CXCL4 is a novel nickel-binding protein and augments nickel allergy. Clin Exp Allergy.  47(8), 1069-1078(2017).

 

Katow, H., Kanaya, T., Ogawa, T., Egawa, R., Yawo, H.*

Regulation of axon arborization pattern in the developing chick ciliary ganglion-possible involvement of caspase 3.

Dev. Growth Differ., 59(3):115-128(2017).

 

小川智久* “毒タンパク質・ペプチドの分子進化と機能獲得について:神経毒コノトキシンを中心に”

Clinical Neuroscience 35 (12), 1457-1461 (2017).

 

Publications 2016-2011

Yamazaki T, Ogawa T, Muramoto K, Nakahigashi J, Takeuchi A and Ueda H: Isolation and Biochemical Characterization of Mucus Proteins of Japanese Bunching Onion (Allium fistulosum) Green Leaves.

Food Sci. Technol. Res., 22 (2), 235-243 (2016).

 

Yonemura Y, Futai E, Yagishita S, Kaether C, Ishiura S

Specific combinations of presenilins and Aph1s affect the substrate specificity and activity of γ-secretase

Biochem. Biophys. Res. Commun., 478 (4), 1751-1757 (2016)

 

Futai E, Osawa S, Cai T, Fujisawa, T Ishiura S, Tomita T

Suppressor mutations for presenilin 1 familial Alzheimer disease mutants modulate γ-secretase activities

Journal of Biological Chemistry 291 (1), 435-446 (2016)

 

Futai E

Functional properties of gamma-secretase in the yeast reconstitution system

生化学 88 (2), 215-219 (2016)

 

Hidaka M, Gotoh A, Shimizu T, Minamisawa K, Imamura H, Uchida T

Visualization of NO3⁻/NO2⁻ Dynamics in Living Cells by Fluorescence Resonance Energy Transfer (FRET) Imaging Employing a Rhizobial Two-component Regulatory System.

J. Biol. Chem., 291(5), 2260-2269 (2016).

 

E. Kenmochi, S. Rashel Kabir, T. Ogawa, R. Naude, H. Tateno, J. Hirabayashi and *K. Muramoto

Isolation and Biochemical Characterization of Apios Tuber Lectin

Molecules, 20 (1), 987-1002 (2015).

 

Y. OHASHI, R. ONUMA, T. NAGANUMA, T. OGAWA, R. NAUDE, K. NOKIHARA and K. MURAMOTO:

Antioxidant Properties of Tripeptides Revealed by a Comparison of Six Different Assays.

Food Sci. Technol. Res., 21, 695-704 (2015).

 

Ryo Nemoto, Shintaro Yamamoto, Tomohisa Ogawa, Ryno Naude and Koji Muramoto: Effect of Chum Salmon Egg Lectin on Tight Junctions in Caco-2 Cell Monolayers. Molecules, 20, 8094-8106 (2015); doi:10.3390/molecules20058094

 

Onodera T, Futai E, Kan E, Abe N, Uchida T, Kamio K, Kaneko J

Phosphatidylethanolamine plasmalogen enhances the inhibiting effect of phosphatidylethanolamine on γ-secretase activity

Journal of Biochemistry 157 (5), 301-309 (2015)

 

小川智久 ”マベ真珠バイオミネラリゼーション:マトリックスタンパク質による結晶界面制御” Colloid and Interface Communication (C & I Commun), 40 (1), 27-30 (2015).

 

Naganuma, T., Hoshino, W., Shikanai, Y., Sato, R., Liu, K., Sato, S., Muramoto, K., Osada, M., Yoshimi, K., Ogawa, T.* (2014) Novel Matrix Proteins of Pteria penguin Pearl Oyster Shell Nacre Homologous to the Jacalin-Related β-Prism Fold Lectins. PLoS ONE 9(11): e112326. doi:10.1371/journal.pone.0112326. (featured in Nature Chemical Biology’s News & Views, January Issue 2015)

 

Odei-Addo, F., Frost, C., Smith, N., Ogawa, T., Muramoto, K., Oliva, MLV,  Gráf, L., Naude, R.* (2014) Biochemical characterization of Acacia schweinfurthii serine proteinase inhibitor. J. Enzyme Inh. Med. Chem. 29, 633-638.

 

Sánchez C, Itakura M, Okubo T, Matsumoto T, Yoshikawa H, Gotoh A, Hidaka M, Uchida T, Minamisawa K.*

The nitrate-sensing NasST system regulates nitrous oxide reductase in Bradyrhizobium japonicum.

Environ Microbiol.,16(10), 3263-3274 (2014).

 

Mori T, Hidaka M, Ikuji H, Yoshizawa I, ToyoharaH, Okuda T, Uchida C, Asano T, Yotsu-Yamashita M, Uchida T.*

A High-Throughput Screen for Inhibitors of the Prolyl Isomerase, Pin1, Identifies a Seaweed Polyphenol that Reduces Adipose Cell Differentiation.

Biosci. Biotechnol. Biochem.,78(5), 832-838 (2014).

 

Takahashi K, Shimizu T, Kosaka K, Hidaka M, Uchida C, Uchida T*

Role of Prolyl Isomerase Pin1 in Pathogenesis of Diseases and Remedy for the Diseases from Natural Products.

Curr Drug Targets,15(10), 973-981(2014).

