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Laboratory of Animal Breeding and Genetics, Graduate School of Agricultural Science, Tohoku University.

English

Laboratory of Animal Breeding and Genetics

From livestock for food production to guide dogs and companion animals, our aim is to enhance the genetic ability of animals that are useful to humankind by genetic selection. For this purpose, it is important to understand the genetic characteristics of each animal population, accurately estimate the genetic ability of individual animals, and create progeny with high genetic performance. In agriculture, livestock is very popular in Europe and North America, and animal breeding and genetics is positioned as the most important research field that supports livestock.

Our laboratory is one of the few laboratories in Japan whose research methods are based on quantitative genetics.

Our projects


Animal Breeding Theory

  • Efficient selection method to improve a ratio-defined character
  • Development of breeding system to improve economic traits in pigs

Pigs

  • Development of genetic evaluation method using meteorological data
  • Genetic evaluation and development of selection criteria for reproductive, meat quality, lifetime performance, and disease resistance traits in pigs
  • Genetic evaluation using information on genetic markers and microbiome in pigs

Cattle

  • Genetic evaluation and development of selection criteria for reproductive, meat production, meat quality, and methane-related traits in beef cattle
  • Genetic evaluation using information on genomic markers in beef cattle

Members新着情報

  • Staff (Please replace * with @)
    Professor
    Masahiro Satoh (masahiro.satoh.d5*tohoku.ac.jp)
    Associate Prof.
    Yoshinobu Uemoto (yoshinobu.uemoto.e7*tohoku.ac.jp)
  • Students
    Doctoral St.
    You Fukuzawa
    Doctoral St.
    Yuriko Saito
    Doctoral St.
    Rintaro Nagai
    Graduate St.
    Kazuki Kusaka
    Graduate St.
    Yuri Satake
    Graduate St.
    Koyo Hirano
    Undergraduate
    Changmin Lee
    Undergraduate
    Yuji Takita
    Undergraduate
    Toyoto Maruyama
    Undergraduate
    Yugo Mineshima

Publications (Peer viewed articles written in English)新着情報

・Uemoto Y, Katsura T, Endo Y, Tanaka K, Zhuang T, Urakawa M, Baba T, Yoshida G, Wang H, Kitazawa H, Shirakawa H, Nakamura T, Nochi T, Aso H. (2023) Genetic aspects of immunoglobulins and cyclophilin A in milk as potential indicators of mastitis resistance in Holstein cows. Journal of Dairy Science, in press.

・Uemoto Y, Tomaru T, Masuda M, Uchisawa K, Hashiba K, Nishikawa Y, Suzuki K, Kojima T, Suzuki T, Terada F. (2023) Exploring indicators of genetic selection using the sniffer method to reduce methane emissions from Holstein cows. Animal Bioscience, in press

・Ogawa S, Takahashi H, Satoh M. (2023) Genetic parameter estimation for pork production and litter performance traits of Landrace, Large White, and Duroc pigs in Japan. Journal of Animal Breeding and Genetics, early view. https://doi.org/10.1111/jbg.12814

・Shikida R, Kim M, Futohashi M, Nishihara K, Lee H, Suzuki Y, Baek Y, Masaki T, Ikuta K, Iwamoto E, Uemoto Y, Haga S, Terada F, Roh S. (2023) Physiological roles and regulation of hepatic angiopoietin-like protein 3 in Japanese Black cattle (Bos taurus) during the fattening period. Journal of Animal Science, skad198. https://doi.org/10.1093/jas/skad198

・Kinukawa M, Ito M, Uemoto Y, Ogino A, Haruta S, Kurogi K, Yasumori T, Watanabe T, Sasaki S, Naniwa Y, Uchiyama K, Togashi K. (2023) A potent allele marker related to low bull conception rate in Japanese Black bulls. Animal, 17(5): 100804. https://doi.org/10.1016/j.animal.2023.100804

