東北大学 大学院生命科学研究科

 生 命 素 子 機 能 分 野 Laboratory of Functional Biomolecules
発表論文

Publications 2016

Takashi YAMAZAKI, Tomohisa OGAWA, Koji MURAMOTO, Jun NAKAHIGASHI, Atsuko TAKEUCHI and Hiroshi UEDA: Isolation and Biochemical Characterization of Mucus Proteins of Japanese Bunching Onion (Allium fistulosum) Green Leaves. Food Sci. Technol. Res., in press.

 

Publications 2015

Eri Kenmochi, Syed Rashel Kabir, Tomohisa Ogawa, Ryno Naude, Hiroaki Tateno, Jun Hirabayashi and *Koji Muramoto “Isolation and Biochemical Characterization of Apios Tuber Lectin” Molecules, 20 (1), 987-1002 (2015).

 

Yumi OHASHI, Ryo ONUMA, Takako NAGANUMA, Tomohisa OGAWA, Ryno NAUDE, Kiyoshi NOKIHARA and Koji MURAMOTO: Antioxidant Properties of Tripeptides Revealed by a Comparison of Six Different Assays. Food Sci. Technol. Res., 21, 695-704 (2015).

 

Ryo Nemoto, Shintaro Yamamoto, Tomohisa Ogawa, Ryno Naude and Koji Muramoto: Effect of Chum Salmon Egg Lectin on Tight Junctions in Caco-2 Cell Monolayers. Molecules 2015, 20, 8094-8106; doi:10.3390/molecules20058094

 

Nalise Low Ah Kee, Jason Krause, Gregory L. Blatch, Koji Muramoto, Kazuo Sakka, Makiko Sakka, Ryno J. Naudé, Leona Wagner, Raik Wolf, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth, Wojciech P. Mielicki, Carminita L. Frost: The proteolytic profile of human cancer procoagulant suggests that it promotes cancer metastasis at the level of activation rather than degradation. Protein J., 34,338-348 (2015).

 

G.H.M. Sagor, T. Berberich, S. Tanaka, M. Nishiyama, Y. Kanayama, S. Kojima, K. Muramoto, and T. Kusano: A novel strategy to produce sweeter tomato fruits with high sugar contents by fruit-specific expression of a single bZIP transcription factor gene. Plant Biotechnology Journal, DOI: 10.1111/pbi.12480 (2015).

 

村本光二: 抗酸化ペプチド, “化粧品素材としてのアミノ酸・ペプチド最前線”,監修:坂本一民,シーエムシー・リサーチ,311-321,2015.

 

小川智久 ”マベ真珠バイオミネラリゼーション:マトリックスタンパク質による結晶界面制御” Colloid and Interface Communication (C & I Commun), 40 (1), 27-30 (2015).

 

Publications 2014

Naganuma, T., Hoshino, W., Shikanai, Y., Sato, R., Liu, K., Sato, S., Muramoto, K., Osada, M., Yoshimi, K., Ogawa, T.* (2014) Novel Matrix Proteins of Pteria penguin Pearl Oyster Shell Nacre Homologous to the Jacalin-Related β-Prism Fold Lectins. PLoS ONE 9(11): e112326. doi:10.1371/journal.pone.0112326. (featured in Nature Chemical Biology’s News & Views, January Issue 2015)

 

Odei-Addo, F., Frost, C., Smith, N., Ogawa, T., Muramoto, K., Oliva, MLV,  Gráf, L., Naude, R.* (2014) Biochemical characterization of Acacia schweinfurthii serine proteinase inhibitor. J. Enzyme Inh. Med. Chem. 29, 633-638.

 

Ogawa, T.* and Shirai, T. (2014) Chapter 44:  Tracing Ancestral Specificity of Lectins: Ancestral Sequence Reconstruction Method as a New Approach in Protein Engineering. In: Lectins Methods and Protocols Part4, Method in Molecular Biology, (Ed. by Hirabayashi, J.) p.p. 539-551, Humana Press ISSN: 1064-3745, 1200:539-51. DOI: 10.1007/978-1-4939-1292-6_44

 

Tamai, Keiichi; Nakamura, Mao; Mizuma, Masamichi; Mochizuki, Mai; Yokoyama, Misa; Endo, Hiroyuki; Yamaguchi, Kazunori; Nakagawa, Takayuki; Shiina, Masaaki; Unno, Michiaki; Muramoto, Koji; Sato, Ikuro; Satoh, Kennichi; Sugamura, Kazuo; Tanaka, Nobuyuki: Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinoma. Cancer Science, DOI: 10.1111/cas.12406 105, 667-674 (2014).

 

村本光二: 大豆の各種成分の機能性, “大豆の栄養と機能性”,シーエムシー出版,12-19,2014.

 

Publications 2013

Yamamoto, S., Tomiyama, M., Nemoto, R., Naganuma, T., Ogawa, T., Muramoto, K. (2013) Effects of Food Lectins on the Transport System of Human Intestinal Caco-2 Cell Monolayers. Biosci. Biotech. Biochem., 77 (9) 1917-1924.

 

Watanabe, Y., Chang, Y.-H. Nakamura, O., Naganuma, T., Ogawa, T., Muramoto, K. (2013) Rhamnose-binding lectins induce respiratory burst activity in macrophage cells from rainbow trout. Fisheries Sci., 10.1007/s12562-013-0624-7.

 

Ogawa, T.* and Shirai, T. (2013) Experimental molecular archeology: reconstruction of ancestral mutants and evolutionary history of proteins as a new approach in protein engineering.  In: Protein Engineering -Technology and Application (Ed. by T. Ogawa) InTech, ISBN 980-953-307-520-9

 

Y. Watanabe, T. Naganuma, T. Ogawa, and K. Muramoto (2013) Chapter 4: Lectins of marine origin and their clinical applications.  In: Antitumor potential and other emerging medicinal properties of natural compounds (Ed. by E.F. Fang and T.B. Ng) Springer, ISBN 978-94-007-6213-8.DOI 10.1007/978-94-007-6214-5.

 

Hiroki Shibata · Mayumi Yamamoto · Nana Tuckett · Tomohisa Ogawa · Kazuki Mori · Takahito Chijiwa · Shosaku Hattori · Naoko Oda-Ueda · Satoru Kuhara · Motonori Ohno · Yasuyuki Fukumaki.  Whole genome sequencing of Asian pit viper, Habu, Protobothrops flavoviridis and its repetitive landscape.  GENES & GENETIC SYSTEMS 88(6):370-370 · DECEMBER 2013

 

村本光二:抗酸化活性の測定法. 細胞,45,642-645 (2013).

 

Publications 2012

Yoshimura S, Komatsu M, Kaku K, Hori M, Ogawa T, Muramoto K, Kazama T, Ito Y, Toriyama K. (2012) Production of transgenic rice plants expressing Dioscprea batatus tuber lectin 1 to confer resistance against brown plant hopper. Plant Biotechnol. 29: 501-504.

 

Mizuki Watanabe, Osamu Nakamura, Koji Muramoto, and Tomohisa Ogawa (2012)

Allosteric regulation of the carbohydrate-binding ability of a novel conger Eel galectin by D-mannoside

J. Biol. Chem.  287 (37) 31061-31072.

 

Nakamura O., Watanabe M., Ogawa T., Muramoto K., Ogawa K., Tsutsui S., and Kamiya H (2012)

Galectins in the abdominal cavity of conger eel, Conger myriaster, participate in the cellular encapsulation of parasitic nematode by host cells Fish and Shellfish Immunology 33, 780-787.