 

Ogawa, T.* and Shirai, T. (2014) Chapter 44:  Tracing Ancestral Specificity of Lectins: Ancestral Sequence Reconstruction Method as a New Approach in Protein Engineering. In: Lectins Methods and Protocols Part4, Method in Molecular Biology, (Ed. by Hirabayashi, J.) p.p. 539-551, Humana Press ISSN: 1064-3745, 1200:539-51. DOI: 10.1007/978-1-4939-1292-6_44

 

Yamamoto, S., Tomiyama, M., Nemoto, R., Naganuma, T., Ogawa, T., Muramoto, K. (2013) Effects of Food Lectins on the Transport System of Human Intestinal Caco-2 Cell Monolayers. Biosci. Biotech. Biochem., 77 (9) 1917-1924.

 

Watanabe, Y., Chang, Y.-H. Nakamura, O., Naganuma, T., Ogawa, T., Muramoto, K. (2013) Rhamnose-binding lectins induce respiratory burst activity in macrophage cells from rainbow trout. Fisheries Sci., 10.1007/s12562-013-0624-7.

 

Gotoh A, Hidaka M, Hirose K, Uchida T

Gas7b (growth arrest specific protein 7b) regulates neuronal cell morphology by enhancing microtubule and actin filament assembly

J. Biol. Chem., 288(48), 34699-34706 (2013).

 

Koyama Y, Hidaka M, Nishimoto M, Kitaoka M

Directed evolution to enhance thermostability of galacto-N-biose/lacto-N-biose I phosphorylase.

PEDS, 26(11), 755-761(2013).

 

Ogawa, T.* and Shirai, T. (2013) Experimental molecular archeology: reconstruction of ancestral mutants and evolutionary history of proteins as a new approach in protein engineering.  In: Protein Engineering -Technology and Application (Ed. by T. Ogawa) InTech, ISBN 980-953-307-520-9

 

Y. Watanabe, T. Naganuma, T. Ogawa, and K. Muramoto (2013) Chapter 4: Lectins of marine origin and their clinical applications.  In: Antitumor potential and other emerging medicinal properties of natural compounds (Ed. by E.F. Fang and T.B. Ng) Springer, ISBN 978-94-007-6213-8.DOI 10.1007/978-94-007-6214-5.

 

H. Shibata · M. Yamamoto · N. Tuckett · T. Ogawa · K. Mori · T. Chijiwa · S. Hattori · N. Oda-Ueda · S. Kuhara · M. Ohno · Y. Fukumaki.  Whole genome sequencing of Asian pit viper, Habu, Protobothrops flavoviridis and its repetitive landscape.

GENES & GENETIC SYSTEMS 88(6):370-370 (2013)

 

Yoshimura S, Komatsu M, Kaku K, Hori M, Ogawa T, Muramoto K, Kazama T, Ito Y, Toriyama K. (2012) Production of transgenic rice plants expressing Dioscprea batatus tuber lectin 1 to confer resistance against brown plant hopper.

Plant Biotechnol. 29: 501-504.

 

M. Watanabe, O. Nakamura, K. Muramoto, and T. Ogawa (2012)

Allosteric regulation of the carbohydrate-binding ability of a novel conger Eel galectin by D-mannoside

J. Biol. Chem.  287 (37) 31061-31072.

 

Nakamura O., Watanabe M., Ogawa T., Muramoto K., Ogawa K., Tsutsui S., and Kamiya H (2012)

Galectins in the abdominal cavity of conger eel, Conger myriaster, participate in the cellular encapsulation of parasitic nematode by host cells

Fish and Shellfish Immunology 33, 780-787.

 

Bhangoo, S., Copits, B., Nakamura, Y., Frausto S., Robbins J., Gill M.B., Smith, C., Ogawa, T., Muramoto K., Sakai, R. and Swanson, G.T.* (2012) Modulation of AMPA and kainate receptors by galectins. The FASEB Journal. 26:10482.

 

Hidaka, M., Koga, T., Kiyota, H., Horiguchi, T., Shi, Q-W., Hirose, K., Uchida, T.

Relationship between the Structures of Taxane Derivatives and Their Microtubule Polymerization Activity.

Biosci. Biotechnol. Biochem.,76(2),349-352 (2012).

 

Nishimoto, M., Hidaka, M., Nakajima, M., Fushinobu, S., Kitaoka, M.

Identification of amino acid residues that determine the substrate preference of 1,3-beta-ga1actosyl-N-acetylhexosamine phosphorylase.

J. Mol. Catal. B-Enzym.,74(1-2), 97-102(2012).

 

Yamashita J., Chen H.-M., Naganuma T., Ogawa T., and Muramoto K. (2011)

Changes of functional components and antioxidative activity in the process of fermentation of soybeans.

ACS Symposium Series. 1059  In Chemistry, Texture, and Flavor of Soy; Ed by Cadwallader, K. et al; Chapter 10:  p155-169.

 

Krause J., Tshidino S. C., Ogawa T., Watanabe Y., Oosthuizen V., Somai B., Muramoto K., Naudé R. J.  (2011)

Purification and partial characterization of ostrich skeletal muscle cathepsin D and its activity during meat maturation.

Meat Science 87: 196-201.