・Uemoto Y, Ichinoseki K, Matsumoto T, Oka N, Takamori H, Kadowaki H, Kojima-Shibata C, Suzuki E, Okamura T, Aso H, Kitazawa H, Satoh M, Uenishi H, Suzuki K. (2023) Genome-wide detection of changes in allelic frequency in Landrace pigs selected for resistance to mycoplasma pneumonia of swine. Animal Science Journal, 94: e13827. https://doi.org/10.1111/asj.13827

・Wang H, Hui P, Uemoto Y, Ding Y, Yin Z, Bao W. (2023) Metabolomic and proteomic profiling of porcine intestinal epithelial cells infected with porcine epidemic diarrhea virus. International Journal of Molecular Sciences, 24: 5071. https://doi.org/10.3390/ijms24065071

・Arakawa S, Kim M, Aonuma T, Takagi M, Watanabe S, Lee H, Nishihara K, Haga S, Uemoto Y, Roh S. (2023) Characteristics of physiological parameters of Japanese Black calves relate to carcass weight. Animals, 13(3): 487. https://doi.org/10.3390/ani13030487

・Ogawa S, Ohnishi C, Satoh M. (2022) Effect of ambient temperature on average daily gain of pigs evaluated using public weather data and a plateau-linear regression model. Animal Science Journal 93: e13762. https://doi.org/10.1111/asj.13762

・Komatsu T, Komatsu M, Nakajima H, Uemoto Y. (2022) Ultra-rapid real-time PCR assay for genotyping of the NT5E gene in Japanese black beef using a mobile PCR device, PCR 1100. Animal Science Journal, 93: e13763. https://doi.org/10.1111/asj.13763

・Nagai R, Kinukawa M, Watanabe T, Ogino A, Kurogi K, Adachi K, Satoh M, Uemoto Y. (2022) Genomic dissection of repeatability considering additive and non-additive genetic effects for semen production traits in beef and dairy bulls. Journal of Animal Science, 100(9): skac241. https://doi.org/10.1093/jas/skac241

・Kim M, Masaki T, Ikuta K, Iwamoto E, Nishihara K, Hirai M, Uemoto Y, Terada F, Roh S. (2022) Physiological responses and adaptations to high methane production in Japanese Black cattle. Scientific Reports, 12: 11154. https://doi.org/10.1038/s41598-022-15146-1

・Komatsu T, Toita T, Uemoto Y. (2022) Estimates of genetic parameters for adenosine triphosphate-related compounds (ATPRCs) at different aging period and NT5E genotypes in Japanese black beef. Animal Science Journal, 93: e13748. https://doi.org/10.1111/asj.13748

・Hara H, Ogawa S, Ohnishi C, Ishii K, Uemoto Y, Satoh M. (2022) An attempt of using public ambient temperature data in swine genetic evaluation for litter size traits at birth in Japan. Animal Production Science, AN21463. https://doi.org/10.1101/2022.02.09.479814

・Zoda A, Kagawa R, Obinata R, Urakawa M, Oono Y, Ogawa S, Uemoto Y, Satoh M. (2022) Genetic relationship between superovulatory response traits and carcass traits in Japanese Black cattle. Animal Science Journal, 93: e13731. https://doi.org/10.1111/asj.13731

・Wang H, Zhou Y, Xu C, Cao Y, Xiao Y, Cai D, Uemoto Y, Wu S, Bao W. (2022) Genome-wide transcriptional profiling and functional analysis reveal miR-330-MAPK15 axis involving in cellular responses to deoxynivalenol exposure. Chemosphere, 298: 134199. https://doi.org/10.1016/j.chemosphere.2022.134199

・Kim M, Masaki T, Ikuta K, Iwamoto E, Uemoto Y, Terada F, Roh S. (2022) Changes in the liver transcriptome and physiological parameters of Japanese Black steers during the fattening period. Scientific Reports, 12: 4029. https://doi.org/10.21203/rs.3.rs-882318/v1

・Ogawa S, Kimata M, Tomiyama M, Satoh M. (2022) Heritability and genetic correlation estimates of semen production traits with litter traits and pork production traits in purebred Duroc pigs. Journal of Animal Science, 100: skac055. https://doi.org/10.1093/jas/skac055