 

Bhangoo, S., Copits, B., Nakamura, Y., Frausto S., Robbins J., Gill M.B., Smith, C., Ogawa, T., Muramoto K., Sakai, R. and Swanson, G.T.* (2012) Modulation of AMPA and kainate receptors by galectins. The FASEB Journal. 26:10482.

 

村本光二:三次機能,“大豆の機能と科学”,小野伴忠,下山田真,村本光二(編),朝倉書店,72-99,2012.

 

村本光二: 抗酸化ペプチド, “機能性アミノ酸・ペプチドの技術と市場”,シーエムシー出版,90-101,2012.

 

 Publications 2011

Yamashita J., Chen H.-M., Naganuma T., Ogawa T., and Muramoto K. (2011)

Changes of functional components and antioxidative activity in the process of fermentation of soybeans.

ACS Symposium Series. 1059  In Chemistry, Texture, and Flavor of Soy; Ed by Cadwallader, K. et al; Chapter 10:  p155-169.

 

Krause J., Tshidino S. C., Ogawa T., Watanabe Y., Oosthuizen V., Somai B., Muramoto K., Naudé R. J.  (2011)

Purification and partial characterization of ostrich skeletal muscle cathepsin D and its activity during meat maturation. Meat Science 87: 196-201.

 

Konno A, Kitagawa A, Watanabe M, Ogawa T, Shirai T (2011)

Tracing protein evolution through ancestral structures of fish galectin.
Structure 19 (5): 711-721. (nominated by the Faculty of 1000)

 

Ogawa T, Watanabe M, Naganuma T and Muramoto K (2011)
Diversified carbohydrate-binding lectins from marine resources.
Journal of Amino Acids, 2011: Article ID 838914, 20 pages doi:10.4061/2011/838914

 

村本光二(2011)生体分子間相互作用,“分析化学便覧”,日本分析化学会編,丸善出版,659-662

 

 

 Publications 2010

Kato T, Hori M, Ogawa T, Muramoto K, Toriyama K (2010)

Expression of gene for Discorea batatas tuber lectin transgenic tobacco confers resistance to green-peach aphid.
Plant Biotechnology 27, 141-145.

 

Shiozaki K, Shiozaki M, Masuda J, Yamauchi A, Ohwada S, Nakano T, Yamaguchi T, Saito T, Muramoto K, Sato M (2010)
 Identification of oyster-derived hypotensive peptide acting as angiotensin-I-converting enzyme inhibitor.
Fisheries Science 76(5): 865-872

 

 Konno A, Yonemaru S, Kitagawa A, Muramoto K, Shirai T,  and Ogawa T (2010)
Protein engineering of conger eel galectins by tracing of molecular evolution using probable ancestral mutants.    
BMC Evolutionary Biology, 10:43doi:10.1186/1471-2148-10-43.

 

 Konno A, Ogawa T, Shirai T (2010)
ANCESTRAL PROTEIN RECONSTRUCTION AS A NEW FIELD IN PROTEIN ENGINEERING

In: Ribosomal Proteins and Protein Engineering: ISBN: 978-1-60741-005-8 (Ed.Valter Ortendhal and Hjalmar Salchow) 2010 Nova Science Publishers, Inc.


Publications 2009

Y. Watanabe, M. Abolhassani, Y. Tojo, Y. Suda, K. Miyazawa, Y. Igarashi, K. Sakuma, T. Ogawa, K. Muramoto
Evaluation of silica gel-immobilized phosphorylcholine columns for size exclusion chromatography and their application in the analysis of the subunit structures of fish-egg lectins.
J. Chromatography A, 1216 (48), 8563-8566 (2009).

 

A. Konno, Y. Suzuki, T. Ogawa, T. Taniuchi

UV irradiation promotes the accumulation of triglyceride in Lipomyces lipofer.
Biosci. Biotech. Biochem., 73 (11), 2474-2477 (2009).

 

S. C. Tshidino, J. Krause, A. P. Adebiyi, K. Muramoto, R. J. Naud・
Purification and partial characterization of a myofibril-bound serine protease from ostrich skeletal muscle.
Comp. Biochem. Phys. - B Biochem. and Mol. Biol., 154 (2), 229-234 (2009).

 

Shirai, T., Watanabe, Y., Lee, M.-s., Ogawa, T., Muramoto, K.
Structure of Rhamnose-binding Lectin CSL3: Unique Pseudo-tetrameric Architecture of a Pattern Recognition Protein.
J. Mol. Biol., 391 (2), 390-403 (2009). (nominated by PubAdvanced)

 

Y. Ohizumi, M. Gaidamashvili, S. Ohwada, K. Matsuda, J. Kominami, S. Nakamura-Tsuruta, J. Hirabayashi, T. Naganuma, T. Ogawa, K. Muramoto
Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae).
J.Agric.Food Chem., 57 (7), 2896-2902 (2009).

 

Y. Watanabe, H. Tateno, S. Nakamura-Tsuruta, J. Kominami, J. Hirabayashi, O. Nakamura, T. Watanabe, H. Kamiya, T. Naganuma, T. Ogawa, R. J. Naud・ K. Muramoto
The function of rhamnose-binding lectin in innate immunity by restricted binding to Gb3.
Dev. Comp. Immunol., 33, 187-197 (2009).

 

A.P. Adebiyi, A. O. Adebiyi, J. Yamashita, T. Ogawa, and K. Muramoto
Purification and characterization of antioxidative peptides derived from rice bran protein hydrolysates.
Eur. Food Res. Technol., 228, 553-563 (2009).

 

A. P. Adebiyi, A. O. Adebiyi, Y. Hasegawa,T. Ogawa, K. Muramoto
Isolation and characterization of protein fractions from deoiled rice bran.
Eur. Food Res. Technol., 228, 391-401 (2009).

 

小川智久
ベノミクス:毒生物ゲノムプロジェクト.
BIOClinica, 24 (6), 65-71 (2009).

 

 村本光二,陳華敏: 抗酸化ペプチド, “機能性ペプチドの最新応用技術-食品・化粧品・ペットフードへの展開”,有原圭三,シーエムシー出版,69-77,2009.

 

 Publications 2008

S. Yamamoto, T. Naganuma, T. Ogawa, and K. Muramoto
Proteomic analysis of Caco-2 cells treated with food lectins.
J. Clin. Biochem. Nutr., 43 Suppl. 1, 70-73 (2008).

 

T. Kuroishi, Y. Endo , K. Muramoto , S. Sugawara
Biotin-deficiency up-regulates TNF-a production in murine macrophages.
J. Leukocyte Biol., 83, 912-920 (2008).

 

M. Seto, T. Ogawa, K. Kodama, K. Muramoto, Y. Kanayama, Y. Sakai, T. Chijiwa and M. Ohno
A novel recombinant system for functional expression of myonecrotic snake phospholipase A2 in escherichia coli using a new fusion affinity tag.
Protein Exp. Purif., 58 (2), 194-202 (2008).

