Original papers (mainly worked in our laboratory)

(* Equally contributed)

The PDR-type ABC transporters AtrA and AtrG are involved in azole drug resistance in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2018, 82(10): 1840-1848.

Daisuke Miura, Kohei Sugiyama, Atsushi Ito, Ayumi Ohba-Tnaka, Mizuki Tanaka1, Takahiro Shintani, and Katsuya Gomi.

(1 University of Shizuoka)

Nuclear export‐dependent degradation of the carbon catabolite repressor CreA is regulated by a region located near the C‐terminus in Aspergillus oryzae.

Molecular Microbiology, 2018, 110(2): 170-196.

Mizuki Tanaka1, Sakurako Ichinose, Takahiro Shintani, and Katsuya Gomi.

(1 University of Shizuoka)

The C-terminal region of the yeast monocarboxylate transporter Jen1 acts as a glucose signal-responding degron recognized by the α-arrestin Rod1.

Journal of Biological Chemistry, 2018, 293(28):10926-10936.

Shoki Fujita, Daichi Sato, Hirokazu Kasai, Masataka Ohashi, Shintaro Tsukue, Yutaro Takekoshi, Katsuya Gomi, and Takahiro Shintani.

Chaperone complex formation of the transcription factor MalR involved in maltose utilization and amylolytic enzyme production in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2018, 8: 1-9.

Yui Konno, Kuta Suzuki, Mizuki Tanaka1, Takahiro Shintani, and Katsuya Gomi.

(1 University of Shizuoka)

Subcellular localization of aphidicolin biosynthetic enzymes hrterologously expressed in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2018, 82(1): 139-147.

Ban Akihiko, Mizuki Tanaka1, Ryuya Fujii2, Atsushi Minami2, Hideki Oikawa2, Takahiro Shintani, and Katsuya Gomi.

(1 University of Shizuoka, 2 Hokkaido University)

Increased production of biomass-degrading enzymes by double deletion of creA and creB genes involved in carbon catabolite repression in Aspergillus oryzae.

Journal of Bioscience and Bioengineering, 2018, 125(2): 141-147.

Ichinose Sakurako, Mizuki Tanaka, Takahiro Shintani, and Katsuya Gomi.

Improved α-Amylase Production by Dephosphorylation Mutation of CreD, an Arrestin-like Protein Required for Glucose-induced Endocytosis of Maltose Permease and Carbon Catabolite De-repression in Aspergillus oryzae.

Applied and Environmental Microbiology, 2017, 83(13): e00592-e00617.

Mizuki Tanaka, Tetsuya Hiramoto, Hinako Tada, Takahiro Shintani, and Katsuya Gomi.

Cell wall α-1,3-glucan prevents α-amylase adsorption onto fungal cell in submerged culture of Aspergillus oryzae.

Journal of Bioscience and Bioengineering, 2017, 124(1): 47-53.

Silai Zhang, Hiroki Sato, Sakurako Ichinose, Mizuki Tanaka, Ken Miyazawa1, Akira Yoshimi1, Keietsu Abe1, Takahiro Shintani, Katsuya Gomi.

(1 Tohoku University)

Cellular responses to the expression of unstable secretory proteins in the filamentous fungus Aspergillus oryzae.

Applied Microbiology and Biotechnology, 2017, 101(3): 2437-2446.

Jun-ichi Yokota*, Daisuke Shiro*, Mizuki Tanaka, Yasumichi Onozaki, Osamu Mizutani, Dararat Kakizono, Sakurako Ichinose, Tomoko Shintani, Katsuya Gomi, and Takahiro Shintani.

A novel Zn2-Cys6 transcription factor AtrR plays a key role in an azole resistance mechanism of Aspergillus fumigatus by co-regulating cyp51A and cbr1B expressions.

PLoS Pathogens, 2017, 13(1): e1006096.

Daisuke Hagiwara*1, Daisuke Miura*, Kiminori Shimizu1, Sanjoy Paul2, Ayumi Ohba, Tohru Gonoi1, Akira Watanabe1, Katsuhiko Kamei1, Takahiro Shintani, W. Scott Moye-Rowley2, Susumu Kawamoto1, and Katsuya Gomi.

(1 Chiba University, 2 University of iowa)

Induction of autophagy by phosphate starvation in an Atg11-dependent manner in Saccharomyces cerevisiae.

Biochemical and Biophysical Research Communications, 2017, 483(1): 522-527.

Hiroto Yokota, Katsuya Gomi, and Takahiro Shintani.

Self-excising Cre/mutant lox marker recycling system for multiple gene integrations and consecutive gene deletions in Aspergillus oryzae.

Journal of Bioscience and Bioengineering, 2017, 123(4): 403-411.

Silai Zhang, Akihiko Ban, Naoki Ebara, Osamu Mizutani, Mizuki Tanaka, Takahiro Shintani, and Katsuya Gomi.