・Ogawa S, Satoh M. (2022) Genetic contributions of genes on sex chromosomes and mitochondrial DNA in a pedigreed population. Diversity, 14:142. https://doi.org/10.3390/d14020142

・Zoda A, Ogawa S, Matsuda H, Taniguchi Y, Watanabe T, Sugimoto Y, Iwaisaki H. (2022) Inferring genetic characteristics of Japanese Black cattle populations using genome-wide single nucleotide polymorphism markers. The Journal of Animal Genetics, 50(1): 3-9. https://doi.org/10.5924/abgri.50.3

・Nagai R, Kinukawa M, Watanabe T, Ogino A, Kurogi K, Adachi K, Satoh M, Uemoto Y. (2022) Genome-wide detection of non-additive quantitative trait loci for semen production traits in beef and dairy bulls. Animal, 16(3): 100472. https://doi.org/10.1016/j.animal.2022.100472

・Shinoda C, Yasuda J, Yamagata K, Suzuki K, Satoh M, Roh S, Uemoto Y. (2022) Genetic relationships of feed efficiency and growth traits with carcass traits in Japanese Shorthorn cattle. Animal Science Journal, 93: e13691. https://doi.org/10.1111/asj.13691

・Komiya R, Ogawa S, Aonuma T, Satoh M. (2022) Performance of using opposing homozygotes for paternity testing in Japanese Black cattle. Journal of Animal Breeding and Genetics, 139(1): 113-124. https://doi.org/10.1111/jbg.12649

・Takeda M, Inoue I, Oyama H, Uchiyama K, Yoshinari K, Sasago N, Kojima T, Kashima M, Suzuki H, Kamata T, Kumagai M, Takasugi W, Aonuma T, Soma Y, Konno S, Saito T, Ishida M, Muraki E, Inoue Y, Takayama M, Nariai S, Hideshima R, Nakamura R, Nishikawa S, Kobayashi H, Shibata E, Yamamoto K, Yoshimura K, Matsuda H, Inoue T, Fujita A, Terayama S, Inoue K, Morita S, Nakashima R, Suezawa R, Hanamure T, Zoda A, Uemoto Y. (2021) Exploring the size of reference population for expected accuracy of genomic prediction using simulated and real data in Japanese Black cattle. BMC Genomics, 22: 799. https://doi.org/10.1186/s12864-021-08121-z

・Ogawa S, Kitajima S, Saito H, Satoh M. (2021) Deriving economic values for female reproductive traits in lifetime carcass production of Japanese Black cows using deterministic profit function. Agriculture, 11: 1055. https://doi.org/10.3390/agriculture11111055

・Uemoto Y, Suzuki K, Yasuda J, Roh S, Satoh M. (2021) Evaluation of inbreeding and genetic diversity in Japanese Shorthorn cattle by pedigree analysis. Animal Science Journal, 92: e13643. https://doi.org/10.1111/asj.13643

・Homma C, Hirose K, Ito T, Kamikawa M, Toma S, Nikaido S, Satoh M, Uemoto Y. (2021) Estimation of genetic parameter for feed efficiency and resilience traits in three pig breeds. Animal, 15(11): 100384. https://doi.org/10.1016/j.animal.2021.100384

・Zoda A, Urakawa M, Oono Y, Ogawa S, Satoh M. (2021) Estimation of genetic parameters for superovulatory response traits in Japanese Black cows. Journal of Animal Science, 99(10): skab265. https://doi.org/10.1093/jas/skab265

・Uemoto Y, Ichinoseki K, Matsumoto T, Oka N, Takamori H, Kadowaki H, Kojima-Shibata C, Suzuki E, Okamura T, Aso H, Kitazawa H, Satoh M, Uenishi H, Suzuki K. (2021) Genome-wide association studies for production, respiratory disease, and immune-related traits in Landrace pigs. Scientific Reports, 11: 15823. https://doi.org/10.1038/s41598-021-95339-2

・Ogawa S. (2021) Genomic prediction in Japanese Black beef cattle: some topics. Journal of Integrated Field Science, 18: 20-25.