 

S. Tsutsui, Y. Yoshino, S. Matsui, O. Nakamura, K. Muramoto, and T. Watanabe

Isolation of epidermal cells and cDNA cloning of TNF decoy receptors 3 of conger eel, Copnger myriaster.
Fish Shellfish Immunol., 24(3), 316-371 (2008).

 

H. Matsubara, T. Hayashi, T. Ogawa, K. Muramoto, M. Jimbo, and H. Kamiya
Modulating effect of acorn barnacle C-type lectins on the crystallization of calcium carbonate.
Fish. Sci., 74, 418-424 (2008).

 

Y. Watanabe, N. Shiina, F. Shinozaki, H. Yokoyama, J. Kominami, S. Nakamura-Tsuruta, J. Hirabayashi, K. Sugahara, H. Kamiya, H. Matsubara, T. Ogawa, K. Muramoto
Isolation and characterization of L-rhamnose-binding lectin, which binds to microsporidian, Glugea plecoglossi, from ayu (Plecoglossus altivelis) eggs.
Dev. Comp. Immunol. 32, 487-499 (2008).

 

A. P. Adebiyi, A. O. Adebiyi, D.-H. Jin, T. Ogawa, and K. Muramoto
Rice bran protein-based edible films.
Int. J. Food Sci. Technol., 43(3), 476-483 (2008).

 

A. P. Adebiyi, A. O. Adebiyi, T. Ogawa, and K. Muramoto
Purification and characterization of antioxidative peptides from unfractionated rice bran protein hydrolysates.
Int. J. Food Sci. Technol., 43, 35-43 (2008).

 

Y. Koshi, E. Nakata, M. Miyagawa, S.Tsukiji, T. Ogawa, I. Hamachi
Target-Specific Chemical Acylation of Lectins by Ligand-Tethered DMAP Catalysts
J. Am. Chem. Soc. 130 (1), 245-251 (2008).

 

Y. Watanabe, Y.-H. Chang, T. Naganuma, T. Ogawa, and K. Muramoto
Structure and activities of rhamnose-binding lectins from fish eggs.
Proceeding of the 5th World Fisheries Congress. October 20-24, 2008, Yokohama, Japan. 3g-0676-067.

 

村本光二
植物タンパク質
“タンパク質の事典”猪飼篤ほか編,朝倉書店,471-473 (2008).

 

Publications 2007

A. P. Adebiyi, A. O. Adebiyi, T. Ogawa, and K. Muramoto
Preparation and characterization of high quality rice bran proteins.
J. Sci. Food Agric., 87, 1219-1227 (2007).

 

A. Konno, T. Ogawa, T. Shirai, and K. Muramoto
Reconstruction of a probable ancestral form of conger eel galectins revealed their rapid adaptive evolution process for specific carbohydrate recognition.
Mol. Biol. Evol., 24 (11), 2504-2514 (2007).

 

S.E. Pambuka, A.P. Adebiyi, K. Muramoto, and R.J. Naude
Purification and partial characterization of a matrix metalloptoteinase from ostrich skeletal muscle, and its activity during meat maturation.
Meat Sci., 76, 481-488 (2007).

 

M. Jimbo, R. Usui, R. Sakai, K. Muramoto, and H. Kamiya
Purification, cloning and characterization of egg lectins from Tribolodon brandti.
Comp. Biochem. Physiol. B, 147, 164-171 (2007).

 

O. Nakamura, Y. Inaga, S. Suzuki, S. Tsutsui, K. Muramoto, H. Kamiya
Possible roles of congerin, a mucosal galectin of Japanese conger eel, in the intestinal lumen.
Fish Shellfish Immunol., 23, 683-692 (2007).

 

T. Terada, Y. Watanabe, H. Tateno, T. Naganuma, T. Ogawa, K. Muramoto, H. Kamiya
Structural characterization of a rhamnose-binding glycoprotein (lectin) from Spanish mackerel (Scomberomorous niphonius) eggs.
Biochimica et Biophysica Acta, 1770(4), 617-629 (2007).

 

Matsubara, H., Nakamura-Tsuruta, S., Hirabayashi, J., Jimbo, M., Kamiya, H., Ogawa, T., Muramoto, K.
Diverse Sugar-Binding Specificities of Marine Invertebrate C-Type Lectins.
Biosci. Biotech. Biochem., 71 (2), 513-519 (2007).

 

小川智久,村本光二
2章レクチンの精製法(分担執筆) ”生物化学実験法 52 レクチン研究法(山崎信行,八木史郎,小田達也,畠山智充,小川智久編著) 学会出版センター,25-55, 2007.

 

 Publications 2006

Ogawa, T.
Molecular diversity of proteins in biological offense and defense systems.
Mol. Div., 10(4), 511-514 (2006).

 

Shirai, T., Shionyu-Mitsuyama, C., Ogawa, T., Muramoto, K.
Structure based studies of the adaptive diversification process of congerins.
Mol. Div., 10(4), 567-573 (2006).

 

Naganuma, T., Ogawa, T., Hirabayashi, J., Kasai, K., Kamiya, H., Muramoto, K.
Isolation, characterization and molecular evolution of a novel pearl shell lectin from a marine bivalve, Pteria penguin.
Mol. Div., 10(4), 607-618 (2006).

 

Chijiwa T., Tokunaga E., Ikeda R., Terada K., Ogawa T., Oda-Ueda N., Hattori S., Nozaki M., Ohno M.
Discovery of novel [Arg(49)]phospholipase A(2) isozymes from Protobothrops elegans venom and regional evolution of Crotalinae snake venom phospholipase A(2) isozymes in the southwestern islands of Japan and Taiwan.
Toxicon, 48(6), 672-682 (2006).

 

Y. Ohno, T. Naganuma, T. Ogawa, and K. Muramoto
Effect of lectins on the transport of food factors in Caco-2 cell monolayers.
J. Agric. Food Chem., 54, 548-553 (2006).

 

V. Oosthuizen, E. A. G. Prinsloo, K. Muramoto, and R. J. Naude In vitro refolding of recombinant human free secretory component using equilibrium gradient dialysis.
Protein Expression and Purification, 47, 179-185 (2006)..

 

O. Nakamura, H. Matsuoka, T. Ogawa, K. Muramto, H. Kamiya, and T. Watanabe
Opsonic effect of congerins, a mucosal galectin of Japanese conger, Conger myriaster (Brevoort).
Fish Shellfish Immunol., 20(3), 433-435 (2006).

 

Matsubara, H., Ogawa, T., Muramoto, K.
Structures and Functions of C-type Lectins in marine Invertebrates.
Tohoku Journal of Agricultural Resarch, 57(1-2), 71-86 (2006).

 

Konno, A., Ogawa, T., Muramoto, K., Shirai, T.
Reconstraction of Ancestral Conger Eel Galectins Have Revealed Their Molecular Diversification Process by Accelerated Evolution.
Peptide Science 2006,138-139 (2006).

 

村本光二,松原裕樹,小川智久,神谷久男
生理活性物質の資源としての利用.
”フジツボ類の最新学”,日本付着生物学会編,恒星社厚生閣,317-334,2006.