The C2H2-type transcription factor, FlbC, is involved in the transcriptional regulation of Aspergillus oryzae glucoamylase and protease genes specifically expressed in solid-state culture.

Applied Microbiology and Biotechnology, 2016, 100(13): 5859-5868.

Mizuki Tanaka*, Midori Yoshimura*, Masahiro Ogawa, Yasuji Koyama, Takahiro Shintani, and Katsuya Gomi.

Unfolded protein response is required for Aspergillus oryzae growth under conditions inducing secretory hydrolytic enzyme production.

Fungal Genetics and Biology, 2015, 85: 1-6.

Mizuki Tanaka, Takahiro Shintani, and Katsuya Gomi.

Purification and enzymatic characterization of a novel β-1,6-glucosidase from Aspergillus oryzae.

Journal of Bioscience and Bioengineering, 2016, 121(3): 259-264.

Akira Watanabe, Moe Suzuki, Seiryu Ujiie, and Katsuya Gomi.

Endocytosis of a maltose permease is induced when amylolytic enzyme production is repressed in Aspergillus oryzae.

Fungal Genetics and Biology, 2015, 82: 136-144.

Tetsuya Hiramoto*, Mizuki Tanaka*, Takanori Ichikawa, Yuka Matsuura, Sachiko Hasegawa-Shiro, Takahiro Shintani, and Katsuya Gomi.

Purification and enzymatic characterization of secretory glycoside hydrolase family 3 (GH3) aryl β-glucosidases screened from Aspergillus oryzae genome.

Journal of Bioscience and Bioengineering, 2015, 120(6): 614-623.

Kanako Kudo*, Akira Watanabe*, Seiryu Ujiie, Takahiro Shintani, and Katsuya Gomi.

Distinct mechanism of activation of two transcription factors, AmyR and MalR, involved in amylolytic enzyme production in Aspergillus oryzae.

Applied Microbiology and Biotechnology, 2015, 99(4): 1805-1815.

Kuta Suzuki*, Mizuki Tanaka*, Yui Konno, Takanori Ichikawa, Sakurako Ichinose, Sachiko Hasegawa-Shiro, Takahiro Shintani, and Katsuya Gomi.

Fusion of an intact secretory protein permits a misfolded protein to exit from the endoplasmic reticulum in yeast.

Bioscience, Biotechnology, and Biochemistry, 2014, 78(1): 49-59.

Kengo Suyama, Mizue Hori, Katsuya Gomi, and Takahiro Shintani.

Evaluation of baker’s yeast strains exhibiting significant growth on Japanese beet molasses and compound analysis of the molasses types.

Journal of Bioscience and Bioengineering, 2014, 117(6): 715-719.

Hiroaki Nakata, Masahiko Tamura, Takahiro Shintani, and Katsuya Gomi.

Improved α-amylase production by Aspergillus oryzae after a double deletion of genes involved in carbon catabolite repression.

Applied Microbiology and Biotechnology, 2014, 98(1): 335-343.

Sakurako Ichinose*, Mizuki Tanaka*, Takahiro Shintani, and Katsuya Gomi.

Transcripts of a heterologous gene encoding mite allergen Der f 7 are stabilized by codon optimization in Aspergillus oryzae.

Applied Microbiology and Biotechnology, 2012, 96(5): 1275-1282.

Mizuki Tanaka, Masafumi Tokuoka, Takahiro Shintani, and Katsuya Gomi.

Functional analysis of FarA transcription factor in the regulation of the genes encoding lipolytic enzymes and hydrophobic surface binding protein for the degradation of biodegradable plastics in Aspergillus oryzae.

Journal of Bioscience and Bioengineering, 2012, 113(5): 549-555.

Sharon Marie Garrido, Noriyuki Kitamoto, Akira Watanabe, Takahiro Shintani, and Katsuya Gomi.

Identification of potential cell wall component that allows Taka-amylase A adsorption in submerged cultures of Aspergillus oryzae.

Applied Microbiology and Biotechnology, 2011, 92(5): 961-969.

Hiroki Sato, Yoshiyuki Toyoshima, Takahiro Shintani, and Katsuya Gomi.

In silico analysis of 3´-end-processing signals in Aspergillus oryzae using expressed sequence tags and genomic sequencing data.

DNA Research, 2011, 18(3): 189-200.

Mizuki Tanaka*, Yoshifumi Sakai*, Osamu Yamada, Takahiro Shintani, and Katsuya Gomi.

Aspartyl aminopeptidase is imported from the cytoplasm to the vacuole by selective autophagy in Saccharomyces cerevisiae.

Journal of Biological Chemistry, 2011, 286(15): 13704-13.

Masaki Yuga, Katsuya Gomi, Daniel J. Klionsky, and Takahiro Shintani.

Heterologous expression of Aspergillus oryzae xylose reductase and xylitol dehydrogenase genes facilitated xylose utilization in the yeast Saccharomyces cerevisiae.