 

Konno A, Kitagawa A, Watanabe M, Ogawa T, Shirai T (2011)

Tracing protein evolution through ancestral structures of fish galectin.
Structure 19 (5): 711-721. (nominated by the Faculty of 1000)

 

Ogawa T, Watanabe M, Naganuma T and Muramoto K (2011)
Diversified carbohydrate-binding lectins from marine resources.
Journal of Amino Acids, 2011: Article ID 838914, 20 pages doi:10.4061/2011/838914

 

Mori, T.,  Hidaka, M.,  Lin, Y-C., Yoshizawa, I., Okabe, T., Egashira, S., Kojima, H., Nagano, T., Koketsu, M., Takamiya, M., Uchida, T.*

A dual inhibitor against prolyl isomerase Pin1 and cyclophilin discovered by a novel real-time fluorescence detection method.[

Biochem. Biophys. Res. Commun., 406(3), 439-443 (2011).

 

Publications 2010-1997

Kato T, Hori M, Ogawa T, Muramoto K, Toriyama K (2010)

Expression of gene for Discorea batatas tuber lectin transgenic tobacco confers resistance to green-peach aphid.
Plant Biotechnology 27, 141-145.

 

Shiozaki K, Shiozaki M, Masuda J, Yamauchi A, Ohwada S, Nakano T, Yamaguchi T, Saito T, Muramoto K, Sato M (2010)
 Identification of oyster-derived hypotensive peptide acting as angiotensin-I-converting enzyme inhibitor.
Fisheries Science 76(5): 865-872

 

Konno A, Yonemaru S, Kitagawa A, Muramoto K, Shirai T,  and Ogawa T (2010)
Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants.    
BMC Evolutionary Biology, 10:43doi:10.1186/1471-2148-10-43.

 

Konno A, Ogawa T, Shirai T (2010)
ANCESTRAL PROTEIN RECONSTRUCTION AS A NEW FIELD IN PROTEIN ENGINEERING

In: Ribosomal Proteins and Protein Engineering: ISBN: 978-1-60741-005-8 (Ed.Valter Ortendhal and Hjalmar Salchow) 2010 Nova Science Publishers, Inc.

Y. Watanabe, M. Abolhassani, Y. Tojo, Y. Suda, K. Miyazawa, Y. Igarashi, K. Sakuma, T. Ogawa, K. Muramoto
Evaluation of silica gel-immobilized phosphorylcholine columns for size exclusion chromatography and their application in the analysis of the subunit structures of fish-egg lectins.
J. Chromatography A, 1216 (48), 8563-8566 (2009).

 

A. Konno, Y. Suzuki, T. Ogawa, T. Taniuchi

UV irradiation promotes the accumulation of triglyceride in Lipomyces lipofer.
Biosci. Biotech. Biochem., 73 (11), 2474-2477 (2009).

 

Shirai, T., Watanabe, Y., Lee, M.-s., Ogawa, T., Muramoto, K.
Structure of Rhamnose-binding Lectin CSL3: Unique Pseudo-tetrameric Architecture of a Pattern Recognition Protein.
J. Mol. Biol., 391 (2), 390-403 (2009). (nominated by PubAdvanced)

 

Y. Ohizumi, M. Gaidamashvili, S. Ohwada, K. Matsuda, J. Kominami, S. Nakamura-Tsuruta, J. Hirabayashi, T. Naganuma, T. Ogawa, K. Muramoto
Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae).
J.Agric.Food Chem., 57 (7), 2896-2902 (2009).

 

Y. Watanabe, H. Tateno, S. Nakamura-Tsuruta, J. Kominami, J. Hirabayashi, O. Nakamura, T. Watanabe, H. Kamiya, T. Naganuma, T. Ogawa, R. J. Naud・ K. Muramoto
The function of rhamnose-binding lectin in innate immunity by restricted binding to Gb3.
Dev. Comp. Immunol., 33, 187-197 (2009).

 

A.P. Adebiyi, A. O. Adebiyi, J. Yamashita, T. Ogawa, and K. Muramoto
Purification and characterization of antioxidative peptides derived from rice bran protein hydrolysates.
Eur. Food Res. Technol., 228, 553-563 (2009).

 

A. P. Adebiyi, A. O. Adebiyi, Y. Hasegawa,T. Ogawa, K. Muramoto
Isolation and characterization of protein fractions from deoiled rice bran.
Eur. Food Res. Technol., 228, 391-401 (2009).

 

小川智久
ベノミクス:毒生物ゲノムプロジェクト.
BIOClinica, 24 (6), 65-71 (2009).

 

S. Yamamoto, T. Naganuma, T. Ogawa, and K. Muramoto
Proteomic analysis of Caco-2 cells treated with food lectins.
J. Clin. Biochem. Nutr., 43 Suppl. 1, 70-73 (2008).

 

M. Seto, T. Ogawa, K. Kodama, K. Muramoto, Y. Kanayama, Y. Sakai, T. Chijiwa and M. Ohno
A novel recombinant system for functional expression of myonecrotic snake phospholipase A2 in escherichia coli using a new fusion affinity tag.
Protein Exp. Purif., 58 (2), 194-202 (2008).

 

H. Matsubara, T. Hayashi, T. Ogawa, K. Muramoto, M. Jimbo, and H. Kamiya
Modulating effect of acorn barnacle C-type lectins on the crystallization of calcium carbonate.
Fish. Sci., 74, 418-424 (2008).

 

Y. Watanabe, N. Shiina, F. Shinozaki, H. Yokoyama, J. Kominami, S. Nakamura-Tsuruta, J. Hirabayashi, K. Sugahara, H. Kamiya, H. Matsubara, T. Ogawa, K. Muramoto
Isolation and characterization of L-rhamnose-binding lectin, which binds to microsporidian, Glugea plecoglossi, from ayu (Plecoglossus altivelis) eggs.
Dev. Comp. Immunol. 32, 487-499 (2008).