 

小川智久, 今野歩, 村本光二, 白井剛
加速進化によるタンパク質の耐熱化:進化工学による耐熱化機構の解明から.
生物物理, 46(4), 201-208 (2006)

 

 Publications 2005

 村本光二
抗酸化ペプチド
食品加工技術25(2), 48-51, 2005.

 

村本光二,小川智久,神谷久男
動物レクチン ”海洋生物成分の利用-マリンバイオのフロンティア-”,伏谷伸宏編,シーエムシー出版,276-289,2005

 

A. Uehara, K. Muramoto, T. Imamura, K. Nakayama, J. Potempa, J. Travis, S. Sugawara, and H. Takada
Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter facter) through protease-activated receptors in human gingival fibroblasts in culture.
J. Immunol., 175, 6076-6084 (2005).

 

•    Matsubara, H., Kabuto, S., Nakahara, N., Ogawa, T., Muramoto, K., Jimbo, M. and Kamiya, H.
Structure and possible function of N-glycans of an invertebrate C-type lectin from the acorn barnacle Megabalanus rosa.
Fish. Sci., 71, 931-940 (2005).

 

Jimbo, M., Koike, K., Sakai, R., Muramoto, K. and Kamiya, H.
Cloning and characterization of a lectin from the octocoral Sinularia lochmodes.
Biochem. Biophys. Res. Commun., 330, 157-162 (2005).

 

Shionyu-Mitsuyama C, Ito Y, Konno A, Miwa Y, Ogawa T, Muramoto K, Shirai T.
In vitro evolutionary thermostabilization of congerin II: a limited reproduction of natural protein evolution by artificial selection pressure.
J. Mol. Biol., 347(2), 385-397(2005).

 

Adebiyi, A. P., Jin, D.-H., Ogawa, T. and Muramoto, K.
Acid Hydrolysis of Protein in a Microcapillary Tube for the Recovery of Tryptophane.
Biosci. Biotech. Biochem., 69(1), 255-257(2005).

 

Ogawa, T. , Chijiwa, T., Oda-Ueda, N. and Ohno, M.
Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom.
Toxicon, 45, 1-14(2005).

 

Publications 2004

Ohno, Y., Naganuma, T., Ogawa, T. and Muramoto, K.
Effect of lectins on the transport of food ingredients in Caco-2 cell cultures.
BioFactors, 21(1-4), 399-401 (2004).

 

K. Koike, M. Jimbo, R. Sakai, M. Kaeriyama, K. Muramoto, T. Ogata, T. Maruyama, and H. Kamiya
Octocoral chemical signalling selects and controls dinoflagellate symbionts.
Biol Bull., 207, 80-86 (2004).

 

Bewley, C. A., Cai, M., Ray, S., Ghirlando, R., Yamaguchi, M. and Muramoto, K.
New carbohydrate specificity and HIV-1 fusion blocking activity of the cyanobacterial protein MVL: NMR, ITC and sedimentation equilibrium studies.
J. Mol. Biol., 339, 901-914 (2004).

 

Kimura, T., Nakano, T., Yamaguchi, T., Sato, M., Ogawa, T., Muramoto, K., Yokoyama, T., Kan-no, N., Nagahisa, E., Janssen, F. and Grieshaber, M.K.
Complementary DNA Cloning and Molecular Evolution of Opine Dehydrogenases in Some Marine Invertebrates
Marine Biotechnology, 6(5), 493-502 (2004).

 

Yoshimi, K., Shoji, M., Ogawa, T., Yamauchi, A., Naganuma, T., Muramoto, K. and Hanada, S.
Microstructure and Orientation Distribution of Aragonite Crystals in Nacreous Layer of Pearl Shells
Materials Transactions, 45 (04), 999-1004 (2004)

 

Yamane, T., Niwa, M., Miyabe, Y., Shionyu-Mitsuyama, C., Kondo, K., Suzuki, A., Ogawa, T., Muramoto, K., Nakamura, H., Sato, M., Yoshizaki, I., Yamanaka, A. and Ataka, M.
Refinement of Crystallization Condisions for the Crystal Growth Experiment of Animal Lectin (Congerin) in Space and the Evaluation of Grown Crystals.
J. Jpn. Soc. Microgravity Appl., 21, 52-62(2004) .

 

Ogawa, T., Shirai, T., Shionyu-Mitsuyama, C., Yamane, T., Kamiya, H. and Muramoto, K.
The speciation of conger eel galectins by rapid adaptive evolution.
Glycoconj. J., 19, 451-458 (2004).

 

Gaidamashvili, M., Ohizumi, Y., Iijima, S., Takayama, T., Ogawa, T. and Muramoto, K.
Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities.
J. Biol. Chem., 279 (25), 26028-26035 (2004).

 

Hayashi, M. A., Ligny-Lemaire, C., Wollberg, Z., Wery, M., Galat, A., Ogawa, T., Muller, B. H., Lamthanh, H., Doljansky, Y., Bdolah, A., Stocklin, R., Ducancel, F.
Long-sarafotoxins: characterization of a new family of endothelin-like peptides
Peptides.;25(8):1243-51(2004).

 

Ohno, M., Chijiwa, T., Oda-Ueda, N., Ogawa, T., and Hattori, S.
Molecular evolution of myotoxic phospholipase A2 from snake venom.
Toxicon, 42, 841-854 (2004).


 Publications 2003

 Saito, K., Jin, D.H., Ogawa, T., Muramoto, K., Hatakeyama, E., Yasuhara, T. and Nokihara, K.
Antioxidative properties of tripeptide libraries prepared by the combinatorial chemistry.
Journal of Agricultural and Food Chemistry, 51, 3668-3674 (2003) .

 

M. Jimbo, F. Nakanishi, R. Sakai, K. Muramoto, and H. Kamiya
Characterization of L-amino acid oxidase and antimicrobial activity of aplysianin a, a sea hare-derived anitumor- antimicrobial protein.
Fish. Sci., 69, 1240-1246 (2003).

 

A. Uehara, K. Muramoto, H. Takada, and S. Sugawara
Neutrophil serine proteinases activate human nonepithelial cells to produce inflammatory cytokines through protease-activated receptor 2.
J. Immunol., 170, 5690-5696 (2003).

 

K. Muramoto and E. Hatakeyama
Structures and properties of antioxidative peptides derived from food protein digests.
Foods & Food Ingredients Journal of Japan, 208(1), 52-58 (2003).

 

J. R. Chen, T. Okada, K. Muramoto, K. Suetsuna, and S.C. Yang
Identification of angiotensin I converting enzyme inhibitory peptides derived from the peptic digest of soybean protein.
J. Food Biochem., 26(6), 543-554 (2003).

 

Ohno, M., Chijiwa, T., Oda-Ueda, N., Ogawa, T. and Hattori, S.
Molecular evolution of myotoxic phospholipases A(2) from snake venom.
Toxicon, 42, 841-854 (2003).

 

Chijiwa, T., Yamaguchi, Y., Ogawa, T., Deshimaru, M., Nobuhisa, I., Nakashima, K., Oda-Ueda, N., Fukumaki, Y., Hattori, S. and Ohno, M.
Interisland evolution of Trimeresurus flavoviridis venom phospholipase A(2) isozymes.
J. Mol. Evol., 56, 286-293 (2003) .