Bioscience, Biotechnology, and Biochemistry, 2011. 75(1): 168-170.

Jitsuro Kaneda, Kenji Sasaki, Katsuya Gomi, and Takahiro Shintani.

Characterization and expression analysis of a maltose-utilizing (MAL) cluster in Aspergillus oryzae.

Fungal Genetics and  Biology, 2010, 47(1): 1-9.

Sachiko Hasegawa, Masahiro Takizawa, Haruhiko Suyama, Takahiro Shintani, and Katsuya Gomi.

Aspergillus oryzae atfA controls conidial germination and stress tolerance.

Fungal Genetics and  Biology, 2009, 46(12): 887-97.

Kazutoshi Sakamoto, Kazuhiro Iwashita, Osamu Yamada, Ken Kobayashi, Akihiro Mizuno, Osamu Akita, Shigeaki Mikami, Hitoshi Shimoi, and Katsuya Gomi.

Crawler, a novel Tc1/mariner-type transposable element in Aspergillus oryzae transposes under stress conditions.

Fungal Genetics and Biology, 2009, 46(6):441-449.

Hironobu Ogasawara, Hiroshi Obata, Yoji Hata, Saori Takahashi, and Katsuya Gomi.

Codon optimization increases steady-state mRNA levels in Aspergillus oryzae heterologous gene expression.

Applied and Environmental Microbiology, 2008, 74(21): 6538-46.

Masafumi Tokuoka, Mizuki Tanaka, Kazuhisa Ono, Shinobu Takagi, Takahiro Shintani, and Katsuya Gomi.

A defect of LigD (human Lig4 homolog) for nonhomologous end joining significantly improves efficiency of gene-targeting in Aspergillus oryzae.

Fungal Genetics and Biology, 2008, 45(6): 878-89.

Osamu Mizutani*, Youhei Kudo*, Akemi Saito, Tomomi Matsuura, Hirokazu Inoue, Keietsu Abe, and Katsuya Gomi.

Aspergillus oryzae atfB encodes a transcription factor required for stress tolerance in conidia.

Fungal Genetics and Biology, 2008, 45(6):922-32.

Kazutoshi Sakamoto, Toshi-hide Arima, Kazuhiro Iwashita, Osamu Yamada, Katsuya Gomi, and Osamu Akita.

Original papers (Others)

Katsuya Gomi (1993-)

Heterologous Biosynthesis of Fungal Indole Sesquiterpene Sespendole.

ChemBioChem, 2018, 19: 1-7.

Kosei Kudo, Chengwei Liu, Tomoyuki Matsumoto, Atsushi Minami, Taro Ozaki, Hiroaki Toshima, Katsuya Gomi, and Hideki Oikawa.

Heterologous Production of a Novel Cyclic Peptide Compound, KK-1, in Aspergillus oryzae.

Frontiers in Microbiology, 2018, 9: 690.

Akira Yoshimi, Shigenari Yamaguchi, Tomonori Fujioka, Kiyoshi Kawai, Katsuya Gomi, Mayayuki machida, and Keietsu Abe.

Biosynthetic Machinery of Diterpene Pleuromutilin Isolated from Basidiomycete Fungi.

ChemBioChem, 2017, 18(23): 2317-2322.

Momoka Yamane, Atsushi Minami, Chengwei Liu, Taro Ozaki, Ichiro Takeuchi, Tae Tsukagoshi, Tetsuo Tokiwano, Katsuya Gomi, Hideki Oikawa.

Quantitative evaluation of haze formation of koji and progression of internal haze by drying of koji during koji making.

Journal of Bioscience and Bioengineering, 2017, 124(1): 62-70.

Kazunari Ito, Katsuya Gomi, Masahiro Kariyama, Tsuyoshi Miyake.

Genome sequence of Aspergillus luchuensis NBRC 4314.

DNA Research, 2016, 23(6): 507-515.

Yamada O, Machida M, Hosoyama A, Goto M, Takahashi T, Futagami T, Yamagata Y, Takeuchi M, Kobayashi T, Koike H, Abe K, Asai K, Arita M, Fujita N, Fukuda K, Higa KI, Horikawa H, Ishikawa T, Jinno K, Kato Y, Kirimura K, Mizutani O, Nakasone K, Sano M, Shiraishi Y, Tsukahara M, and Gomi K.

Biosynthesis of shearinine: diversification of a tandem prenyl moiety of fungal indole diterpenes.

Organic Letters, 2016, 18(19): 5026-5029.

Liu C, Minami A, Dairi T, Gomi K, Scott B, and Oikawa H.

Increased enzyme production under liquid culture conditions in the industrial fungus Aspergillus oryzae by disruption of the genes encoding cell wall α-1,3-glucan synthase.

Bioscience, Biotechnology, and Biochemistry, 2016, 80(9): 1853-1863.

