- Alauddin M, Amin MR, Siddique MA, Hiwatashi K, Shimakage A, Takahashi S,
Shinbo M, Komai M, Shirakawa H. In silico and in vivo experiment of soymilk
peptide (tetrapeptide - FFYY) for the treatment of hypertension. Peptides,
in press. [ScienceDirect]
- Hsu F-Y, Suh-Ching Yang S-C, Fat-Moon Suk F-M, Shirakawa H, Chiu W-C, Yi-Jen
Liao Y-J. Dietary rice bran attenuates hepatic stellate cell activation
and liver fibrosis in mice through enhancing antioxidant ability. J. Nutri.
Biochem., in press. [ScienceDirect]
- Wee VTK, Shirakawa H, Yeh S-L, Yeh C-L. Fermented rice bran supplementation
attenuates colonic injury through modulating intestinal aryl hydrocarbon
receptor and innate lymphoid cells in mice with dextran sodium sulfate-induced
acute colitis. J. Nutri. Biochem., 2024, 123, 109493. [ScienceDirect]
- 大崎雄介、白川仁 ビタミンKとビタミンK関連物質による抗炎症作用とその機序 日本栄養・食糧学会誌 (2024) 印刷中
- 岡田和花、大崎雄介、白川仁 認知機能障害モデル動物に対するガラクトース投与の相反する効果 ビタミン (2024) 印刷中
- 塩沢浩太、大崎雄介、白川仁 新規形態のビオチン塩の開発とその効果 ビタミン (2024) 98, 21-24.
- Imoto T, Hoshino Y, Sato Y, Ohsaki Y, Shirakawa H. Eating Habits and Mental
Health of College Students in Japan during the COVID-19 Pandemic. COVID,
2023, 3, 1721–1732. [MDPI]
- Uemoto Y, Katsura T, Endo Y, Tanaka K, Zhuang T, Urakawa M, Baba T, Yoshida
G, Wang H, Kitazawa H, Shirakawa H, Nakamura T, Nochi T, Aso H. Genetic
aspects of immunoglobulins and cyclophilin A in milk as potential indicators
of mastitis resistance in Holstein cows. J. Dairy Sci., in press. [ScienceDirect]
- Kabir T, Yoshiba H, Agista AZ, Sultana H, Ohsaki Y, Chiu-Li Yeh C-L, Hirakawa
R, Tani H, Ikuta T, Nochi T, Yang S-C, Shirakawa H. Protective Effects
of Gnetin C from Melinjo Seed Extract against High Fat Diet-Induced Hepatic
Steatosis and Liver Fibrosis in NAFLD Mice Model. Nutrients, 2023, 15,
3888. [MDPI]
- Huang P-X, Yeh C-L, Yang S-C, Shirakawa H, Chang C-L, Chen L-H, Chiu Y-S,
Chiu W-C. Rice Bran Supplementation Improves Gut Dysbiosis and Mitigate
Muscle Atrophy in Ovariectomized Mice Fed with a High-Fat Diet. Nutrients,
2023, 15, 3514. [MDPI]
- Budijanto S, Nurtiana W, Muniroh A, Kurniati Y, Nuraida L, Priosoeryanto
BP, Dewi FNA, Ardiansyah, Yuliana ND, Safrida S, Shirakawa H. Dietary Supplementation
of Black Rice Bran to Colon Carcinogen-Induced Mice: Examining the Development
of Colorectal Cancer by Improving Environmental Colon Conditions. Heliyon,
2023, 9, e18528. [ScienceDirect]
- Noguchi T, Kitaura H, Marahleh A, Agista AZ, Ohsaki Y, Shirakawa H, Mizoguchi
I. Fermented rice bran supplementation inhibits LPS-induced osteoclast
formation and bone resorption in mice, and fermented rice bran extract
directly inhibits osteoclast formation and TNF-α expression in macrophages.
Nutrients, 2023, 15, 3044. [MDPI]
- Yamaki M, Saito H, Mimori T. Suzuki Y, Nagasaki M, Suzuki K, Satoh-Kuriwada
S, Shoji N, Isono K, Goto T, Shirakawa H, Komai M. Analysis of Genetic
Polymorphism of Bitter Taste Receptor TAS2R38 and TAS2R46, and Its Relationship
with Eating and Drinking Habits in Japanese ToMMo Subjects. J. Nutr. Sci.