 

Chijiwa, T., Hamai, S., Tsubouchi, S., Ogawa, T., Deshimaru, M., Oda-Ueda, N., Hattori, S., Kihara, H., Tsunasawa, S. and Ohno, M.
Interisland mutation of a novel phospholipase A(2) from Trimeresurus flavoviridis venom and evolution of crotalinae group II phospholipases A(2).
J. Mol. Evol., 57, 546-554(2003).

 

Ogawa, T., Yonemaru, S., Naganuma, T., Hirabayashi, J., Kasai, K. and Muramoto, K.
Strong Induction of Apoptosis of T Cell Lines by Conger Eel Galectins.
In "Biomolecular Chemistry-A Brige for the Future-" (Ed. by Scientific Program Committee of ISBC 2003), Maruzen Co. Ltd., pp.134-137(2003)

 

Yoshimi, K., Haraguchi, T., Ogawa, T., Kobayashi, T., Sung, M.-S. and Hanada, S.
Nanostructure of Surface Formed by Vacancy Clustering in FeAl.
Mat. Res. Soc. Symp. Proc., 775, P9.49.41-P49.49.46 (2003) .

 

Aono N, Naganuma T, Abe Y, Hara K, Sasada H, Sato E, Yoshida H
Successful production of blastocysts following ultrarapid vitrification with step-wise equilibriition of germinal vesicle-stage mouse oocytes.
Journal of Reproducton and Development 49 (6): 501-506 (2003)

 

Yoshida H., Aono N., Araki Y., and Naganuma T.
Delivery of a healthy new-born using vitrified xygotes that developed from in vitro matured oocytes retrieved from a patient with polycystic ovarian Syndrome.
Reproductive Medicine and Biology 2: 87-90(2003)

 

村本光二, 舘野浩章, 小川智久, 神谷久男
海洋動物レクチンの構造と機能の多様性
化学と生物 41, 379-388 (2003).

 

村本光二
蛍光プローブを用いる抗酸化活性測定法,
ぶんせき,6,321-322 (2003).

 

村本光二,畠山英子
抗酸化ストレスを介した食品タンパク質・ペプチドの脳機能調節作用,
感性福祉研究所年報,4,165-171 (2003).

 

畠山英子,山口政人,村本光二,伊藤豪,本橋豊,樋口重和
脳科学を基礎とした大豆たん白質・ペプチドの学習・記憶・情緒への寄与に関する研究,
大豆たん白質研究,6,147-152 (2003).

 

小川智久, 村本光二,神谷久男
レクチンの多様な機能 -生体防御から毒、バイオミネラリゼーションまで-
Boundary, 19, 26-29 (2003).

 

吉見享祐,庄子真由美,山内啓, 小川智久,永沼孝子,村本光二
貝殻の組織を材料学的視点で観察すると,
Boundary, 19, 8-11 (2003).

 

白井剛、塩生-光山クララ、小川智久
メ加速進化による蛋白質機能・構造の変化 魚類ガレクチンを例にしてモ,
蛋白質核酸酵素, 48, 1913 - 1919 (2003).

 

Publications 2002

M. Sato, T. Hosokawa, T. Yamaguchi, T. Nakano, K. Muramoto, T. Kahara, K. Funayama, A. Kobayashi, and T. Nakano
Angiotensin I-converting enzyme inhibitory peptides derived from wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats.
J. Agric. Food Chem., 50 (21), 6245-6252 (2002).

 

M. Jimbo, F. Nakanishi, R. Sakai, K. Muramoto, and H. Kamiya
Expression of the antitumor-antibacterial glycoprotein aplysianin A in E. Coli.
Fisheries Sci., 68(Suppl. II), 1635-1636 (2002).

 

H. Yako, M. Jimbo, R. Sakai, N. Takamatsu, T. Shiba, K. Muramoto, and H. Kamiya
Multifunctional of the acorn barnacle Megabalanus rosa hemolymph lectins.
Fisheries Sci., 68(Suppl. II), 1127-1130 (2002).

 

T. Ogawa, T. Shirai, T. Yamane, H. Kamiya, and K. Muramoto
Adaptive evolution of conger eel galectins.
Trends in Glycoscience and Glycotechnology, 14, 177-187 (2002).

 

T. Shirai, Y. Matsui, C. Mitsuyama, T. Yamane, H. Kamiya, T. Ogawa, and K. Muramoto
Crystal structure of a conger eel galectin (congerin II) at 1.45 A resolution: Implication of the accelerated evolution of a new ligand-binding site following gene duplication.
J. Mol. Biol., 321(5), 879-889 (2002).

 

A. Uehara, S. Sugawara, K. Muramoto, and H. Takada
Activation of human oral epithelial cells by neutrophil proteinase 3 through protease-activated receptor-2.
J. Immunol., 169, 4594-4603 (2002).

 

A.R. Thomas, V. Oosthuizen, R.J. Naude, and K. Muramoto
Purification and characterization of the 20S proteasome from ostrich skeletal muscle.
Biol. Chem., 383, 1267-1270 (2002).

 

N. Shiina, H. Tateno, T. Ogawa, K. Muramoto, M. Saneyoshi, and H. Kamiya
Isolation and characterization of L-rhamnose-binding lectins from chum salmon (Oncorhynchus keta) eggs.
Fisheries Sci., 68, 1352-1366 (2002).

 

H. Tateno, Y. Shibata, Y. Nagahama, T. Hirai, M. Saneyoshi, T. Ogawa, K. Muramoto, and H. Kamiya
Tissue-specific expression of rhamnose-binding lectins in the steelhead trout (Oncorhynchus mykiss).
Biosci. Biotechnol. Biochem., 66 (6), 1427-1430 (2002).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya, and M. Saneyoshi
Distribution and molecular evolution of rhamnose-binding lectins in Salmonidae: Isolation and charcterization of two lectins from white-spoted charr (Salvelinus leucomaenis) eggs.
Biosci. Biotechnol. Biochem., 66 (6), 1356-1365 (2002).

 

A. Tani, T. Ogawa, T. Nose, N. N. Nikandrov, M. Deshimaru, T. Chijiwa, C. C-. Chang, Y. Fukumaki, and M. Ohno
Characterization, primary structure and molecular evolution of anticoagulant protein from Agkistrodon actus venom,
Toxicon, 40, 803-813 (2002).

 

H. Tateno, T. Yamaguchi, T. Ogawa, K. Muramoto, T. Watanabe, H. Kamiya, and M. Saneyoshi
Immunohistochemical localization of rhamnose-binding lectins in the steelhead trout (Oncorhynchus mykiss).
Develop. Comp. Immunol., 26 (6), 543-550 (2002).

 

Z. H. Howlader, S. Kamiyama, H. Shirakawa, Y. Murakami, M. Ito, M. Komai, K. Muramoto, and Y. Furukawa
Detoxification of oxidized LDL by transferring its oxidation products to lecithin: cholesterol acyltransferase.
Biochem. Biophys. Res. Commun., 291, 758-763 (2002).

 

H. Kamiya, M. Jimbo, H. Yako, K. Muramoto, O. Nakamura, R. Kado, and T. Watanabe
Participation of the C-type hemolymph lectin in mineralization of the acorn barnacle Megabalanus rosa.
Marine Biology, 140, 1235-1240 (2002).

