Chemistry and Life Science

Food Function Analysis

Introduction

In this laboratory, we are investigating the role of lipid peroxides in food deterioration and cell damage in living organism. We have established methods to synthesize high-purity lipid peroxides and constructed analytical methods using Mass Spectrometry, enabling the accurate quantification of lipid peroxides at the isomeric level. Using these methods, we are aiming to determine the mechanism responsible for oxidative degradation in food products and the role of membrane lipids peroxidation in the development of degenerative diseases in humans (i.e., atherosclerosis, hyperglycemia, dementia, cancer). In research on functional food, we mainly focus on their absorption and metabolism in vivo, and by determining their effect on the regulation of gene expression and cell function modulation. To ensure the optimal effects of the food ingredients, we are also developing suitable processing technologies, such as production of powdered fish oils. In particular, functional compounds of interest include plasmalogen, vitamin E, carotenoids, curcuminoids, γ-oryzanol, polyphenols, aza-sugars, pyrroloquinoline quinones. 

Keywords

lipid peroxidation, plasmalogen, vitamin E, carotenoids, curcuminoids, γ-oryzanol, polyphenols, aza-sugars, lipid glycation/Maillard reaction, pyrroloquinoline quinones, powdered fish oils.

Staff