 

A. P. Adebiyi, A. O. Adebiyi, D.-H. Jin, T. Ogawa, and K. Muramoto
Rice bran protein-based edible films.
Int. J. Food Sci. Technol., 43(3), 476-483 (2008).

 

A. P. Adebiyi, A. O. Adebiyi, T. Ogawa, and K. Muramoto
Purification and characterization of antioxidative peptides from unfractionated rice bran protein hydrolysates.
Int. J. Food Sci. Technol., 43, 35-43 (2008).

 

Y. Koshi, E. Nakata, M. Miyagawa, S.Tsukiji, T. Ogawa, I. Hamachi
Target-Specific Chemical Acylation of Lectins by Ligand-Tethered DMAP Catalysts
J. Am. Chem. Soc. 130 (1), 245-251 (2008).

 

Y. Watanabe, Y.-H. Chang, T. Naganuma, T. Ogawa, and K. Muramoto
Structure and activities of rhamnose-binding lectins from fish eggs.
Proceeding of the 5th World Fisheries Congress. October 20-24, 2008, Yokohama, Japan. 3g-0676-067.

A. P. Adebiyi, A. O. Adebiyi, T. Ogawa, and K. Muramoto
Preparation and characterization of high quality rice bran proteins.
J. Sci. Food Agric., 87, 1219-1227 (2007).

 

A. Konno, T. Ogawa, T. Shirai, and K. Muramoto
Reconstruction of a probable ancestral form of conger eel galectins revealed their rapid adaptive evolution process for specific carbohydrate recognition.
Mol. Biol. Evol., 24 (11), 2504-2514 (2007).

 

T. Terada, Y. Watanabe, H. Tateno, T. Naganuma, T. Ogawa, K. Muramoto, H. Kamiya
Structural characterization of a rhamnose-binding glycoprotein (lectin) from Spanish mackerel (Scomberomorous niphonius) eggs.
Biochimica et Biophysica Acta, 1770(4), 617-629 (2007).

 

Matsubara, H., Nakamura-Tsuruta, S., Hirabayashi, J., Jimbo, M., Kamiya, H., Ogawa, T., Muramoto, K.
Diverse Sugar-Binding Specificities of Marine Invertebrate C-Type Lectins.
Biosci. Biotech. Biochem., 71 (2), 513-519 (2007).

 

小川智久,村本光二
2章レクチンの精製法(分担執筆) ”生物化学実験法 52 レクチン研究法(山崎信行,八木史郎,小田達也,畠山智充,小川智久編著) 学会出版センター,25-55, 2007.

Ogawa, T.
Molecular diversity of proteins in biological offense and defense systems.
Mol. Div., 10(4), 511-514 (2006).

 

Shirai, T., Shionyu-Mitsuyama, C., Ogawa, T., Muramoto, K.
Structure based studies of the adaptive diversification process of congerins.
Mol. Div., 10(4), 567-573 (2006).

 

Naganuma, T., Ogawa, T., Hirabayashi, J., Kasai, K., Kamiya, H., Muramoto, K.
Isolation, characterization and molecular evolution of a novel pearl shell lectin from a marine bivalve, Pteria penguin.
Mol. Div., 10(4), 607-618 (2006).

 

Chijiwa T., Tokunaga E., Ikeda R., Terada K., Ogawa T., Oda-Ueda N., Hattori S., Nozaki M., Ohno M.
Discovery of novel [Arg(49)]phospholipase A(2) isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A(2) isozymes in the southwestern islands of Japan and Taiwan.
Toxicon, 48(6), 672-682 (2006).

 

Y. Ohno, T. Naganuma, T. Ogawa, and K. Muramoto
Effect of lectins on the transport of food factors in Caco-2 cell monolayers.
J. Agric. Food Chem., 54, 548-553 (2006).

 

O. Nakamura, H. Matsuoka, T. Ogawa, K. Muramto, H. Kamiya, and T. Watanabe
Opsonic effect of congerins, a mucosal galectin of Japanese conger, Conger myriaster (Brevoort).
Fish Shellfish Immunol., 20(3), 433-435 (2006).

 

Matsubara, H., Ogawa, T., Muramoto, K.
Structures and Functions of C-type Lectins in marine Invertebrates.
Tohoku Journal of Agricultural Resarch, 57(1-2), 71-86 (2006).

 

Konno, A., Ogawa, T., Muramoto, K., Shirai, T.
Reconstraction of Ancestral Conger Eel Galectins Have Revealed Their Molecular Diversification Process by Accelerated Evolution.
Peptide Science 2006,138-139 (2006).

 

村本光二,松原裕樹,小川智久,神谷久男
生理活性物質の資源としての利用.
”フジツボ類の最新学”,日本付着生物学会編,恒星社厚生閣,317-334,2006.

 

小川智久, 今野歩, 村本光二, 白井剛
加速進化によるタンパク質の耐熱化:進化工学による耐熱化機構の解明から.
生物物理, 46(4), 201-208 (2006)

村本光二,小川智久,神谷久男
動物レクチン ”海洋生物成分の利用-マリンバイオのフロンティア-”,伏谷伸宏編,シーエムシー出版,276-289,2005

 

A. Uehara, K. Muramoto, T. Imamura, K. Nakayama, J. Potempa, J. Travis, S. Sugawara, and H. Takada
Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter facter) through protease-activated receptors in human gingival fibroblasts in culture.
J. Immunol., 175, 6076-6084 (2005).