 

T. Ogawa, C. Ishii, Y. Suda, H. Kamiya, and K. Muramoto
High-level expression and characterization of fully active recombinant conger eel galectins in Eschericia coli.
Biosci. Biotechnol. Biochem., 66 (2), 476-480 (2002).

 

C.L. Frost, R.J. Naude, and K. Muramoto
Ostrich antithrombin III: Kinetics and mechanism of inhibition of ostrich thrombin.
Int. J. Biochem. Cell Biol., 34 (9), 1164-1171 (2002).

 

N.T. Mkwetshana, R.J. Naude, W. Oelofsen, K. Muramoto, and T. Naganuma
Thepurification and characterization of m-calpain from ostrich brain.
Int. J. Biochem. Cell Biol., 34, 337-347 (2002).

 

N.T. Mkwetshana, R.J. Naude, and K. Muramoto
The purification and characterization of u-calpain and calpastatin from ostrich brain.
Int. J. Biochem. Cell biol., 34, 613-624 (2002).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya and M. Saneyoshi
Rhamnose-binding lectins from steelhead trout (Oncorhynchus mykiss) eggs recognize bacterial lipopolysaccharides and lipoteichoic acid
Biosci. Biotechnol. Biochem., 66 (3), 604-612 (2002).

 

O. Nakamura, M. Saeki, H. Kamiya, K. Muramoto, and T. Watanabe
Development of epidermal and mucosal galectin containing cells in metamorphosing leptocephali of Japanese conger.
J. Fish Biol., 61, 822-833 (2002).

 

Ohno, M., Ogawa, T., Oda-Ueda, N., Chijiwa, T. and Hattori, S.
Accelerated and regional evolution of snake venome isozyme.
In "Perspectives in Molecular Toxinology" (Ed. by A. Menez), Johon Wiley & Sons, pp. 387-400 (2002).

 

加藤美樹,金東浩,永沼孝子,小川智久,村本光二
分離大豆たん白質からのフィチン酸の酸抽出除去とそれのたん白質特性への影響.
大豆たん白質研究, 5, 41-46 (2002).

 

山口政人,村本光二,本橋豊,宮崎良文,畠山英子
生命科学を基礎とする感性と食環境の相関に関する研究-食品タンパク質・ペプチドの摂取による精神活動への影響-
感性福祉研究所年報,3,103-107 (2002).

 

小川智久
タンパク質の加速進化による構造と機能の多様化.
大阪大学蛋白質研究所 生体分子解析センターだより, 23, 18-22 (2002).

 

  Publications 2001

A. R. Thomas, R. J. Naude, W. Oelofsen, T. Naganuma and K. Muramoto
Purification and partial characterisation of 2-antiplasmin and plasmin(ogen)from ostrich plasma
Comp. Biochem. Physiol., 129B, 809-820 (2001).

 

R. Onizuka, H. Kamiya, K. Muramoto, R. Goro, K. Inoue, K. Kumamoto, Y. Nakajima, S. Iida and F. Ishigami
Purification of the major allergen of red soft coral (Dendronephthya nipponica)
Int. Arch. Allergy Immunol., 125, 135-143 (2001).

 

O. Nakamura, T. Watanabe, H. Kamiya and K. Muramoto
Galectin containing cells in the skin and mucosal tissues in Japanese conger eel, Conger myriaster:
An immunohistochemical study, Develop. Comp. Immunol., 25 (5-6), 431-437 (2001).

 

H. Tateno, T. Ogawa, K. Muramoto, H. Kamiya, T. Hirai and M. Saneyoshi
A novel rhamnose-binding lectin family from eggs of steelhead trout (Oncorhynchus mykiss) with different structures and tissue distribution
Biosci. Biotechnol. Biochem., 65 (6), 1328-1338 (2001).

 

K. Muramoto, D.-H. Jin, Y. Niino, K. Fujiwara, S. Kabuto, T. Ogawa, M. Toda and H. Kamiya
Comparison of the amino acid sequences of acorn barnacle lectins showing different inhibitory activities toward the crystal growth of calcium carbonate
Fisheries Sci., 67, 703-709 (2001).

 

鈴木美葉子,中村朋之,岡井直子,小川智久,村本光二
大豆プロテオリピド-アポタンパク質とオレオシンの分子構造的相関性
大豆たん白質研究,4,27-32 (2001).

 

山口政人,村本光二,本橋豊,畠山英子
感性の基盤要素としてのタンパク質およびペプチドの脳機能調節作用
感性福祉研究所年報, 2, 135-141 (2001).

 

   Publications 2000

 D.-H. Jin, Y. Zhang, Y. Suzuki, T. Naganuma, T. Ogawa, E. Hatakeyama and K. Muramoto
Inhibitory effect of protein hydrolysates on calcium carbonte crystallization
J. Agric. Food Chem., 48 (11), 5450-5454 (2000).

 

S. Kabuto, T. Ogawa, K. Muramoto, V. Oosthuizen and R.J. Naude
The amino acid sequence of pancreatic α-amylase from the ostrich, Struthio camelus
Comp. Biochem. Physiol. B, 127, 481-490 (2000).

 

M. Jimbo, M. Yamaguchi, K. Muramoto and H. Kamiya
Cloning of the Microcystis aeruginosa M228 lectin (MAL) gene
Biochem. Biophys. Res. Commun., 273(2), 499-504 (2000).

 

M. Yamaguchi, T. Ogawa, K. Muramoto, M. Jimbo and H. Kamiya
Effects of culture conditions on the expression level of lectin in Mycrocystis aeruginosa (Freshwater cyanobacterium)
Fisheries Sci., 66, 665-669 (2000).

 

K. Muramoto
Physiological functions of plant lectins contained in foodstuffs,
Foods & Food Ingredients Journal of Japan, 187, 11-16 (2000).

 

M. Jimbo, T. Yanohara, K. Koike, K. Koike, R. Sakai, K. Muramoto and H. Kamiya
The D-galactose-binding lectin of the octocoral Sinularia lochmodes: Characterization and possible relationship to the symbiotic dinoflagellates
Comp. Biochem. Physiol. B, 125, 227-236 (2000).

 

T. Chijiwa, M. Deshimaru, I. Nobuhisa, M. Nakai, T. Ogawa, N. Oda, K. Nakashima, Y. Fukumaki, Y. Shimohigashi, S. Hattori, and M. Ohno
Regional evolution of venom-gland phospholipase A2 isoenzymes of Trimeresurus flavoviridis snakes in the southwestern islands of Japan
Biochem. J., 347, 491-499 (2000).

 

Y. Chuman, I. Nobuhisa, T. Ogawa, M. Deshimaru, T. Chijiwa, N.-H. Tan, Y. Fukumaki, Y. Shimohigashi, F. Ducancel, J.-C. Boulain, A. Menez and M. Ohno
Regional and accelerated molecular evolution in group I snake venom gland phospholipase A2 isozyme
Toxicon, 38 (3), 449-462 (2000).

 

村本光二
海洋動物レクチンの分子構造と機能に関する研究
Nippon Suisan Gakkaishi, 66(3), 384-387 (2000).

 

村本光二
食品における脳機能調節因子
感性福祉研究所年報, 1, 118-123 (2000).

 

白井 剛, 小川智久
加速進化で生まれた特異構造をもつ新規ガレクチンファミリー 自然選択より出現した“タンパク質の新規フォールド”, 化学と生物, 38 (10), 636-638 (2000).