Miyazawa K,  Yoshimi A, Zhang S, Sano M, Nakayama M, Gomi K, Abe K.

Genome mining approach for harnessing the cryptic gene cluster in Alternaria solani: production of PKS-NRPS hybrid metabolite, didymellamide B.

Tetrahedron Letters, 2016, 57(25): 2793-2796.

Ugai T, Minami A, Gomi K, and Oikawa H.

Unveiling the Biosynthetic Pathway of the Ribosomally Synthesized and Post-translationally Modified Peptide Ustiloxin B in Filamentous Fungi.

Angewandte Chemle International Edition, 2016, 55(28): 8072-8075.

Ye Y, Minami A, Igarashi Y, Izumikawa M, Umemura M, Nagano N, Machida M, Kawahara T, Shin-Ya K, Gomi K, and Oikawa H.

Multiple Oxidative Modifications in the Ophiobolin Biosynthesis: P450 Oxidations Found in Genome Mining.

Organic Letters, 2016, 18(9): 1980-1983.

Narita K, Chiba R, Minami A, Kodama M, Fujii I, Gomi K, and Oikawa H.

Substantial decrease in cell wall α-1,3-glucan caused by disruption of the kexB gene encoding a subtilisin-like processing protease in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2016, 80(9): 1781-1791.

Mizutani O, Shiina M, Yoshimi A, Sano M, Watanabe T, Yamagata Y, Nakajima T, Gomi K, Abe K.

Biosynthetic study on antihypercholesterolemic agent phomoidride: general biogenesis of fungal dimeric anhydrides.

Organic Letters, 2015, 17(22): 5658-5661.

Fujii R, Matsu Y, Minami A, Nagamine S, Takeuchi I, Gomi K, and Oikawa H.

Reconstitution of biosynthetic machinery of fungal polyketides: unexpected oxidations of biosynthetic intermediates by expression host.

Bioscience, Biotechnology, and Biochemistry, 2016, 80(3): 426-431.

Fujii R, Ugai T, Ichinose H, Hatakeyama M, Kosaki T, Gomi K, Fujii I, Minami A, and Oikawa H.

Genome mining for sesterterpenes using bifunctional terpene syntheses reveals a unified intermediate of di/sesterterpenes.

Journal of the American Chemical Society, 2015, 137(36): 11846-11853.

Ye Y, Minami A, Mándi A, Liu C, Taniguchi T, Kuzuyama T, Monde K, Gomi K, and Oikawa H.

Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides.

Nature Chemistry, 2015, 7(9): 737-743.

Asai T, Tsukada K, Ise S, Shirata N, Hashimoto M, Fujii I, Gomi K, Nakagawara K, Kodama EN, and Oshima Y.

Reconstitution of biosynthetic machinery for the synthesis of the highly elaborated indole diterpene penitrem.

Angewandte Chemle International Edition, 2015, 54(19): 5748-5752.

Liu C, Tagami K, Minami A, Matsumoto T, Frisvad JC, Suzuki H, Ishikawa J, Gomi K, and Oikawa H.

Heterologous expression of highly reducing polyketide synthase involved in betanone biosynthesis.

Chemical Communications, 2015, 51(10): 1878-1891.

Ugai T, Minami A, Fujii R,  Tanaka M, Oguri H, Gomi K, and Oikawa H.

Change in enzyme production by gradually drying culture substrate during solid-state fermentation.

Journal of Bioscience and Bioengineering, 2015, 119(6): 674-677.

Ito K, Gomi K, Kariyama M, and Miyake T.

Rapid reconstitution of biosynthetic machinery for fungal metabolites in Aspergillus oryzae: total biosynthesis of aflatrem.

ChemBioChem, 2014, 15(14): 2076-2080.

Tagami K, Minami A, Fujii R, Liu C, Tanaka M, Gomi K, Dairi T, and Oikawa H.

Structurally diverse chaetophenol productions induced by chemically mediated epigenetic manipulation if fungal gene expression.

Organic Letters, 2013, 15(13): 3346-3349.

Asai T, Yamamoto T, Shirata N, Taniguchi T, Monde K, Fujii I, Gomi K, and Oshima Y.

Rapid enzyme production and mycelial growth in solid-state fermentation using the non-airflow box.

Journal of Bioscience and Bioengineering, 2013, 116(5): 585-590.

Ito K, Gomi K, Kariyama M, and Miyake T.

Aspergillus luchuensis, an industrially important black Aspergillus in East Asia.

PLoS One, 2013, 8(5): e63769.

Hong SB, Lee M, Kim DH, Varga J, Frisvad JC, Perrone G, Gomi K, Yamada O, Machida M, Houbraken J, and Samson RA.

Biosynthetic assembly of cytochalasin backbone.

Tetrahedron Letters, 2013, 54(23): 2999-3002.

Fujii R, Minami A, Gomi K, and Oikawa H.

Identification of ophilobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus.

Organic Letters, 2013, 15(3): 594-597.