Vitaminol., 2023, 69, 347–356. [Jstage]
- Xiao Q, Chen Y-H, Chen Y-L, Chien Y-S, Hsieh L-H, Shirakawa H, Yang S-C.
Potential Benefits of Epidermal Growth Factor for Inhibiting Muscle Degrative
Markers in Rats with Alcoholic Liver Damage. Int. J. Mol. Sci., 2023, 24,
8845. [MDPI]
- Handoko DD, Kaseh AM, Cempaka L, David W, Kusbiantoro B, Agista AZ, Ohsaki
Y, Shirakawa H, Ardiansyah. Effects of household-scale cooking on volatile
compounds, sensory profile, and hypotensive effect of Kenikir (Cosmos caudatus).
AIMS Agri. Food, 2023, 8, 198-213. [AIMS Press]
- Shiozawa K, Maeda M, Ho H-J, Katsurai T, Howlader MZH, Horiuchi K, Sugita
Y, Ohsaki Y, Agista AZ, Goto T, Komai M, Shirakawa H. Biotin enhances testosterone
production in mice and in mouse testis-derived cells. Nutrients, 2022,
14, 4761. [MDPI]
- Nakano T, Hayashi S, Ochiai Y, Shirakawa H, Wu H, Endo H, Yu H. Modification
of the oxygen radical absorbance capacity assay and its application in
evaluating the total antioxidative state in fish. Adv. Redox Res., 2022,
6, 100049. [ScienceDirect]
- Agista AZ, Tanuseputero SA, Koseki T, Ardiansyah, Budijanto S, Sultana
H, Ohsaki Y, Yeh C-L, Yang S-C, Komai M, Shirakawa H. Tryptamine, a microbial
metabolite in fermented rice bran suppressed lipopolysaccharide-induced
inflammation in a murine macrophage model. Int. J. Mol. Sci., 2022, 23,
11209. [MDPI]
- Urakawa M, Zhuang, T, Sato H, Takanashi S, Yoshimura K, Endo Y, Katsura
T, Umino T, Tanaka K, Kobayashi H, Takada N, Kozutsumi T, Kumagai H, Asano
T, Sazawa K, Ashida N, Rose M, Kitazawa H, Shirakawa H, Watanabe K, Nochi
T, Nakamura T, Aso H. Prevention of mastitis in multiparous dairy cows
with a previous history of mastitis by oral feeding with probiotic Bacillus
subtilis. Anim. Sci. J., 2022, 93, e13764. [Wiley]
- Safrida S, Budijanto S, Nuraida L, Priosoeryanto BP, Saepuloh U, Marya
SS, Ardiansyah, Shirakawa H. Fermented Black Rice Bran Extract Inhibit
Colon Cancer Proliferation in WiDr Cell Lines. Food Sci. Technol., 2022,
42, e14422. [SciELO]
- Astuti RD, Fibri DLN, Handoko DD, David W, Budijanto S, Shirakawa H, Ardiansyah.
The volatile compounds and aroma description in various fermented and non-fermented
rice bran. Fermentation, 2022, 8, 120. [MDPI]
- Kuroiwa T, Ohtani Y, Obara Y, Terada F, Watanabe K, Shirakawa H, Komai
M, Satoh H, Sato S, Ichijo T. Effect of vitamin K3 supplementation on Immunoglobulin
G concentration in colostrum of periparturient Holstein dairy cows. Anim.
Sci. J., 2022, 93, e13706. [Wiley]
- Chen T-Y, Chen Y-L, Chiu W-C, Yeh C-L, Tung Y-T, Shirakawa H, Liao W-T,
Yang S-C. Effects of the water extract of fermented rice bran on liver
damage and intestinal injury in aged rats with high-fat diet feeding. Plants,
2022, 11, 607. [MDPI]
- Nadhifah AM, Fibri DLN, Handoko DD, David W, Budijanto S, Shirakawa H,
Ardiansyah. The volatile compounds and aroma profile of pigmented rice
bran after fermentation. Curr. Res. Nutr. Food Sci., 2022, 10, 145-170.