 

 

Publications 1999

 L. Wagner, R. J. Naude, W. Oelofsen, T. Naganuma and K. Muramoto
Isolation and partial characterization of dipeptidyl peptidase IV from ostrich kidney, Enzyme & Microbial Technology, 25, 576-583 (1999).

 

M. Yamaguchi, T. Ogawa, K. Muramoto, Y. Kamio, M. Jimbo and H. Kamiya
Isolation and Characterization of a Mannan-Binding Lectin from the Freshwater Cyanobacterium (Blue-Green Algae) Microcystis viridis
Biochem. Biophys. Res. Commun., 265, 703-708 (1999).

 

S. Higuchi, N. Murayama, K. Saguchi, H. Ohi, Y. Fujita, A. C. Camargo, T. Ogawa, M. Deshimaru, M. Ohno
Bradykinin-potentiating peptides and C-type natriuretic peptides from snake venom
Immunopharmacology, 44(1-2),129-135 (1999).

 

Y. Umezawa, Y. Sato, T. Naganuma, T. Ogawa and K. Muramoto
Stability of Soybean Lectin during Food Processing and in Digestive Tract
Soy Protein Research, Japan, 2, 59-64 (1999).

 

T. Shirai, C. Mitsuyama, Y. Niwa, Y. Matsui, H. Totta, T. Yamane, H. Kamiya, C. Ishii, T. Ogawa and K. Muramoto
High-resolution structure of congerin I in lactose-liganded and ligand-free forms: Emergence of a new structure class by accelerated evolution
Structure, 7, 1223-1233 (1999).

 

T. Ogawa, C. Ishii, D. Kagawa, K. Muramoto and H. Kamiya
Accelerated evolution in the protein-coding region of galectin cDNAs, congerin I and congerin II, from skin mucus of conger eel (Conger myriaster)
Biosci. Biotechnol. Biochem., 63(7), 1203-1208 (1999).

 

Y. Takatsuka, M. Onoda, T. Sugiyama, K. Muramoto, T. Tomita and Y. Kamio
Novel characteristics of Selenomonas ruminantium lysine decarboxylase capable of decarboxylating both L-lysine and L-ornithine,
Biosci. Biotechnol. Biochem., 63(6), 1063-1069 (1999).

 

K. Muramoto, D. Kagawa, T. Sato, T. Ogawa, Y. Nishida and H. Kamiya
Functional and structural characterization of multiple galectins from the skin mucus of conger eel, Conger myriaster
Comp. Biochem. Physiol. Part B, 123, 33-45 (1999).

 

N. T. Mkwetshana, R. J. Naude, W. Oelofsen, T. Naganuma and K. Muramoto
The isolation and partial characterization of precursor forms of ostrich carboxypeptidase
Int.J. Biochem. Cell Biol., 31, 331- 343 (1999).

 

I. Nobuhisa, S. Inamasu, M. Nakai, A. Tatsui, T. Mimori, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Characterization and evlutionary aspect of a Trimeresurus flavoviridis serum inhibitor, PLI-I, against its venom basic phospholipase A2 isozymes
Peptide Science-Present and Future(Ed, by Y. Shimonishi), p 360-361, Kluwer Academic Publishers, Great Britain (1999).

 

T. Ogawa
Diet and Molecular Evolution -Accelerated Evolution of Snake Venom Isozymes-, In Prospects of Nutrition and Food Science in the 21st Century (Challenges by Young Scientist of the Graduate School ofAgricultural Science, Tohoku University) Nutrition and Food Science Selection 1 (Ed. by N. Yasumoto, H, Ohrui and K. Ohkubo) , p 46-55, NIhon Shokuhin Shuppan, Tokyo (1999).

 

 

  Publications 1998

 H. Tateno, A. Saneyoshi, T. Ogawa, K. Muramoto, H. Kamiya and M. Saneyoshi
Isolation and characterization of rhamnose-binding lectins from eggs of steelhead trout (Oncorhynchus mykiss) homologous to low density lipoprotein receptor superfamily
J. Biol. Chem., 273, 19190-19197 (1998).

 

N. Okai, M. Fukasaku, J. Kaneko, T. Tomita, K. Muramoto and Y. Kamio
Molecular properties and activity of carboxyl-terminal truncated form of xylanase 3 from Aeromonas caviae W-61
Biosci. Biotechnol. Biochem., 62(8), 1560-1567 (1998).

 

M. Toda, M. Jimbo, K. Muramoto, R. Sakai and H. Kamiya
Isolationand characterization of a D-galactose binding lectin from the acorn barnacle Balanus rostratus
Fish. Sci., 64(4), 638-642 (1998).

 

H.-S. Seo, Y. Endo, K. Muramoto, K. Fujimoto, M. Moku and K. Kawaguchi
Amino acid composition of proteins in myctophid fishes in the subarctic and tropical Pacific Ocean
Fish. Sci., 64(4), 652-653 (1998).

 

M. Yamaguchi, M. Jimbo, R. Sakai, K. Muramoto and H. Kamiya
Purification and characterization of Microcystis aeruginosa (freshwater cyanobacterium) lectin
Comp. Biochem. Physiol. 119B, 593-597 (1998).

 

H. -M. Chen, K. Muramoto, F. Yamauchi, K. Fujimoto and K. Nokihara
Antioxidative properties of histidine-containing peptides designed from peptide fragments found in the digests of a soybean protein
J. Agric. Food Chem., 46, 49-53 (1998).

 

S. Kabuto and K. Muramoto
Simple method for detecting glycoproteins dot-blotted or electro-blotted on to a polyvinylidene difluoride membrane
Biosci. Biotech. Biochem., 62(1), 188-189 (1998).

 

V. Oosthuizen, R. J. Naude, W. Oelofsen, K. Muramoto and H. Kamiya
Ostrich intestinal glycohydrolases: Distribution, purification and partial characterization
Int. J. Biochem. Cell Biol., 30(3), 339-352 (1998).

 

M. Ohno, R. Menez, T. Ogawa, J. M. Danse, Y. Shimohigashi, C. Fromen, F. Ducancel, S. Zinn-Justin, M. H. Le Du, J.-C.Boulain, T. Tamiya, and A. Menez
Molecular Evolution of Snake Toxins: Is theFunctional Diversity of Snake Toxins Associated with a Mechanism of Accelerated Evolution?
Prog. in Nucl. Acid Res. and Mol. Biol., 39, 307-364 (1998).

 

I. Nobuhisa, T. Ogawa, M. Deshimaru, T. Chijiwa, K. Nakashima, Y. Chuman, Y. Shimohigashi, Y. Fukumaki, S. Hattori, and M. Ohno
Retrotransposable CR1-like elements in crotalinae snake genomes
Toxicon, 36(6), 915-920 (1998).

 

村本光二,軒原清史抗酸化ペプチド,
“成人病予防食品の開発”二木鋭雄,吉川敏一,大澤俊彦 編集,シーエムシー,p.159-166 (1998).

 

村本光二,陳華敏大豆ペプチドの抗酸化性
ダイズのヘルシーテクノロジー 河村幸雄,大久保一良 編集,光琳,p.147-166 (1998).