 

Matsubara, H., Kabuto, S., Nakahara, N., Ogawa, T., Muramoto, K., Jimbo, M. and Kamiya, H.
Structure and possible function of N-glycans of an invertebrate C-type lectin from the acorn barnacle Megabalanus rosa.
Fish. Sci., 71, 931-940 (2005).

 

Shionyu-Mitsuyama C, Ito Y, Konno A, Miwa Y, Ogawa T, Muramoto K, Shirai T.
In vitro evolutionary thermostabilization of congerin II: a limited reproduction of natural protein evolution by artificial selection pressure.
J. Mol. Biol., 347(2), 385-397(2005).

 

Adebiyi, A. P., Jin, D.-H., Ogawa, T. and Muramoto, K.
Acid Hydrolysis of Protein in a Microcapillary Tube for the Recovery of Tryptophane.
Biosci. Biotech. Biochem., 69(1), 255-257(2005).

 

Ogawa, T. , Chijiwa, T., Oda-Ueda, N. and Ohno, M.
Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom.
Toxicon, 45, 1-14(2005).

Ohno, Y., Naganuma, T., Ogawa, T. and Muramoto, K.
Effect of lectins on the transport of food ingredients in Caco-2 cell cultures.
BioFactors, 21(1-4), 399-401 (2004).

 

Kimura, T., Nakano, T., Yamaguchi, T., Sato, M., Ogawa, T., Muramoto, K., Yokoyama, T., Kan-no, N., Nagahisa, E., Janssen, F. and Grieshaber, M.K.
Complementary DNA Cloning and Molecular Evolution of Opine Dehydrogenases in Some Marine Invertebrates
Marine Biotechnology, 6(5), 493-502 (2004).

 

Yoshimi, K., Shoji, M., Ogawa, T., Yamauchi, A., Naganuma, T., Muramoto, K. and Hanada, S.
Microstructure and Orientation Distribution of Aragonite Crystals in Nacreous Layer of Pearl Shells
Materials Transactions, 45 (04), 999-1004 (2004)

 

Yamane, T., Niwa, M., Miyabe, Y., Shionyu-Mitsuyama, C., Kondo, K., Suzuki, A., Ogawa, T., Muramoto, K., Nakamura, H., Sato, M., Yoshizaki, I., Yamanaka, A. and Ataka, M.
Refinement of Crystallization Condisions for the Crystal Growth Experiment of Animal Lectin (Congerin) in Space and the Evaluation of Grown Crystals.
J. Jpn. Soc. Microgravity Appl., 21, 52-62(2004) .

 

Ogawa, T., Shirai, T., Shionyu-Mitsuyama, C., Yamane, T., Kamiya, H. and Muramoto, K.
The speciation of conger eel galectins by rapid adaptive evolution.
Glycoconj. J., 19, 451-458 (2004).

 

Gaidamashvili, M., Ohizumi, Y., Iijima, S., Takayama, T., Ogawa, T. and Muramoto, K.
Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities.
J. Biol. Chem., 279 (25), 26028-26035 (2004).

 

Hayashi, M. A., Ligny-Lemaire, C., Wollberg, Z., Wery, M., Galat, A., Ogawa, T., Muller, B. H., Lamthanh, H., Doljansky, Y., Bdolah, A., Stocklin, R., Ducancel, F.
Long-sarafotoxins: characterization of a new family of endothelin-like peptides
Peptides.;25(8):1243-51(2004).

 

Ohno, M., Chijiwa, T., Oda-Ueda, N., Ogawa, T., and Hattori, S.
Molecular evolution of myotoxic phospholipase A2 from snake venom.
Toxicon, 42, 841-854 (2004).

 Saito, K., Jin, D.H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T. and Nokihara, K.
Antioxidative properties of tripeptide libraries prepared by the combinatorial chemistry.
Journal of Agricultural and Food Chemistry, 51, 3668-3674 (2003) .

 

Ohno, M., Chijiwa, T., Oda-Ueda, N., Ogawa, T. and Hattori, S.
Molecular evolution of myotoxic phospholipases A(2) from snake venom.
Toxicon, 42, 841-854 (2003).

 

Chijiwa, T., Yamaguchi, Y., Ogawa, T., Deshimaru, M., Nobuhisa, I., Nakashima, K., Oda-Ueda, N., Fukumaki, Y., Hattori, S. and Ohno, M.
Interisland evolution of Trimeresurus flavoviridis venom phospholipase A(2) isozymes.
J. Mol. Evol., 56, 286-293 (2003) .

 

Chijiwa, T., Hamai, S., Tsubouchi, S., Ogawa, T., Deshimaru, M., Oda-Ueda, N., Hattori, S., Kihara, H., Tsunasawa, S. and Ohno, M.
Interisland mutation of a novel phospholipase A(2) from Trimeresurus flavoviridis venom and evolution of crotalinae group II phospholipases A(2).
J. Mol. Evol., 57, 546-554(2003).

 

Ogawa, T., Yonemaru, S., Naganuma, T., Hirabayashi, J., Kasai, K. and Muramoto, K.
Strong Induction of Apoptosis of T Cell Lines by Conger Eel Galectins.
In "Biomolecular Chemistry-A Brige for the Future-" (Ed. by Scientific Program Committee of ISBC 2003), Maruzen Co. Ltd., pp.134-137(2003)

 

Yoshimi, K., Haraguchi, T., Ogawa, T., Kobayashi, T., Sung, M.-S. and Hanada, S.
Nanostructure of Surface Formed by Vacancy Clustering in FeAl.
Mat. Res. Soc. Symp. Proc., 775, P9.49.41-P49.49.46 (2003) .