Chiba R, Minami A, Gomi K, and Oikawa H.

Reconstitution of biosynthetic machinery for indole-diterpene paxilline in Aspergillus oryzae.

Journal of the American Chemical Society, 2013, 135(4): 1260-1263.

Tagami K, Liu C, Minami A, Noike M, Isaka T, Fueki S, Shichijo Y, Toshima H, Gomi K, Dairi T, and Oikawa H.

Modified Cre-loxP recombination in Aspergillus oryzae by direct introduction of Cre recombinase for marker gene rescue.

Applied and Environmental Microbiology, 2012, 78(12): 4126-4133.

Mizutani O, Masaki K, Gomi K, and Iefuji H.

Total biosynthesis of diterpene aphidicolin, a specific inhibitor of DNA polymerase α: heterologous expression of four biosynthetic genes in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2011, 75(9): 1813-1817.

Fujii R, Minami A, Tsukagoshi T, Sato N, Sahara T, Ohgiya S, Gomi K, and Oikawa H.

Construction of a thiamine pyrophosphate high-producing strain of Aspergillus oryzae by overexpression of three genes involved in thiamine biosynthesis.

Journal of Bioscience and Bioengineering, 2011,111(4): 388-390.

Misato Tokui, Takafumi Kubodera, Katsuya Gomi, Nobuo Yamashita, and Akira Nishimura.

Uniform culture in solid-state fermentation with fungi and its efficient enzyme production.

Journal of Bioscience and Bioengineering, 2011, 111(3): 300-305.

Kazunari Ito, Tomoka Kawase, Hiroyuki Sammoto, Katsuya Gomi, Masahiro Kariyama, and Tsuyoshi Miyake.

Alternative processing of proproteins in Aspergilli kexB gene disruptants under hyperosmotic conditions.

Bioscience, Biotechnology, and Biochemistry, 2009, 73(1): 40-46.

Mizutani O, Furukawa K, Ichiyanagi S, Matsuda Y, Tokuoka M, Fujioka T, Yamagata Y, Gomi K, Abe K.

Analysis of expressed sequence tags from the fungus Aspergillus oryzae cultured under different conditions.

DNA Research, 2007, 14(2): 47-57.

Akao T, Sano M, Yamada O, Akeno T, Fujii K, Goto K, Ohashi-Kunihiro S, Takase K, Yasukawa-Watanabe M, Yamaguchi K, Kurihara Y, Maruyama J, Juvvadi PR, Tanaka A, Hata Y, Koyama Y, Yamaguchi S, Kitamoto N, Gomi K, Abe K, Takeuchi M, Kobayashi T, Horiuchi H, Kitamoto K, Kashiwagi Y, Machida M, and Akita O.

Novel hydrophobic surface binding protein, HsbA, produced by Aspergillus oryzae.

Applied and Environmental Microbiology, 2006, 72(4): 2707-2713.

Ohtaki S, Maeda H, Takahashi T, Yamagata Y, Hasegawa F, Gomi K, NakajimaT, and Abe K.

Genome sequencing and analysis of Aspergillus oryzae.

Nature, 2005, 438(7071): 1157-61.

Machida M, Asai K, Sano M, Tanaka T, Kumagai T, Terai G, Kusumoto K, Arima T, Akita O, Kashiwagi Y, Abe K, Gomi K, Horiuchi H, Kitamoto K, Kobayashi T, Takeuchi M, Denning DW, Galagan JE, Nierman WC, Yu J, Archer DB, Bennett JW, Bhatnagar D, Cleveland TE, Fedorova ND, Gotoh O, Horikawa H, Hosoyama A, Ichinomiya M, Igarashi R, Iwashita K, Juvvadi PR, Kato M, Kato Y, Kin T, Kokubun A, Maeda H, Maeyama N, Maruyama J, Nagasaki H, Nakajima T, Oda K, Okada K, Paulsen I, Sakamoto K, Sawano T, Takahashi M, Takase K, Terabayashi Y, Wortman JR, Yamada O, Yamagata Y, Anazawa H, Hata Y, Koide Y, Komori T, Koyama Y, Minetoki T, Suharnan S, Tanaka A, Isono K, Kuhara S, Ogasawara N, and Kikuchi H.

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus.

Nature, 2005, 438(7071): 1151-1156.