 

金東浩,鈴木泰子,永沼孝子,小川智久,村本光二
大豆たん白質からのカルシウム吸収促進ペプチドの作出
大豆たん白質研究,1,63-68(1998).

 

 

 

Publications 1997

C. L. Frost, R. J. Naude, W. Oelofsen and K. Muramoto
Ostrich α-antichymotrypsin: Purification and partial characterization of the serum inhibitor
Int. J. Biochem. Cell Biol., 29(4), 595-603 (1997).

 

S. Klinkradt, R. J. Naude, K. Muramoto and W. Oelofsen
Purification and characterization of proteasome from Ostrich liver
Int. J. Biochem. Cell Biol., 29(4), 611-622 (1997).

 

J. Kaneko, K. Muramoto and Y. Kamio
Gene of LukF-PV-like component of Panton-Valentine leukocidin in Staphylococcus aureus P83 is linked with lukM
Biosci. Biotech. Biochem., 61(3), 541-544 (1997).

 

K. Nokihara, T. Yasuhara, K. Muramoto, E. Ando and V. Wray
Studies on peptides exhibiting antioxidative activity: Construction of a peptide library and screening
Petide Chemistry 1996 (Ed. by C. Kitada), p. 245-248, Protein Research Foundation, Osaka (1997).

 

H. -M. Chen, K. Muramoto, F. Yamauchi, H. Ochi and K. Nokihara
Characterization of antioxidative peptides from soybean proteins
In Proceedings of International Conference on Food Factors- Chemistry and Cancer Prevention-, Springer-Veriag Tokyo Berlin Heidelberg New york London Paris Hong Kong, p639-641 (1997).

 

I. Nobuhisa, S. Inamasu, M. Nakai, A. Tatsui, T. Mimori, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Characterization and evolution of a gene encoding a Trimeresurus flavoviridis serum protein that inhibits basic phospholipase A2 isozymes in the snake's venom
Eur. J. Biochem., 249, 838-845 (1997).

 

I. Nobuhisa, M. Deshimaru, T. Chijiwa, K. Nakashima, T. Ogawa, Y. Shimohigashi, Y. Fukumaki, S. Hattori, H. Kihara and M. Ohno
Structures of genes encoding phospholipase A2 inhibitors from the serum of Trimeresurus flavoviridis snake
Gene, 191, 31-37 (1997).

 

T. Ogawa, Y. Shimohigashi and M. Ohno
Evidence for functional involvement of Asparagine 67 in substrate recognition by snake venom phospholipase A2
J. Biochem., 122, 955-960 (1997).

 

P. Garnier, F. Ducancel, T. Ogawa, J.-C. Boulain, F. Goudey-Perriere, C. Perriere, A. Menez
Complete amino-acid sequence of the b-subunit of VTX from venom of the stonefish (Synanceia verrucosa) as identified from cDNA cloning experiments
Biochim. Biophys. Acta, 1337, 1-5 (1997).

 

村本光二,陳華敏
大豆ペプチドの抗酸化性
食品工業,40(6), 69-69-79 (1997).

 

村本光二,陳華敏,斎藤晃一郎,小川智久
大豆由来抗酸化ペプチドと非ペプチド性抗酸化剤の相乗作用
大豆たん白質研究会会誌,18, 55-61 (1997).

 

小川智久
ヘビ毒腺アイソザイム遺伝子の適応進化 多様な毒タンパク質の獲得に寄与
化学と生物,35(4),261-263 (1997).

 

 

  Publications 1996

 H. -M. Chen, K. Muramoto, F. Yamauchi and K. Nokihara
Antioxidant activity of designed peptides based on the antioxidative peptide isolated from digests of a soybean protein
J. Agric. Food Chem., 44(9), 2619-2623 (1996).

 

Y. Zhang, K. Muramoto and F. Yamauchi
Hydrolysis of soybean proteins by a vortex flow filtration membrane reactor with Aspergillus oryzae proteases
J. Food Sci., 61(5), 928-931 (1996).

 

Y. Wako, S. Ishikawa and K. Muramoto
Angiotensin I-converting enzyme inhibitors in autolysate of squid liver and mantle muscle
Biosci. Biotech. Biochem., 60(8), 1353-1355 (1996).

 

R. Goto-Nance, K. Muramoto, Y. Zenpo and H. Kamiya
Purification and characterization of the lectins of the soft coral Lobophytum variatum
Fish. Sci., 62(2), 297-301 (1996).

 

M. Zhao, R. J. Naude, K. Muramoto and W. Oelofsen
Purification and characterization of ostrich pancreatic secretory trypsin inhibitor
Int J. Protein Peptide Res., 48, 174-181 (1996).

 

M. Toda, R. Goto-Nance, K. Muramoto and H. Kamiya
Characterization of the lectin from the skin mucus of the kingklip Genypterus capensis
Fish. Sci., 62(1), 138-141 (1996).

 

G. Bradley, Ryno J. Naude, K. Muramoto, F. Yamauchi and W. Oelofsen
Ostrich (Struthio Camelus) carboxypeptidase B: Purification, kinetic properties and characterization of the pancreatic enzyme,

Int. J. Biochem. Cell Biol., 28(5), 521-529 (1996).

 

K. Muramoto, T. Kuriki, K. Nokihara, H. Yako and H. Kamiya
Analysis of the hemolymph proteins from the acorn barnacle Megabalanus rosa by two-dimensional gel electrophoresis
Fish. Sci., 62(3), 435-438 (1996).

 

村本光二,陳華敏,山内文男:大豆たん白質由来抗酸化ペプチドの構造と機能の相関性
大豆たん白質研究会会誌,17,23-28(1996).

 

  Publications 1995

 N. Takamatsu, T. Shiba, K. Muramoto and H. Kamiya
Molecular cloning of the defense factor in the albumen gland of the sea hare Aplysia kurodai
FEBS Lett., 377, 373-376 (1995).

 

B.I. Pletschke, R. J. Naud, W. Oelofsen, K. Muramoto and F. Yamauchi
Ostrich pepsinogens I and II: Purification, activation and chemical and immunochemical characterization of the enzymes from the proventriculus
Int. J. Biochem. Cell Biol., 27(6), 613-624 (1995).

 

K. Sudo, W. Choorit, I. Asami, J. Kaneko, K. Muramoto and Y. Kamio
Substitution of lysine for arginine in the N-terminal 217th amino acid residue of the HgII of Staphylococcal g-hemolysin lowers the acitivity of the toxin
Biosci. Biotech. Biochem., 59(9), 1786-1789 (1995).

 

H. -M. Chen, K. Muramoto and F. Yamauchi
Structural analysis of antioxidative peptides from soybean b conglycinin
J. Agric. Food Chem., 43, 574-578 (1995).

 

K. Muramoto, T. Matsuda, K. Nakada and H. Kamiya
Occurrence of multiple lectins in the hemolymph of kuruma prawn Penaeus japonicus
Fish. Sci., 61(1), 131-136 (1995).

 

W. Choori, J. Kaneko, K. Muramoto and Y. Kamio
Existence of a new protein component with the same function as the LukF component of leukocidin or g-hemolysin and its gene in Staphylococcus aureus p83
FEBS Lett., 357, 260-264 (1995).

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東北大学大学院生命科学研究科分子生命科学専攻

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