・Ogawa S, Kimata M, Ishii K, Uemoto Y, Satoh M. (2021) Genetic analysis for sow stayability at different parities in purebred Landrace and Large White pigs. Animal Science Journal, 92: e13599. https://doi.org/10.1111/asj.13599

・Ogawa S, Yazaki N, Ohnishi C, Ishii K, Uemoto Y, Satoh M. (2021) Maternal effect on body measurement and meat production traits in purebred Duroc pigs. Journal of Animal Breeding and Genetics, 138(2): 237-245. https://doi.org/10.1111/jbg.12505

・Ogawa S, Satoh M. (2021) Random regression analysis of calving interval of Japanese Black cows. Animals, 11(1): 202. https://doi.org/10.3390/ani11010202

・Ogawa S, Satoh M. (2020) Relationship between litter size at birth and within-litter birth weight characteristics in laboratory mice as pilot animal for pig. Animal Science Journal, 91: e13488. https://doi.org/10.1111/asj.13488

・Ogawa S, Ohnishi C, Ishii K, Uemoto Y, Satoh M. (2020) Genetic relationship between litter size traits at birth and body measurement and production traits in purebred Duroc pigs. Animal Science Journal, 91: e13497. https://doi.org/10.1111/asj.13497

・Takeda M, Uemoto Y, Satoh M. (2020) Effect of the genotyped bulls with different numbers of phenotyped progenies on the quantitative trait loci detection and genomic evaluation in a simulated cattle population. Animal Science Journal, 91: e13432. https://doi.org/10.1111/asj.13432

・Konta A, Ogawa S, Kimata M, Ishii K, Uemoto Y, Satoh M. (2020) Comparison of two models to estimate genetic parameters for number of born alive in pigs. Animal Science Journal, 91: e13417. https://doi.org/10.1111/asj.13417

・Uemoto Y, Takeda M, Ogino A, Kurogi K, Ogawa S, Satoh M, Terada F. (2020) Genetic and genomic analyses for predicted methane-related traits in Japanese Black steers. Animal Science Journal, 91: e13383. https://doi.org/10.1111/asj.13383

・Okamura T, Ishii K, Nishio M, Rosa GJM, Satoh M, Sasaki O. (2020) Inferring phenotypic causal structure among farrowing and weaning traits in pigs. Animal Science Journal, 91: e13369. https://doi.org/10.1111/asj.13369

・Uemoto Y, Ogawa S, Satoh M, Abe H, Terada F. (2020) Development of prediction equation for methane-related traits in beef cattle under high concentrate diets. Animal Science Journal, 91: e13341. https://doi.org/10.1111/asj.13341

・Takeda M, Uemoto Y, Inoue K, Ogino A, Nozaki T, Kurogi K, Yasumori T, Satoh M. (2019) Genome-wide association study and genomic evaluation of feed efficiency traits in Japanese Black cattle using single-step genomic best linear unbiased prediction method. Animal Science Journal, 91: e13316. https://doi.org/10.1111/asj.13316

・Komatsu T, Komatsu M, Uemoto Y. (2019) The NT5E gene variant strongly affects the degradation rate of inosine 5'-monophosphate under postmortem conditions in Japanese Black beef. Meat Science, 158: 107893. https://doi.org/10.1016/j.meatsci.2019.107893

・Ogawa S, Konta A, Kimata M, Ishii K, Uemoto Y, Satoh M. (2019) Genetic relationship of litter traits between farrowing and weaning in Landrace and Large White pigs. Animal Science Journal, 90(12): 1510-1516. https://doi.org/10.1111/asj.13304

・Shimazu T, Borjigin L, Katoh K, Roh S, Kitazawa H, Abe K, Suda Y, Saito H, Kunii H, Nihei K, Uemoto Y, Aso H, Suzuki K. (2019) Addition of Wakame seaweed (Undaria pinnatifida) stalk to animal feed enhances immune response and improves intestinal microflora in pigs. Animal Science Journal, 90(9): 1248-1260. https://doi.org/10.1111/asj.13274