 

村本光二, 舘野浩章, 小川智久, 神谷久男
海洋動物レクチンの構造と機能の多様性
化学と生物 41, 379-388 (2003).

 

小川智久, 村本光二,神谷久男
レクチンの多様な機能 -生体防御から毒、バイオミネラリゼーションまで-
Boundary, 19, 26-29 (2003).

 

吉見享祐,庄子真由美,山内啓, 小川智久,永沼孝子,村本光二
貝殻の組織を材料学的視点で観察すると,
Boundary, 19, 8-11 (2003).

 

白井剛、塩生-光山クララ、小川智久
メ加速進化による蛋白質機能・構造の変化 魚類ガレクチンを例にしてモ,
蛋白質核酸酵素, 48, 1913 - 1919 (2003).

 

T. Ogawa, T. Shirai, T. Yamane, H. Kamiya, and K. Muramoto
Adaptive evolution of conger eel galectins.
Trends in Glycoscience and Glycotechnology, 14, 177-187 (2002).

 

T. Shirai, Y. Matsui, C. Mitsuyama, T. Yamane, H. Kamiya, T. Ogawa, and K. Muramoto
Crystal structure of a conger eel galectin (congerin II) at 1.45 A resolution: Implication of the accelerated evolution of a new ligand-binding site following gene duplication.
J. Mol. Biol., 321(5), 879-889 (2002).

 

N. Shiina, H. Tateno, T. Ogawa, K. Muramoto, M. Saneyoshi, and H. Kamiya
Isolation and characterization of L-rhamnose-binding lectins from chum salmon (Oncorhynchus keta) eggs.
Fisheries Sci., 68, 1352-1366 (2002).

 

H. Tateno, Y. Shibata, Y. Nagahama, T. Hirai, M. Saneyoshi, T. Ogawa, K. Muramoto, and H. Kamiya
Tissue-specific expression of rhamnose-binding lectins in the steelhead trout (Oncorhynchus mykiss).
Biosci. Biotechnol. Biochem., 66 (6), 1427-1430 (2002).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya, and M. Saneyoshi
Distribution and molecular evolution of rhamnose-binding lectins in Salmonidae: Isolation and charcterization of two lectins from white-spoted charr (Salvelinus leucomaenis) eggs.
Biosci. Biotechnol. Biochem., 66 (6), 1356-1365 (2002).

 

A. Tani, T. Ogawa, T. Nose, N. N. Nikandrov, M. Deshimaru, T. Chijiwa, C. C-. Chang, Y. Fukumaki, and M. Ohno
Characterization, primary structure and molecular evolution of anticoagulant protein from Agkistrodon actus venom,
Toxicon, 40, 803-813 (2002).

 

H. Tateno, T. Yamaguchi, T. Ogawa, K. Muramoto, T. Watanabe, H. Kamiya, and M. Saneyoshi
Immunohistochemical localization of rhamnose-binding lectins in the steelhead trout (Oncorhynchus mykiss).
Develop. Comp. Immunol., 26 (6), 543-550 (2002).

 

T. Ogawa, C. Ishii, Y. Suda, H. Kamiya, and K. Muramoto
High-level expression and characterization of fully active recombinant conger eel galectins in Eschericia coli.
Biosci. Biotechnol. Biochem., 66 (2), 476-480 (2002).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya and M. Saneyoshi
Rhamnose-binding lectins from steelhead trout (Oncorhynchus mykiss) eggs recognize bacterial lipopolysaccharides and lipoteichoic acid
Biosci. Biotechnol. Biochem., 66 (3), 604-612 (2002).

 

Ohno, M., Ogawa, T., Oda-Ueda, N., Chijiwa, T. and Hattori, S.
Accelerated and regional evolution of snake venome isozyme.
In "Perspectives in Molecular Toxinology" (Ed. by A. Menez), Johon Wiley & Sons, pp. 387-400 (2002).

 

加藤美樹,金東浩,永沼孝子,小川智久,村本光二
分離大豆たん白質からのフィチン酸の酸抽出除去とそれのたん白質特性への影響.
大豆たん白質研究, 5, 41-46 (2002).

 

小川智久
タンパク質の加速進化による構造と機能の多様化.
大阪大学蛋白質研究所 生体分子解析センターだより, 23, 18-22 (2002).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya, T. Hirai and M. Saneyoshi
A novel rhamnose-binding lectin family from eggs of steelhead trout (Oncorhynchus mykiss) with different structures and tissue distribution
Biosci. Biotechnol. Biochem., 65 (6), 1328-1338 (2001).

 

K. Muramoto, D.-H. Jin, Y. Niino, K. Fujiwara, S. Kabuto, T. Ogawa, M. Toda and H. Kamiya
Comparison of the amino acid sequences of acorn barnacle lectins showing different inhibitory activities toward the crystal growth of calcium carbonate
Fisheries Sci., 67, 703-709 (2001).

 

鈴木美葉子,中村朋之,岡井直子,小川智久,村本光二
大豆プロテオリピド-アポタンパク質とオレオシンの分子構造的相関性
大豆たん白質研究,4,27-32 (2001).