Nierman WC, Pain A, Anderson MJ, Wortman JR, Kim HS, Arroyo J, Berriman M, Abe K, Archer DB, Bermejo C, Bennett J, Bowyer P, Chen D, Collins M, Coulsen R, Davies R, Dyer PS, Farman M, Fedorova N, Fedorova N, Feldblyum TV, Fischer R, Fosker N, Fraser A, Garcia JL, Garcia MJ, Goble A, Goldman GH, Gomi K, Griffith-Jones S, Gwilliam R, Haas B, Haas H, Harris D, Horiuchi H, Huang J, Humphray S, Jimenez J, Keller N, Khouri H, Kitamoto K, Kobayashi T, Konzack S, Kulkarni R, Kumagai T, Lafton A, Latge JP, Li W, Lord A, Lu C, Majoros WH, May GS, Miller BL, Mohamoud Y, Molina M, Monod M, Mouyna I, Mulligan S, Murphy L, O'neil S, Paulsen I, Penalva MA, Pertea M, Price C, Pritchard BL, Quail MA, Rabbinowitsch E, Rawlins N, Rajandream MA, Reichard U, Renauld H, Robson GD, de Cordoba SR, Rodriguez-Pena JM, Ronning CM, Rutter S, Salzberg SL, Sanchez M, Sanchez-Ferrero JC, Saunders D, Seeger K, Squares R, Squares S, Takeuchi M, Tekaia F, Turner G, de Aldana CR, Weidman J, White O, Woodward J, Yu JH, Fraser C, Galagan JE, Asai K, Machida M, Hall N, Barrell B, Denning DW

The fungal hydrophobin RolA recruits polyesterase and laterally moves on hydrophobic surfaces.

Molecular Microbiology, 2005, 57(6): 1780-1796.

Takahashi T, Maeda H, Yoneda S, Ohtaki S, Yamagata Y, Hasegawa F, Gomi K, Nakajima T, and Abe K.

Purification and characterization of a biodegradable plastic-degrading enzyme from Aspergillus oryzae.

Applied Microbiology and Biotechnology,2005, 67(6): 778-788.

Maeda H, Yamagata Y*, Abe K, Hasegawa F, Machida M, Ishioka R, Gomi K, and Nakajima T.

Transcriptional analysis of genes for energy catabolism and hydrolytic enzymes in the filamentous fungus Aspergillus oryzae using cDNA microarrays and expressed sequence tags.

Applied Microbiology and Biotechnology, 2004, 65(1): 74-83.

Maeda H, Sano M, Maruyama Y, Tanno T, Akao T, Totsuka Y, Endo M, Sakurada R, Yamagata Y, Machida M, Akita O, Hasegawa F, Abe K, Gomi K, Nakajima T, and Iguchi Y.

Thiamine-regulated gene expression of Aspergillus oryzae thiA requires splicing of the intron containing a riboswitch-like domain in the 5'-UTR.

FEBS Letters, 2003, 555(3): 516-520.

Kubodera T, Watanabe M, Yoshiuchi K, Yamashita N, Nishimura A, Nakai S, Gomi K, and Hanamoto H.

chsZ, a gene for a novel class of chitin synthase from Aspergillus oryzae.

Current Genetics, 2002, 41(4): 261-267.

Chigira Y, Abe K, Gomi K, and Nakajima T.

Subtractive cloning of cDNA from Aspergillus oryzae differentially regulated between solid-state culture and liquid (submerged) culture.

Current Genetics, 2002, 41(4): 275-281.

Akao T, Gomi K, Goto K, Okazaki N, and Akita O.

Cloning, nucleotide sequencing, and expression of the beta-galactosidase-encoding gene (lacA) from Aspergillus oryzae.

Journal of General and Applied Microbiology, 2002, 48(3): 135-142.

Ito Y, Sasaki T, Kitamoto K, Kumagai C, Takahashi K, Gomi K, and Tamura G.

Deletion analysis of the enolase gene (enoA) promoter from the filamentous fungus Aspegillus oryzae.

Current Genetics, 2001, 40(4): 260-267.

Toda T, Sano M, Honda M, Rimoldi OJ, Yang Y, Yamamoto M, Takase K, Hirozumi K, Kitamoto K, Minetoki T, Gomi K, and Machida M.

Characterization of the amyR gene encoding a transcriptional activator for the amylase genes in Aspergillus nidulans.

Current Genetics, 2001, 39: 10-15.

Tani S, Katsuyama Y, Hayashi T, Suzuki H, Kato M, Gomi K, Kobayashi T, and Tsukagoshi N.

High-level secretory production of phospholipase Al by Saccharomyces cerevisiae and Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2001, 65: 94-101.

Shiba Y, Ono C, Fukui F, Watanabe I, Serizawa N, Gomi K, and Yoshikawa H

Rapid detection of homologously integrated DNA fragments and accurate quantitation of their copy number in transgenic Aspergillus oryzae by PCR.

Journal of Bioscience and Bioengineering, 2000, 90(5): 577-579.

Honda M, Minetoki T, Gomi K, and Machida M.

Molecular cloning and characterization of a transcriptional activator gene, amyR, involved in the amylolytic gene expression in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 2000, 64(4): 816-827.

Gomi K, Akeno T, Minetoki T, Ozeki K, Kumagai C, Okazaki N, and Iimura Y.

Molecular and enzymic properties of recombinant 1,2-alpha-mannosidase from Aspergillus saitoi overexpressed in Aspergillus oryzae cells.