[CRNFSJ]
- Bai H, Arai H, Ikuta K, Ishikawa S, Ohtani Y, Iwashita K, Okada N, Shirakawa
H, Komai M, Terada F, Obara Y. Effects of dietary vitamin K3 supplementation
on vitamin K1 and K2 (menaquinone) dynamics in dairy cows. Anim. Sci. J.,
2022, 93, e13680. [Wiley]
- Ho H-J, Shirakawa H. Oxidative Stress and Mitochondrial Dysfunction in
Chronic Kidney Disease. Cells 2022, 12, 88. [MDPI]
- Mizuno K, Watanabe K, Yamano E, Ebisu K, Tajima K, Nojima J, Ohsaki Y,
Kabayama S, Watanabe Y. Antioxidant effects of continuous intake of electrolyzed
hydrogen water in healthy adults. Heliyon, 2022, 8, e11853. [ScienceDirect]
- Matsuki T, Hirose T, Ohsaki Y, Shimada S, Endo A, Ito H, Takahashi C, Yamakoshi
S, Oba-Yabana I, Anan G, Kato T, Tajima R, Nakayama S, Kimura T, Nakamura
H, Tani J, Takahashi K, Kure S, Mori T. Inhibition of platelet-derived
growth factor pathway suppresses tubulointerstitial injury in renal congestion.
J. Hypertens., 2022, 40, 1935-1949. [Lippincott]
- Islam J, Agista AZ, Watanabe K, Nochi T, Aso H, Ohsaki Y, Koseki T, Komai
M, Shirakawa H. Fermented rice bran supplementation attenuates chronic
colitis-associated extraintestinal manifestations in female C57BL/6N mice.
J. Nutr. Biochem., 2022, 99, 108855. [ScienceDirect]
- Ogawa S, Ohsaki Y, Shimizu M, Nako K, Okamura M, Kabayama S, Tabata K,
Tanaka Y, Ito S. Electrolyzed hydrogen-rich water for oxidative stress
suppression and improvement of insulin resistance: a multicenter prospective
double-blind randomized control trial. Diabetol. Int., 2022, 13, 209-219.
[SpringerLink]
- Shiozawa K, Agista AZ, Ohsaki Y, Shirakawa H. Emergence of Novel Functions
of Vitamins for the Prevention of Life-Style Related Diseases. J. Nutr.
Sci. Vitaminol., 2022, 68, S8-S10. [Jstage]
- 大崎雄介、Afifah Zahra Agista、白川仁 ピリドキサミンによる神経保護を介した統合性失調症改善の可能性 ビタミン (2022)
96, 474-476. [日本ビタミン学会]
- 大崎雄介、塩沢浩太、白川仁 糖尿病と高血圧に対して期待されるビオチンの効果 食と医療 （2022）22, 65-70.
- Chen Y-H, Chiu W-C, Xiao Q, Chen Y-L, Shirakawa H, Yang S-C. Synbiotics
alleviate hepatic dame, intestinal injury and muscular beclin-1 elevation
in rats after chronic ethanol administration. Int. J. Mol. Sci., 2021,
22, 12547. [MDPI]
- Saputra WD, Shono H, Ohsaki Y, Sultana H, Komai M, Shirakawa H. Geranylgeraniol
Inhibits Inflammation induced by Lipopolysaccharide in MG6 mouse microglial-derived
cells via NF-κB signaling modulation. Int. J. Mol. Sci., 2021, 11, 10543.
[MDPI]
- Sultana H, Komai M, Shirakawa H. Role of Vitamin K in Cholestatic Liver
Disease. Nutrients 2021, 13, 2515. [MDPI]
- Xiao Q, Chen Y-H, Pratama SA, Y Chen Y-L, Shirakawa H, Peng H-C, Yang S-C.