・Ogawa S, Konta A, Kimata M, Ishii K, Uemoto Y, Satoh M. (2019) Genetic parameter estimation for number born alive at different parities in Landrace and Large White pigs. Animal Science Journal, 90(9): 1111-1119. https://doi.org/10.1111/asj.13252

・Darhan H, Zoda A, Kikusato M, Toyomizu M, Katoh K, Roh S, Ogawa S, Uemoto Y, Satoh M, Suzuki K. (2019) Correlations between mitochondrial respiration activity and residual feed intake after divergent genetic selection for high and low oxygen consumption in mice. Animal Science Journal, 90(7): 818-826. https://doi.org/10.1111/asj.13210

・Satoh M. (2019) Evaluation criterion for response to selection with constraint. Animal Science Journal, 90(4): 462-466. https://doi.org/10.1111/asj.13174

・Ogawa S, Konta A, Kimata M, Ishii K, Uemoto Y, Satoh M. (2019) Estimation of genetic parameters for farrowing traits in purebred Landrace and Large White pigs. Animal Science Journal, 90(1): 23-28. https://doi.org/10.1111/asj.13120

・Kawaguchi F, Kigoshi H, Nakajima A, Matsumoto Y, Uemoto Y, Fukushima M, Yoshida E, Iwamoto E, Akiyama T, Kohama N, Kobayashi E, Honda T, Oyama K, Mannen H, Sasazaki S. (2018) Pool-based genome-wide association study identified novel candidate regions on BTA9 and 14 for oleic acid percentage in Japanese Black cattle. Animal Science Journal, 89(8): 1060-1066. https://doi.org/10.1111/asj.13035

・Sasago N, Takeda M, Ohtake T, Abe T, Sakuma H, Kojima T, Sasaki S, Uemoto Y. (2018) Genome-wide association studies identified variants for a concentration of taurine in Japanese Black beef. Animal Science Journal, 89(8): 1051-1059. https://doi.org/10.1111/asj.13030

・Okada D, Endo S, Matsuda H, Ogawa S, Taniguchi Y, Katsuta T, Watanabe T, Iwaisaki H. (2018) An intersection network based on combining SNP co-association and RNA co-expression networks for feed utilization traits in Japanese Black cattle. Journal of Animal Science, 96(7): 2553-2566. https://doi.org/10.1093/jas/sky170

・Ohnishi C, Satoh M. (2018) Estimation of genetic parameters for performance and body measurement traits in Duroc pigs selected for average daily gain, loin muscle area, and backfat thickness. Livestock Science, 214: 161-166. https://doi.org/10.1016/j.livsci.2018.05.022

・Satoh M. (2018) An alternative derivation method of mixed model equations from best linear unbiased prediction (BLUP) and restricted BLUP of breeding values not using maximum likelihood. Animal Science Journal, 89(6): 876-879. https://doi.org/10.1111/asj.13016

・Nakajima A, Kawaguchi F, Uemoto Y, Fukushima M, Yoshida E, Iwamoto E, Akiyama T, Kohama N, Kobayashi E, Honda T, Oyama K, Mannen H, Sasazaki S. (2018) A genome wide association study for fat-related traits computed by image analysis in Japanese Black cattle. Animal Science Journal, 89(5): 743-751. https://doi.org/10.1111/asj.12987

・Takeda M, Uemoto Y, Inoue K, Ogino A, Nozaki T, Kurogi K, Yasumori T, Satoh M. (2018) Evaluation of feed efficiency traits for genetic improvement in Japanese Black cattle. Journal of Animal Science, 96(3): 797-805. http://dx.doi.org/10.3168/jds.2014-9152

・Uemoto Y, Ohtake T, Sasago N, Takeda M, Abe T, Sakuma H, Kojima T, Sasaki S. (2017) Effect of two non-synonymous ecto-5’-nucleotidase variants on the genetic architecture of inosine 5’-monophosphate (IMP) and its degradation products in Japanese Black beef. BMC Genomics, 18: 874. https://doi.org/10.1186/s12864-017-4275-4