Biochemical Journal, 1999, 339(3): 589-597.

Ichishima E, Taya N, Ikeguchi M, Chiba Y, Nakamura M, Kawabata C, Inoue T, Takahashi K, Minetoki T, Ozeki K, Kumagai C, Gomi K, Yoshida T, and Nakajima T.

Cloning and functional analysis of the Aspergillus oryzae conidiation regulator gene brlA by its disruption and missheduled expression.

Journal of Bioscience and Bioengineering, 1999, 87(4): 424-429.

Yamada O, Lee BR, Gomi K, and Iimura Y.

An aureobasidin A resistance gene isolated from Aspergillus is a homolog of yeast AUR1, a gene responsible for inositol phosphorylceramide (IPC) synthase activity.

Molecular and General Genetics, 1999, 261(2): 290-296.

Kuroda M, Hashida-Okado T, Yasumoto R, Gomi K, Kato I, and Takesako K.

Insertion analysis of putative functional elements in the promoter region of the  Aspergillus oryzae Taka-amylase A gene (amyB) using a heterologous Aspergillus nidulans amdS-lacZ fusion gene system.

Bioscience, Biotechnology, and Biochemistry, 1999, 63(1): 180-183.

Kanemori Y, Gomi K, Kitamoto K, Kumagai C, and Tamura G.

Differentiation of koji molds and their related aflatoxigenic fungi.

Mycotoxins, 1999, 49: 19-22.

Gomi K.

Improvement of promoter activity by the introduction of multiple copies of the conserved region III sequence, involved in the efficient expression of Aspergillus oryzae amylase-encoding genes.

Applied Microbiology and Biotechnology,1998, 50(4): 459-467.

Minetoki T, Kumagai C, Gomi K, Kitamoto K, and Takahashi K.

Transformation system for Aspergillus oryzae with double auxotrophic mutations, niaD and sC.

Bioscience, Biotechnology, and Biochemistry, 1997, 61: 1367-1369.

Yamada O, Lee BR, and Gomi K.

Deletion analysis of promoter elements of the Aspergillus oryzae agdA gene encoding α-glucosidase.

Current Genetics, 1998, 30(5): 432-438.

Minetoki T, Nunokawa Y, Gomi K, Kitamoto K, Kumagai C, Tamura G

Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-methylsalicylic acid synthase gene by heterologous expression.

Molecular and General Genetics, 1998, 253(1-2): 1-10

Fujii I, Ono Y, Tada H, Gomi K, Ebizuka Y, Sankawa U.

Molecular cloning of a genomic DNA for enolase from Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1996, 60(1): 161-163.

Machida M, Gonzalez TV, Boon LK, Gomi K, Jigami Y.

Characteristic expression of three amylase-encoding genes, agdA, amyB, and glaA in Aspergillus oryzae transformants containing multiple copies of the agdA gene.

Bioscience, Biotechnology, and Biochemistry, 1995, 59(12): 2252-2254.

Minetoki T, Gomi K, Kitamoto K, Kumagai C, Tamura G.

Cloning and nucleotide sequence of the ribonuclease T1 gene (rntA) from Aspergillus oryzae and its expression in Saccharomyces cerevisiae and Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1995, 59(10): 1869-1874.

Fujii T, Yamaoka H, Gomi K, Kitamoto K, Kumagai C.

Molecular cloning and heterologous expression of the gene encoding dihydrogeodin oxidase, a multicopper blue enzyme from Aspergillus terreus.

Journal of Biological Chemistry, 1997, 270(37): 21495-21502.

Huang KX, Fujii I, Ebizuka Y, Gomi K, Sankawa U.

Nucleotide sequence and expression of α-glucosidase-encoding gene (agdA) from Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1995, 59(8): 1516-1521.

Minetoki T, Gomi K, Kitamoto K, Kumagai C, Tamura G.

Cloning and nucleotide sequence of the calmodulin-encoding gene (cmdA) from Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1995, 59(8): 1444-1449.

Yasui K, Kitamoto K, Gomi K, Kumagai C, Ohya Y, Tamura G.

Electrophoretic karyotype and gene assignment to chromosomes of Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1994, 58(8): 1467-1470.

Kitamoto K, Kimura K, Gomi K, Kumagai C.

A novel culture method for high level production of heterologous protein in Saccharomyces cerevisiae.

Bioscience, Biotechnology, and Biochemistry, 1994, 58(7): 1292-1296.

Nagashima T, Yamamoto Y, Gomi K, Kitamoto K, Kumagai C.

High level secretion of calf chymosin using a glucoamylase-prochymosin fusion gene in Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1994, 58(5): 895-899.

Tsuchiya K, Nagashima T, Yamamoto Y, Gomi K, Kitamoto K, Kumagai C, Tamura G.

Secretion of calf chymosin from the filamentous fungus Aspergillus oryzae.

Applied Microbiology and Biotechnology, 1993, 40(2-3): 327-332.