The Prophylactic Effects of Glutamine on Muscle Protein Synthesis and Degradation
in Rats with Ethanol-Induced Liver Damage. Nutrients, 2021, 13, 2788. [MDPI]
- Agista AZ, Rusbana TB, Islam J, Ohsaki Y, Sultana H, Hirakawa R, Watanabe
K, Nochi T, Ardiansyah, Slamet Budijanto S, Yang SC, Koseki T, Aso H, Komai
M, Shirakawa H. Fermented rice bran supplementation prevented the development
of intestinal fibrosis due to DSS-induced inflammation in mice. Nutrients,
2021, 13, 1869. [MDPI]
- Ardiansyah, Nada A, Rahmawati NTI, Oktriani A, David W, Astuti RM, Handoko
DD, Kusbiantoro B, Budijanto S, Shirakawa H. Volatile Compounds and Sensory
Profile of Fermented Rice Bran. Plants, 2021, 10, 1073. [MDPI]
- Sultana H, Kato A, Ohashi A, Takashima R, Katsurai T, Sato S, Monma M,
Ohsaki Y, Goto T, Komai M, Shirakawa H. Effect of vitamin K-mediated PXR
activation on drug-metabolizing gene expression in human intestinal carcinoma
LS180 cell line. Nutrients, 2021, 13, 1709. [MDPI]
- Rana MM, Shiozawa K, Mukai K, Takayanagi K, Eguchi K, Sultana H, Ohsaki
Y, Komai M, Shirakawa H. S-allyl Cysteine Enhances Testosterone Production
in Mice, and Mouse Testis Derived I-10 Cells. Molecules, 2021, 26, 1697.
[MDPI]
- Sotome R, Hirasawa A, Kikusato M, Kuriyagawa A, Watanabe K, Furukawa K,
Collin A, Amo T, Shirakawa H, Takahashi H, Wu G, Nochi T, Shimmura T, Walden
CH, Toyomizu M. In vivo emergence of beige-like fat in chickens as physiological
adaptation to cold environments. Amino Acid, 2021, 53, 381-393. [PMC]
- Ardiansyah, Ariffa F, Astuti RM, David W, Handoko DD, Budijanto S, Shirakawa
H. Non-volatile compounds and blood pressure lowering activity of Inpari
30 and Cempo Ireng fermented and non-fermented rice bran. AIMS Agri. Food,
2021, 6, 337-359. [AIMS Press]
- Hsu C-D, Hsieh L-H, Chen Y-L, Lin I-C, Chen Y-R, Chen C-C, Shirakawa H,
Yang S-C. Complementary effects of pine bark extract supplementation on
inattention, impulsivity and antioxidative status in children with attention-deficit
hyperactivity disorder: a double-blinded randomized placebo-controlled
crossover study. Phytother. Res., 2021, 35, 3226-3235. [Pubmed]
- Yamakoshi S, Ito O, Rong R, Ohsaki Y, Nakamura T, Hirose T, Takahashi K,
Mori T, Totsune K, Kohzuki M. High Salt Intake-Increased (Pro)renin Receptor
Expression Is Exaggerated in the Kidney of Dahl Salt-Sensitive Rats Hypertension,
2021, 75, 1447-1454. [Pubmed, AHA/ASA]
- Nakayama Y, Ho H-J, Yamagishi M, Ikemoto H, Komai M, Shirakawa H. Cysteine
sulfoxides enhance steroid hormone production via activation of the protein
kinase A pathway in testis-derived I-10 tumor cells. Molecules, 2020, 25,
4694. [MDPI]
- Chen Y-L, Shirakawa H, Lu N-S, Peng H-C, Xiao Q, Yang S-C. Impacts of Fish
Oil on the Gut Microbiota of Rats with Alcoholic Liver Damage. J. Nutr.
Biochem., 2020, 86, 108491. [Pubmed, ScienceDirect]
- Tsunoda Y, Hano S, Imoto N, Shibuya T, Ikeda H, Amagaya K, Kato K, Shirakawa
H, Aso H, Omura M, Kanayama. Physiological roles of tryptophan decarboxylase
revealed by overexpression of SlTDC1 in tomato. Sci. Hortic., 2021, 275,
109672. [ScienceDirect]
- Ho H-J, Komai M, Shirakawa H. Beneficial Effects of Vitamin K Status on
Glycemic Regulation and Diabetes Mellitus: A Mini-Review. Nutrients, 2020,
12, 2485. [MDPI]
- Rusbana TB, Agista AZ, Saputra WD, Ohsaki Y, Watanabe, Ardiansyah, Budijanto
S, Koseki T, Aso H, Komai M, Shirakawa H. Supplementation with Fermented
Rice Bran Attenuates Muscle Atrophy in a Diabetic Rat Model. Nutrients,
2020, 12, 2409. [MDPI]
- Yamada K, Sakuma W, Agista AZ, Nakamura K, Ohsaki Y, Sakurai H, Komai M,
Shirakawa H. Liver hydrolysate reduces LPS-induced inflammation by regulating
the NF-κβ pathway in RAW 264.7 macrophages. Jpn. Pharmacol. Ther., 2020,
48, 1139-1144.