 D.-H. Jin, Y. Zhang, Y. Suzuki, T. Naganuma, T. Ogawa, E. Hatakeyama and K. Muramoto
Inhibitory effect of protein hydrolysates on calcium carbonte crystallization
J. Agric. Food Chem., 48 (11), 5450-5454 (2000).

 

S. Kabuto, T. Ogawa, K. Muramoto, V. Oosthuizen and R.J. Naude
The amino acid sequence of pancreatic α-amylase from the ostrich, Struthio camelus
Comp. Biochem. Physiol. B, 127, 481-490 (2000).

 

M. Yamaguchi, T. Ogawa, K. Muramoto, M. Jimbo and H. Kamiya
Effects of culture conditions on the expression level of lectin in Mycrocystis aeruginosa (Freshwater cyanobacterium)
Fisheries Sci., 66, 665-669 (2000).

 

T. Chijiwa, M. Deshimaru, I. Nobuhisa, M. Nakai, T. Ogawa, N. Oda, K. Nakashima, Y. Fukumaki, Y. Shimohigashi, S. Hattori, and M. Ohno
Regional evolution of venom-gland phospholipase A2 isoenzymes of Trimeresurus flavoviridis snakes in the southwestern islands of Japan
Biochem. J., 347, 491-499 (2000).

 

Y. Chuman, I. Nobuhisa, T. Ogawa, M. Deshimaru, T. Chijiwa, N.-H. Tan, Y. Fukumaki, Y. Shimohigashi, F. Ducancel, J.-C. Boulain, A. Menez and M. Ohno
Regional and accelerated molecular evolution in group I snake venom gland phospholipase A2 isozyme
Toxicon, 38 (3), 449-462 (2000).

 

白井 剛, 小川智久
加速進化で生まれた特異構造をもつ新規ガレクチンファミリー 自然選択より出現した“タンパク質の新規フォールド”, 化学と生物, 38 (10), 636-638 (2000).

 

M. Yamaguchi, T. Ogawa, K. Muramoto, Y. Kamio, M. Jimbo and H. Kamiya
Isolation and Characterization of a Mannan-Binding Lectin from the Freshwater Cyanobacterium (Blue-Green Algae) Microcystis viridis
Biochem. Biophys. Res. Commun., 265, 703-708 (1999).

 

S. Higuchi, N. Murayama, K. Saguchi, H. Ohi, Y. Fujita, A. C. Camargo, T. Ogawa, M. Deshimaru, M. Ohno
Bradykinin-potentiating peptides and C-type natriuretic peptides from snake venom
Immunopharmacology, 44(1-2),129-135 (1999).

 

Y. Umezawa, Y. Sato, T. Naganuma, T. Ogawa and K. Muramoto
Stability of Soybean Lectin during Food Processing and in Digestive Tract
Soy Protein Research, Japan, 2, 59-64 (1999).

 

T. Shirai, C. Mitsuyama, Y. Niwa, Y. Matsui, H. Totta, T. Yamane, H. Kamiya, C. Ishii, T. Ogawa and K. Muramoto
High-resolution structure of congerin I in lactose-liganded and ligand-free forms: Emergence of a new structure class by accelerated evolution
Structure, 7, 1223-1233 (1999).

 

T. Ogawa, C. Ishii, D. Kagawa, K. Muramoto and H. Kamiya
Accelerated evolution in the protein-coding region of galectin cDNAs, congerin I and congerin II, from skin mucus of conger eel (Conger myriaster)
Biosci. Biotechnol. Biochem., 63(7), 1203-1208 (1999).

 

K. Muramoto, D. Kagawa, T. Sato, T. Ogawa, Y. Nishida and H. Kamiya
Functional and structural characterization of multiple galectins from the skin mucus of conger eel, Conger myriaster
Comp. Biochem. Physiol. Part B, 123, 33-45 (1999).

 

I. Nobuhisa, S. Inamasu, M. Nakai, A. Tatsui, T. Mimori, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Characterization and evlutionary aspect of a Trimeresurus flavoviridis serum inhibitor, PLI-I, against its venom basic phospholipase A2 isozymes
Peptide Science-Present and Future(Ed, by Y. Shimonishi), p 360-361, Kluwer Academic Publishers, Great Britain (1999).

 

T. Ogawa
Diet and Molecular Evolution -Accelerated Evolution of Snake Venom Isozymes-, In Prospects of Nutrition and Food Science in the 21st Century (Challenges by Young Scientist of the Graduate School ofAgricultural Science, Tohoku University) Nutrition and Food Science Selection 1 (Ed. by N. Yasumoto, H, Ohrui and K. Ohkubo) , p 46-55, NIhon Shokuhin Shuppan, Tokyo (1999).

 

 H. Tateno, A. Saneyoshi, T. Ogawa, K. Muramoto, H. Kamiya and M. Saneyoshi
Isolation and characterization of rhamnose-binding lectins from eggs of steelhead trout (Oncorhynchus mykiss) homologous to low density lipoprotein receptor superfamily
J. Biol. Chem., 273, 19190-19197 (1998).

 

N. Okai, M. Fukasaku, J. Kaneko, T. Tomita, K. Muramoto and Y. Kamio
Molecular properties and activity of carboxyl-terminal truncated form of xylanase 3 from Aeromonas caviae W-61
Biosci. Biotechnol. Biochem., 62(8), 1560-1567 (1998).