Tsuchiya K, Gomi K, Kitamoto K, Kumagai C, Tamura G.

Cloning and nucleotide sequence of the acid protease-encoding gene(pepA) from Aspergillus oryzae.

Bioscience, Biotechnology, and Biochemistry, 1993, 57(7): 1095-1100.

Gomi K, Arikawa K, Kamiya N, Kitamoto K, Kumagai C.

Takahiro Shintani

Quantitative regulation of histone variant H2A.Z during cell cycle by ubiquitin proteasome system and SUMO-targeted ubiquitin ligases.

Bioscience, Biotechnology, and Biochemistry, 2017, 81(8): 1557-1560.

Takahashi D, Orihara Y, Kitagawa S, Kusakabe M, Shintani T, Oma Y, Harata M.

The conserved oligomeric Golgi complex is involved in double-membrane vesicle formation during autophagy.

Journal of Cell Biology, 2010, 188(1): 101-114.

Yen WL, Shintani T, Nair U, Cao Y, Richardson BC, Li Z, Hughson FM, Baba M, and Klionsky DJ.

Atg11 directs autophagosome cargoes to the PAS along actin cables.

Autophagy, 2006, 2: 119-121.

Iryna Monastyrska, Takahiro Shintani, Daniel J. Klionsky and Fulvio Reggiori.

Atg9 cycles between mitochondria and the Pre-autophagosomal structure in yeasts.

Autophagy, 2005, 1: 101-109.

Fulvio Reggiori, Takahiro Shintani, Usha Nair, and Daniel J. Klionsky.

The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae.

Molecular Biology of the Cell, 2005. 16: 5843-5856.

Fulvio Reggiori, Iryna Monastyrska, Takahiro Shintani, and Daniel J. Klionsky.

Cargo proteins facilitate the formation of transport vesicles in the cytoplasm to vacuole targeting pathway.

Journal of Biological Chemistry, 2004, 279: 29889-29894.

Takahiro Shintani and Daniel J. Klionsky.

Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae.

Molecular Biology of the Cell, 2004, 15: 2189-2204.

Fulvio Reggiori, Chao-Wen Wang, Usha Nair, Takahiro Shintani, Hagai Abeliovich and Daniel J. Klionsky.

Vps51 is part of the yeast Vps fifty three tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion.

Journal of Biological Chemistry, 2003, 278: 5009-5020.

Fulvio Reggiori, Chao-Wen Wang, Per E. Stromhaug, Takahiro Shintani and Daniel J. Klionsky.

Mechanism of cargo selection in the cytoplasm to vacuole targeting pathway.

Developmental Cell, 2002, 3: 825-837.

Takahiro Shintani, Wei-Pang Huang, Per E. Stromhaug and Daniel J. Klionsky.

Apg2p functions in autophagosome formation on the perivacuolar structure.

Journal of Biological Chemistry, 2001, 276: 30452-30460.

Takahiro Shintani, Kuninori Suzuki, Yoshiaki Kamada, Takeshi Noda and Yoshinori Ohsumi.

Tor-mediated induction of autophagy via Apg1 protein kinase complex.

Journal of Cell Biology, 2000, 150: 1507-1513.

Yoshiaki Kamada, Tomoko Funakoshi, Takahiro Shintani, Kazuya Nagano, Mariko Ohsumi and Yoshinori Ohsumi

The Apg12 conjugation system essential for autophagy.

Molecular Biology of the Cell, 1999, 10: 232A-.

Mizushima N,  Shintani T, Noda T, Yoshimori T, Ohsumi M, and Ohsumi Y.

Apg10, a novel protein-conjugation enzyme essential for autophagy in yeast.

EMBO J, 1999, 18: 5234-5241.

Shintani T, Mizushima N, Ogawa Y, Matsuura A, Noda T,  and Ohsumi Y.

Engineering of porcine pepsin: alternation of S1 substrate specificity of pepsin to those of fungal aspartic proteinases by site-directed mutagenesis.

Journal of Biological Chemistry, 1997, 272: 18855-18861.

Shintani T, Nomura K, and Ichishima E.

Characterization of the S1 subsite specificity of aspergillopepsin I by site-directed mutagenesis.

Journal of Biochemistry, 1996, 120: 974-981.

Shintani T, Kobayashi M, and Ichishima E.

Primary structure of aspergillopepsin I deduced from nucleotide sequence of the gene and aspartic acid-76 in an essential active site of the enzyme for trypsinogen activation.

Biochimica et Biophysica Acta, 1994, 1204: 257-264.

Takahiro Shintani and Eiji Ichishima.

Akira Watanabe

Purification and characterization of a thermostable neutral metalloprotease I from Chloroflexus aurantiacus J-10-fl.

Bioscience, Biotechnology, and Biochemistry, 1993, 57(12): 2160-2165.

Watanabe A, Kamio Y, Kimura W, Izaki K.