- Matsuno Y, Atsumi Y, Alauddin Md, Rana MM, Fujimori H, Hyodo M, Shimizu
A, Ikuta T, Tani H, Torigoe H, Nakatsu Y, Tsuzuki T, Komai M, Shirakawa
H, Yoshioka K. Resveratrol and its Related Polyphenols Contribute to the
Maintenance of Genome Stability. Sci. Rep., 2020, 10, 5388. [Pubmed, springernature]
- Yamada K, Ueda K, Shirakawa H, Giriwono PE, Honda S, Sakurai H, Komai M.
The effect of liver hydrolysate on chronic ethanol-induced hepatic injury
in normal rats. Biol. Pharm. Bull., 2020, 43, 554-557. [Pubmed, Jstage]
- Lu N-S, Chiu W-C, Chen Y-L, Peng H-C, Shirakawa H, Yang S-C. Fish oil up-regulates
hepatic autophagy in rats with chronic ethanol consumption. J. Nutr. Biochem.,
2020, 77, 108314. [Pubmed]
- Yang S-C, Huang W-C, Ng X-E, Lee M-C, Hsu Y-J, Huang C-C, Wu H-H, Yeh C-L,
Shirakawa H, Budijanto S, Tung Y-T. Rice BranPrevents Obesity and Modulates
Lipid Metabolism in Rats with High-Energy-Diet-Induced Obesity. Nutrients,
2019, 11, 2033. [MDPI]
- Kabir Y, Shirakawa H, Komai M. Nutritional composition of indigenous cultivar
of black cumin seeds from Bangladesh. Prog. Nutr., 2019, 21, 428-434. [Prognutr]
- Giriwono PE, Shirakawa H, Ohsaki Y, Sato S, Aoyama Y, Ho H-J, Goto T, Komai
M. Geranylgeraniol Suppresses the expression of IRAK1 and TRAF6 to Inhibit
NFκB Activation in Lipopolysaccharide -induced Inflammatory Responses in
Human Macrophage-like Cell. Int. J. Mol. Sci., 2019, 20, 2320. [MDPI]
- Saputra WD, Aoyama N, Komai M, Shirakawa H. Menaquinone-4 Suppresses Lipopolysaccharide-Induced
Inflammation in MG6 Mouse Microglial-Derived Cells by Inhibiting the NF-κB
Signaling Pathway. Int. J. Mol. Sci., 2019, 20, 2317. [MDPI]
- Ho H-J, Shirakawa H, Hirahara K, Sone H, Kamiyama S, Komai M. Menaquinone-4
amplified glucose-stimulated insulin secretion in isolated mouse pancreatic
islets and INS-1 rat insulinoma cells. Int. J. Mol. Sci., 2019, 20, 1995.
[MDPI]
- Katayama M, Kiyono T, Kuroda K, Ueda K, Onuma M, Shirakawa H, Fukuda T.
Rat-derived feeder cells immortalized by expression of mutant CDK4, cyclin
D, and telomerase can support stem cell growth. Biochim. Biophys. Acta
Mol. Cell Res., 2019, 866, 945-956. [Pubmed]
- Ardiansyah, David W, Handoko D, Kusbiantoro B, Budijanto S, Shirakawa H.
Fermented rice bran extract improves blood pressure and glucose in stroke-prone
spontaneously hypertensive rats. Nutr. Food Sci., 2019, 49, 844-853. [Researchgate]
- Alauddin M, Rahmna S, Islam J, Shirakawa H, Komai M, Howlader MZH. Development
of Rice Bran Functional Food and Evaluation of Its Healthful Properties.
DOI: 10.1016/B978-0-12-812828-2.00008-110.5772/66298. "Rice Bran and
Rice Bran Oil. Chemistry, Processing and Utilization", edited by Ling-Zhi
Cheong, Xuebing Xu, ISBN 978-0-12-812828-2, Published: 2019, Academic Press,
London, UK