・Darhan H, Kikusato M, Toyomizu M, Roh S, Katoh K, Satoh M, Suzuki K. (2017) Selection for high and low oxygen consumption-induced differences in maintenance energy requirements for mice. Animal Science Journal, 88(7): 959-965. https://doi.org/10.1111/asj.12740

・Borjigin L, Shimazu T, Katayama Y, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Satoh M, Suda Y, Sakuma A, Nakajo M, Suzuki K. (2017) Effects of mycoplasmal pneumonia of swine (MPS) lung lesion-selected Landrace pigs on MPS resistance and immune competence in three-way crossbred pigs. Animal Science Journal, 88(4): 575-585. https://doi.org/10.1111/asj.12698

・Borjigin L, Shimazu T, Katayama Y, Li M, Sato T, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M, Suzuki K. (2016) Immunogenic properties of Landrace pigs selected for resistance to mycoplasma pneumonia of swine. Animal Science Journal, 87(3): 321-329. https://doi.org/10.1111/asj.12440

・Borjigin L, Shimazu T, Katayama Y, Li M, Sato T, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M, Suzuki K. (2016) Immunogenic properties and mycoplasmal pneumonia of swine (MPS) lung lesions in Large White pigs selected for higher peripheral blood immune capacity. Animal Science Journal, 87(5): 638-645. https://doi.org/10.1111/asj.12471

・Borjigin L, Shimazu T, Katayama Y, Li M, Sato T, Watanabe K, Kitazawa H, Roh S, Aso H, Katoh K, Uchida T, Suda Y, Sakuma A, Nakajo M, Suzuki K. (2016) Mycoplasma pneumonia of swine (MPS) resistance and immune characteristics of pig lines generated by crossing an MPS pulmonary lesion selected Landrace line and a highly immune capacity selected Large White line. Animal Science Journal, 87(8): 972-981. https://doi.org/10.1111/asj.12529

・Okamura T, Maeda K, Onodera W, Kadowaki H, Kojima-Shibata C, Suzuki E, Uenishi H, Satoh M, Suzuki K. (2016) Correlated responses of respiratory disease and immune capacity traits of Landrace pigs selected for Mycoplasma hyopneumoniae of swine (MPS) lesions. Animal Science Journal, 87(9): 1099-1105. https://doi.org/10.1111/asj.12560

・Hong Y, Ardiyanti A, Kikusato M, Shimazu T, Toyomizu M, Suzuki K. (2015) Selection for high and low oxygen consumption altered hepatic mitochondrial energy efficiency in mice. Animal Science Journal, 86(9): 818-825. https://doi.org/10.1111/asj.12366

・Nishio M, Satoh M. (2015) Genomic best linear unbiased prediction method including imprinting effects for genomic evaluation. Genetics Selection Evolution, 47: 32. https://doi.org/10.1186/s12711-015-0091-y

・Sasaki O, Aihara M, Nishiura A, Takeda H, Satoh M. (2015) Genetic analysis of pseudo-survival rate during lactation of Holstein cattle in Japan using random regression models. Journal of Dairy Science, 98(8): 5781-5795. http://dx.doi.org/10.3168/jds.2014-9152

・Nishio M, Satoh M. (2015) Genomic BLUP method reflecting patterns of linkage disequilibrium. Journal of Animal Breeding and Genetics, 132(5): 357-365. https://doi.org/10.1111/jbg.12162

・Nishiura A, Sasaki O, Aihara M, Takeda H, Satoh M. (2015) Genetic analysis of fat to protein ratio and milk production traits of Holstein cows in Japan in the first three lactations by using a random regression model. Animal Science Journal, 86(12): 961-968. https://doi.org/10.1111/asj.12388

Address新着情報

Laboratory of Animal Breeding and Genetics,
Graduate School of Agricultural Science, Tohoku University
Adress: Aramaki-Aza-Aoba 468-1, Aoba-ku, Sendai, Miyagi 980-8572, Japan

バナースペース

東北大学大学院農学研究科
生物生産科学専攻
動物遺伝育種学分野

〒980-8572
宮城県仙台市青葉区荒巻字青葉468-1 農学系総合研究棟

TEL 022-757-4112(佐藤)
  022-757-4113(上本)