 

M. Toda, M. Jimbo, K. Muramoto, R. Sakai and H. Kamiya
Isolationand characterization of a D-galactose binding lectin from the acorn barnacle Balanus rostratus
Fish. Sci., 64(4), 638-642 (1998).

 

H.-S. Seo, Y. Endo, K. Muramoto, K. Fujimoto, M. Moku and K. Kawaguchi
Amino acid composition of proteins in myctophid fishes in the subarctic and tropical Pacific Ocean
Fish. Sci., 64(4), 652-653 (1998).

 

M. Yamaguchi, M. Jimbo, R. Sakai, K. Muramoto and H. Kamiya
Purification and characterization of Microcystis aeruginosa (freshwater cyanobacterium) lectin
Comp. Biochem. Physiol. 119B, 593-597 (1998).

 

H. -M. Chen, K. Muramoto, F. Yamauchi, K. Fujimoto and K. Nokihara
Antioxidative properties of histidine-containing peptides designed from peptide fragments found in the digests of a soybean protein
J. Agric. Food Chem., 46, 49-53 (1998).

 

S. Kabuto and K. Muramoto
Simple method for detecting glycoproteins dot-blotted or electro-blotted on to a polyvinylidene difluoride membrane
Biosci. Biotech. Biochem., 62(1), 188-189 (1998).

 

V. Oosthuizen, R. J. Naude, W. Oelofsen, K. Muramoto and H. Kamiya
Ostrich intestinal glycohydrolases: Distribution, purification and partial characterization
Int. J. Biochem. Cell Biol., 30(3), 339-352 (1998).

 

M. Ohno, R. Menez, T. Ogawa, J. M. Danse, Y. Shimohigashi, C. Fromen, F. Ducancel, S. Zinn-Justin, M. H. Le Du, J.-C.Boulain, T. Tamiya, and A. Menez
Molecular Evolution of Snake Toxins: Is theFunctional Diversity of Snake Toxins Associated with a Mechanism of Accelerated Evolution?
Prog. in Nucl. Acid Res. and Mol. Biol., 39, 307-364 (1998).

 

I. Nobuhisa, T. Ogawa, M. Deshimaru, T. Chijiwa, K. Nakashima, Y. Chuman, Y. Shimohigashi, Y. Fukumaki, S. Hattori, and M. Ohno
Retrotransposable CR1-like elements in crotalinae snake genomes
Toxicon, 36(6), 915-920 (1998).

 

金東浩,鈴木泰子,永沼孝子,小川智久,村本光二
大豆たん白質からのカルシウム吸収促進ペプチドの作出
大豆たん白質研究,1,63-68(1998).

 

C. L. Frost, R. J. Naude, W. Oelofsen and K. Muramoto
Ostrich α-antichymotrypsin: Purification and partial characterization of the serum inhibitor
Int. J. Biochem. Cell Biol., 29(4), 595-603 (1997).

 

S. Klinkradt, R. J. Naude, K. Muramoto and W. Oelofsen
Purification and characterization of proteasome from Ostrich liver
Int. J. Biochem. Cell Biol., 29(4), 611-622 (1997).

 

J. Kaneko, K. Muramoto and Y. Kamio
Gene of LukF-PV-like component of Panton-Valentine leukocidin in Staphylococcus aureus P83 is linked with lukM
Biosci. Biotech. Biochem., 61(3), 541-544 (1997).

 

K. Nokihara, T. Yasuhara, K. Muramoto, E. Ando and V. Wray
Studies on peptides exhibiting antioxidative activity: Construction of a peptide library and screening
Petide Chemistry 1996 (Ed. by C. Kitada), p. 245-248, Protein Research Foundation, Osaka (1997).

 

H. -M. Chen, K. Muramoto, F. Yamauchi, H. Ochi and K. Nokihara
Characterization of antioxidative peptides from soybean proteins
In Proceedings of International Conference on Food Factors- Chemistry and Cancer Prevention-, Springer-Veriag Tokyo Berlin Heidelberg New york London Paris Hong Kong, p639-641 (1997).

 

I. Nobuhisa, S. Inamasu, M. Nakai, A. Tatsui, T. Mimori, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Characterization and evolution of a gene encoding a Trimeresurus flavoviridis serum protein that inhibits basic phospholipase A2 isozymes in the snake's venom
Eur. J. Biochem., 249, 838-845 (1997).

 

I. Nobuhisa, M. Deshimaru, T. Chijiwa, K. Nakashima, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Structures of genes encoding phospholipase A2 inhibitors from the serum of Trimeresurus flavoviridis snake
Gene, 191, 31-37 (1997).

 

T. Ogawa, Y. Shimohigashi and M. Ohno
Evidence for functional involvement of Asparagine 67 in substrate recognition by snake venom phospholipase A2
J. Biochem., 122, 955-960 (1997).

 

P. Garnier, F. Ducancel, T. Ogawa, J.-C. Boulain, F. Goudey-Perriere, C. Perriere, A. Menez
Complete amino-acid sequence of the b-subunit of VTX from venom of the stonefish (Synanceia verrucosa) as identified from cDNA cloning experiments
Biochim. Biophys. Acta, 1337, 1-5 (1997).

 

村本光二,陳華敏,斎藤晃一郎,小川智久
大豆由来抗酸化ペプチドと非ペプチド性抗酸化剤の相乗作用
大豆たん白質研究会会誌,18, 55-61 (1997).

 

小川智久
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東北大学大学院農学研究科農芸化学専攻

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